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Do dietary patterns and morbidities have a relationship with primary infertility among women? A study from NFHS-4 (2015–16), India

Published online by Cambridge University Press:  18 June 2021

Sayeed Unisa ,
Kanchan Negi Open the ORCID record for Kanchan Negi [Opens in a new window] ,
Sucharita Pujari  and
Vaishali Chaurasia Open the ORCID record for Vaishali Chaurasia [Opens in a new window]
Sayeed Unisa
Affiliation:
International Institute for Population Sciences (IIPS), Mumbai, India
Kanchan Negi
Affiliation:
International Institute for Population Sciences (IIPS), Mumbai, India
Sucharita Pujari
Affiliation:
National Institute of Rural Development & Panchayati Raj (NIRDPR), Hyderabad, India
Vaishali Chaurasia*
Affiliation:
International Institute for Population Sciences (IIPS), Mumbai, India
*
*Corresponding author. Email: [email protected]
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Abstract

This study assessed the rate of primary infertility and its associated factors among 402,807 currently married women aged 20–49 years in India using National Family Health Survey-4 data collected in 2015–2016. Dietary patterns and selected morbidities were included as independent variables, and socioeconomic variables were considered as covariates. Bivariate and multivariate analyses were done to estimate the prevalence of primary infertility and assess its association with the selected variables, respectively. The rate of primary infertility among currently married women in India in 2015–16 was 1.9% and this was significantly associated with younger age (<35 years), higher age at marriage (≥18 years), urban residence, higher secondary or above education and poverty. The consumption of dairy products (OR = 0.79, CI = 0.73–0.86), dark green leafy vegetables (OR = 0.57, CI = 0.39–0.81) and fruit (OR = 0.88, CI = 0.77–1.01) significantly reduced the odds of primary infertility. Daily consumption of fish and aerated drinks was related to 1.06–1.21 times higher odds of primary infertility. Overweight/obesity, high blood pressure and high blood glucose levels were associated with 1.08–1.21 times elevated odds of primary infertility. Thyroid disorder (OR = 1.38, CI = 1.21–1.60), heart disease (OR = 1.17, CI = 1.16–1.19) and severe anaemia (OR = 1.24, CI = 1.00–1.53) were associated with an increased likelihood of primary infertility among women (OR 1.17–1.39, CI 1.00–1.60). The findings provide compelling evidence that primary infertility among women is related to dietary patterns and morbidities. Interventions and programmes targeting the promotion of healthy diets and lifestyles could be beneficial in addressing the issue of primary infertility among women.

Keywords

Primary infertilityDietary patternsMorbidities
Type
Research Article
Information
Journal of Biosocial Science , Volume 54 , Issue 4 , July 2022 , pp. 682 - 697
Copyright
© The Author(s), 2021. Published by Cambridge University Press

