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A Study of Heterozygote Arrays in Relation to the Age Distribution of An Australian Population Sample

Published online by Cambridge University Press:  31 July 2008

C. J. Brackenridge
Affiliation:
Department of Psychiatry, University of Melbourne, Victoria, Australia

Summary

To explore the relation between arrays of multiple genetic systems and the age structure of a population, twelve plasma and red blood-cell polymorphisms were considered in combination. A comparison of observed and expected numbers of persons sharing an array indicated that 72·1% of arrays were in excess of expectation, largely due to association between over-representation and simple heterozygosity score. There was evidence of association between heterozygote excess and age, the proportion of over-represented arrays falling with increase in age. Some implications of this result are discussed.

Type
Research Article
Copyright
Copyright © 1981, Cambridge University Press

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