Hostname: page-component-cd9895bd7-jkksz Total loading time: 0 Render date: 2024-12-26T08:08:59.087Z Has data issue: false hasContentIssue false

Casein hydrolyzate for drying-off lactating mammary quarters in cows with chronic mastitis

Published online by Cambridge University Press:  17 May 2021

Melina M. Barcelos
Affiliation:
Department of Animal Nutrition and Production, School of Veterinary Medicine and Animal Science, University of São Paulo, Pirassununga 13635-900, São Paulo, Brazil
Gustavo Freu
Affiliation:
Department of Animal Nutrition and Production, School of Veterinary Medicine and Animal Science, University of São Paulo, Pirassununga 13635-900, São Paulo, Brazil
Bruna G. Alves
Affiliation:
Department of Animal Nutrition and Production, School of Veterinary Medicine and Animal Science, University of São Paulo, Pirassununga 13635-900, São Paulo, Brazil
Camylla P. Monteiro
Affiliation:
Department of Animal Nutrition and Production, School of Veterinary Medicine and Animal Science, University of São Paulo, Pirassununga 13635-900, São Paulo, Brazil
Marcos V. Santos*
Affiliation:
Department of Animal Nutrition and Production, School of Veterinary Medicine and Animal Science, University of São Paulo, Pirassununga 13635-900, São Paulo, Brazil
*
Author for correspondence: Marcos V. dos Santos, Email: [email protected]

Abstract

In this research communication we address the hypothesis that a single intramammary infusion of casein hydrolyzate (CH) would have a similar effect to three intramammary infusions of CH for drying-off quarters with chronic mastitis (CM) during lactation. Sixty cows with CM were selected and randomly distributed into two treatment groups: (a) three intramammary CH infusions (100 mg, 50 ml per infusion, with 24-h intervals) or (b) single intramammary CH infusion (300 mg, 50 ml). Milk samples from the treated and untreated quarters were collected for microbiological culture and somatic cell count (SCC) before and after CH infusions. Milk yield was recorded and a manual pressure index measurement was used to evaluate cessation of lactation. Of the 60 quarters selected, 43 (71.67%) had positive microbiological culture. The quarters treated with three intramammary CH infusions had higher udder pressure index than those treated with single CH infusion. However, the average milk yield and composite SCC of three functional quarters were not different among treatments. Therefore, a single infusion of CH has the potential to be used as an alternative method for drying-off mammary quarters with CM during lactation.

Type
Research Article
Copyright
Copyright © The Author(s), 2021. Published by Cambridge University Press on behalf of Hannah Dairy Research Foundation

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Barcelos, MM, Martins, L, Grenfell, RC, Juliano, L, Anderson, KL, dos Santos, MV and Gonçalves, JL (2019) Comparison of standard and on-plate extraction protocols for identification of mastitis-causing bacteria by MALDI-TOF MS. Brazilian Journal of Microbiology 50, 849857.CrossRefGoogle ScholarPubMed
Cardozo, LL, Thaler Neto, A, Souza, GN, Picinin, LC, Felipus, NC, Reche, NL, Schmidt, FA, Werncke, D and Simon, EE (2015) Risk factors for the occurrence of new and chronic cases of subclinical mastitis in dairy herds in southern Brazil. Journal of Dairy Science 98, 76757685.CrossRefGoogle ScholarPubMed
Leitner, G, Jacoby, S, Maltz, E and Silanikove, N (2007) Casein hydrolyzate intramammary treatment improves the comfort behavior of cows induced into dry-off. Livestock Science 110, 292297.CrossRefGoogle Scholar
Leitner, G, Koren, O, Jacoby, S, Merin, U and Silanikove, N (2012) Options for handling chronic subclinical mastitis during lactation in modern dairy farms. Israel Journal of Veterinary Medicine 67, 162169.Google Scholar
Schukken, YH, Wilson, DJ, Welcome, F, Garrison-Tikofsky, L and Gonzalez, RN (2003) Monitoring udder health and milk quality using somatic cell counts. Veterinary Research 34, 579596.CrossRefGoogle ScholarPubMed
Shamay, A, Shapiro, F, Mabjeesh, SJ and Silanikove, N (2002) Casein-derived phosphopeptides disrupt tight junction integrity, and precipitously dry up milk secretion in goats. Life Sciences 70, 27072719.CrossRefGoogle ScholarPubMed
Shamay, A, Shapiro, F, Leitner, G and Silanikove, N (2003) Infusions of casein hydrolyzates into the mammary gland disrupt tight junction integrity and induce involution in cows. Journal of Dairy Science 86, 12501258.CrossRefGoogle ScholarPubMed
Silanikove, N, Iscovich, J and Leitner, G (2005) Therapeutic treatment with casein hydrolysate eradicate effectively bacterial infection in treated mammary quarters in cows. In Hogeveen, H (ed.), Mastitis in Dairy Production: Current Knowledge and Future Solutions. Wageningen, the Netherlands: Wageningen Academic Publishers, pp. 327332.Google Scholar
Skarbye, AP, Krogh, MA and Sørensen, JT (2018) The effect of individual quarter dry-off in management of subclinical mastitis on udder condition and milk production in organic dairy herds: a randomized field trial. Journal of Dairy Science 101, 1118611198.CrossRefGoogle ScholarPubMed
tho Seeth, M, Wente, N, Paduch, J-H, Klocke, D, Hoedemaker, M and Krömker, V (2016) Drying-off single udder quarters of dairy cattle during lactation using a casein hydrolysate. Milchwissenschaft 69, 2326.Google Scholar
Supplementary material: PDF

Barcelos et al. supplementary material

Barcelos et al. supplementary material

Download Barcelos et al. supplementary material(PDF)
PDF 264.2 KB