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References

Agbaje, IM, Rogers, DA, McVicar, CM, McClure, N, Atkinson, AB et al. (2007) Insulin dependent diabetes mellitus: implications for male reproductive function. Human Reproduction 22(7), 1871–1877.10.1093/humrep/dem077CrossRefGoogle ScholarPubMed
Agrawal, P, Agrawal, S and Unisa, S (2012) Spatial, socio-economic and demographic variation of childlessness in India: a special reference to reproductive health and marital breakdown. Global Journal of Medicine and Public Health 1(6), 1–15.Google Scholar
Al Awlaqi, A, Alkhayat, K and Hammadeh, ME (2016) Metabolic syndrome and infertility in women. International Journal of Women’s Health and Reproduction Sciences 4(3), 89–95.CrossRefGoogle Scholar
Amadu, A, Kabir, N, Bolori, MT, Ahmad, IM and Yunusa, I (2018) Soft drinks associate with low levels of some bone and infertility markers in women. Sumerianz Journal of Biotechnology 1(1), 25–29.Google Scholar
Amaral, S, Oliveira, PJ and Ramalho-Santos, J (2008) Diabetes and the impairment of reproductive function: possible role of mitochondria and reactive oxygen species. Current Diabetes Reviews 4(1), 46–54.Google ScholarPubMed
Astrup, A, Dyerberg, J, Selleck, M and Stender, S (2008) Nutrition transition and its relationship to the development of obesity and related chronic diseases. Obesity Reviews 9, 48–52.10.1111/j.1467-789X.2007.00438.xCrossRefGoogle Scholar
Baranwal, A and Chattopadhyay, A (2020) Proposition of belief and practice theory for men undergoing infertility treatment: a hospital based study in Mumbai, India. Frontiers in Sociology 5, 43.CrossRefGoogle ScholarPubMed
Bauer, K, Larson, N, Nelson, M, Story, M and Neumark-Sztainer, D (2009) Fast food intake among adolescents: secular and longitudinal trends from 1999 to 2004. Preventive Medicine 48, 284–287.CrossRefGoogle ScholarPubMed
Bener, A, Al-Ansari, AA, Zirie, M and Al-Hamaq, AOAA (2009) Is male fertility associated with type 2 diabetes mellitus? International Urology and Nephrology 41(4), 777–784.CrossRefGoogle ScholarPubMed
Biradar, SM, Poornima, RT, Sonagra, AD and Jayaprakash Murthy, DS (2012) Thyroid dysfunction in infertile women. International Journal of Pharma and BioSciences 2(3), 53–58.Google Scholar
Boivin, J, Bunting, L, Collins, JA and Nygren, KG (2007) International estimates of infertility prevalence and treatment seeking: potential need and demand for infertility medical care. Human Reproduction 22(6), 1506–1512.CrossRefGoogle ScholarPubMed
Buck, GM, Vena, JE, Schisterman, EF, Dmochowski, J, Mendola, P et al. (2000) Parental consumption of contaminated sport fish from Lake Ontario and predicted fecundability. Epidemiology 11(2) 388–393.CrossRefGoogle ScholarPubMed
Catherin, N, Rock, B, Roger, V, Ankita, C, Ashish, G, Delwin, P, Deeepthi, S and Goud, BR (2015) Beliefs and practices regarding nutrition during pregnancy and lactation in a rural area in Karnataka, India: a qualitative study. International Journal of Community Medicine and Public Health 2(2), 116–120.CrossRefGoogle Scholar
Cekici, H (2018) Current nutritional factors affecting fertility and infertility. Annals of Clinical and Laboratory Research 6(1), 1–5.CrossRefGoogle Scholar
Chakona, G and Shackleton, C (2019) Food taboos and cultural beliefs influence food choice and dietary preferences among pregnant women in the Eastern Cape, South Africa. Nutrients 11(11), 2668.CrossRefGoogle ScholarPubMed
Chavarro, JE, Rich-Edwards, JW, Rosner, BA and Willett, WC (2007) Diet and lifestyle in the prevention of ovulatory disorder infertility. Obstetrics and Gynecology 110 (5), 1050–1058..CrossRefGoogle ScholarPubMed
Chavarro, JE, Rich-Edwards, JW, Rosner, BA and Willett, WC (2008) Protein intake and ovulatory infertility. American Journal of Obstetrics and Gynecology 198(2), 210.e1–210.e2107.CrossRefGoogle ScholarPubMed
Chevrier, C, Warembourg, C, Gaudreau, E, Monfort, C, Le Blanc, A et al. (2013) Organochlorine pesticides, polychlorinated biphenyls, seafood consumption, and time-to-pregnancy. Epidemiology 24(1), 251–260.CrossRefGoogle ScholarPubMed
Choy, CM, Lam, CW, Cheung, LT, Briton-Jones, CM, Cheung, LP et al. (2002) Infertility, blood mercury concentrations and dietary seafood consumption: a case-control study. BJOG: An International Journal of Obstetrics and Gynaecology 109(10), 1121–1125.Google ScholarPubMed
Crosignani, PG, Colombo, M, Vegetti, W, Somigliana, E, Gessati, A et al. (2003) Overweight and obese anovulatory patients with polycystic ovaries: parallel improvements in anthropometric indices, ovarian physiology and fertility rate induced by diet. Human Reproduction 18(9), 1928–1932.CrossRefGoogle Scholar
Cui, W (2010) Mother or nothing: the agony of infertility. Bulletin of the World Health Organization 88(12), 881.CrossRefGoogle ScholarPubMed
Dag, ZÖ and Dilbaz, B (2015) Impact of obesity on infertility in women. Journal of the Turkish German Gynecology Association 16(2), 111–117.Google ScholarPubMed
Delormier, T, Frohlich, KL, Potvin, L (2009) Food and eating as social practice–understanding eating patterns as social phenomena and implications for public health. Sociology of Health & Illness 31(2), 215–228.CrossRefGoogle ScholarPubMed
Eisenberg, ML, Kim, S, Chen, Z, Sundaram, R, Schisterman, EF et al. (2014) The relationship between male BMI and waist circumference on semen quality: data from the LIFE study. Human Reproduction 29(2), 193–200.CrossRefGoogle ScholarPubMed
Capri Workshop Group, ESHRE (2006) Nutrition and reproduction in women. Human Reproduction Update 12(3), 193–207.CrossRefGoogle Scholar
Farhud, DD (2015) Impact of lifestyle on health. Iranian Journal of Public Health 44(11), 1442–1444.Google ScholarPubMed
Farland, LV, Grodstein, F, Srouji, SS, Forman, JP, Rich-Edwards, J et al. (2015) Infertility, fertility treatment, and risk of hypertension. Fertility and Sterility 104(2), 391–397.CrossRefGoogle ScholarPubMed
Fernandez, R, Rolley, JX, Rajaratnam, R, Everett, B and Davidson, PM (2015) Reducing the risk of heart disease among Indian Australians: knowledge, attitudes, and beliefs regarding food practices – a focus group study. Food and Nutrition Research 59(1), 25770.CrossRefGoogle ScholarPubMed
Gade, EJ, Thomsen, SF, Lindenberg, S and Backer, V (2014) Female asthma has a negative effect on fertility: What is the connection? International Scholarly Research Notices 1–6, doi.org/10.1155/2014/131092.Google Scholar
Gade, EJ, Thomsen, SF, Lindenberg, S and Backer, V (2016) Fertility outcomes in asthma: a clinical study of 245 women with unexplained infertility. European Respiratory Journal 47(4), 1144–1151.CrossRefGoogle ScholarPubMed
Gambineri, A, Patton, L, Altieri, P, Pagotto, U, Pizzi, C, et al. (2012) Polycystic ovary syndrome is a risk factor for type 2 diabetes: results from a long-term prospective study. Diabetes 61(9), 2369–2374.CrossRefGoogle ScholarPubMed
Ganguly, S and Unisa, S (2010) Trends of infertility and childlessness in India: findings from NFHS data. Facts, Views and Vision in ObGyn 2(2), 131–138.Google ScholarPubMed
Gaskins, AJ and Chavarro, JE (2018) Diet and fertility: a review. American Journal of Obstetrics and Gynecology 218(4), 379–389.CrossRefGoogle ScholarPubMed
Greenlee, AR, Arbuckle, TE and Chyou, PH (2003) Risk factors for female infertility in an agricultural region. Epidemiology 14(4), 429–443.CrossRefGoogle Scholar
Grieger, JA, Grzeskowiak, LE, Bianco-Miotto, T, Jankovic-Karasoulos, T, Moran, LJ et al. (2018) Pre-pregnancy fast food and fruit intake is associated with time to pregnancy. Human Reproduction 33(6), 1063–1070.CrossRefGoogle ScholarPubMed
Grzeskowiak, LE, Smithers, LG, Grieger, JA, Bianco-Miotto, T, Leemaqz, SY et al. (2018) Asthma treatment impacts time to pregnancy: evidence from the international SCOPE study. European Respiratory Journal 51(2), doi.org/10.1183/13993003.02035-2017.CrossRefGoogle Scholar
Gupta, A and Mishra, DK (2014) Food consumption pattern in rural India: a regional perspective. Journal of Economic and Social Development 9(1), 1–6.Google Scholar
Hanson, B, Johnstone, E, Dorais, J, Silver, B, Peterson, CM et al. (2017) Female infertility, infertility-associated diagnoses, and comorbidities: a review. Journal of Assisted Reproduction and Genetics 34(2), 167–177.CrossRefGoogle ScholarPubMed
Hatch, EE, Wesselink, AK, Hahn, KA, Michiel, JJ, Mikkelsen, EM et al. (2018) Intake of sugar-sweetened beverages and fecundability in a North American preconception cohort. Epidemiology 29(3), 369–378.CrossRefGoogle Scholar
Hatch, EE, Wise, LA, Mikkelsen, EM, Christensen, T, Riis, AH et al. (2012) Caffeinated beverage and soda consumption and time to pregnancy. Epidemiology 23(3), 393.CrossRefGoogle ScholarPubMed
Hussein, MO, Abdelgadir, MA and Mohammed, MN (2019) Anemia and women subfertility. Saudi Journal of Biomedical Research, doi.org/10.36348/sjbr.2019.v04i12.003.Google Scholar
Imai, A, Ichigo, S, Takagi, H, Matsunami, K, Suzuki, N et al. (2010) Effects of cola intake on fertility: a review. Health 2(9), 997–1001.CrossRefGoogle Scholar
IIPS (2009) District Level Household and Facility Survey (DLHS-3), 2007–08. IIPS, India.Google Scholar
IIPS and ICF (2017) National Family Health Survey (NFHS-4) 2015–16 India. International Institute for Population Sciences (IIPS) and ICF. URL: https://doi.org/kwm120 [pii]10.1093/aje/kwm120.Google Scholar
Jonasson, JM, Brismar, K, Sparén, P, Lambe, M, Nyrén, O et al. (2007) Fertility in women with type 1 diabetes: a population-based cohort study in Sweden. Diabetes Care 30(9), 2271–2276.CrossRefGoogle ScholarPubMed
Katole, A and Saoji, AV (2019) Prevalence of primary infertility and its associated risk factors in urban population of central India: a community-based cross-sectional study. Indian Journal of Community Medicine 44(4), 337.CrossRefGoogle ScholarPubMed
Lalani, S, Nizami, I, Hashmi, AA, Saifuddin, A and Rehman, R (2017) Thyroid dysfunction and infertility treatment. Acta Endocrinologica 13(3), 302–307.CrossRefGoogle ScholarPubMed
Li, YQ, Cao, XX, Bai, B, Zhang, JN, Wang, MQ et al. (2014) Severe iron deficiency is associated with a reduced conception rate in female rats. Gynecologic and Obstetric Investigation 77(1), 19–23.CrossRefGoogle ScholarPubMed
Livshits, A and Seidman, DS (2009) Fertility issues in women with diabetes. Women’s Health 5(6), 701–707.Google ScholarPubMed
Lorzadeh, N, Kazemirad, N and Kazemirad, Y (2020) Human immunodeficiency: extragonadal comorbidities of infertility in women. Immunity Inflammation and Disease 8(3), 447–457.CrossRefGoogle ScholarPubMed
Madjdian, DS and Bras, HA (2016) Family, gender, and women’s nutritional status: a comparison between two Himalayan communities in Nepal. Economic History of Developing Regions 31(1), 198–223.CrossRefGoogle Scholar
Mandoura, N, Al-Raddadi, R, Abdulrashid, O, Shah, HB, Kassar, SM et al (2017) Factors associated with consuming junk food among Saudi adults in Jeddah City. Cureus 9(12), e2008.Google ScholarPubMed
Mascarenhas, MN, Flaxman, SR, Boerma, T, Vanderpoel, S and Stevens, GA (2012) National, regional, and global trends in infertility prevalence since 1990: a systematic analysis of 277 health surveys. PLoS Medicine 9(12), e1001356.CrossRefGoogle ScholarPubMed
Moridi, A, Roozbeh, N, Yaghoobi, H, Soltani, S, Dashti, S et al. (2019) Etiology and risk factors associated with infertility. International Journal of Womens Health and Reproduction Sciences 7(3), 346–353.CrossRefGoogle Scholar
Nalavade, D, Shekar, A and Shah, K (2016) Eating patterns and nutrient intakes of women who have problems with fertility. International Journal of Pure and Applied Bioscience 4(4), 198–204.CrossRefGoogle Scholar
Olooto, WE, Amballi, AA and Banjo, TA (2012) A review of female infertility; important etiological factors and management. Journal of Microbiology and Biotechnology Research 2(3), 379–385.Google Scholar
Panth, N, Gavarkovs, A, Tamez, M and Mattei, J (2018) The influence of diet on fertility and the implications for public health nutrition in the United States. Frontiers in Public Health 6, 211.CrossRefGoogle ScholarPubMed
Parappurathu, S, Kumar, A, Bantilan, MC and Joshi, PK (2015) Food consumption patterns and dietary diversity in eastern India: evidence from village-level studies (VLS). Food Security 7(5), 1031–1042.CrossRefGoogle Scholar
Rajan, A (2019) Type-1 diabetes mellitus and its relation with impairment of female fertility. Acta Scientific Nutritional Health 3(5), 210–214.Google Scholar
Ramachandran, N (2007) Women and food security in South Asia: current issues and emerging concerns. In Guha-Khasnobis, B, Acharya, SS and Davis, B (eds) Food Insecurity, Vulnerability and Human Rights Failure. Palgrave Macmillan, London, pp. 219–240.CrossRefGoogle Scholar
Rutstein, SO and Shah, IH (2004) Infecundity, infertility, and childlessness in developing countries. DHS Comparative Reports No. 9. URL: https://doi.org/PN-ADB-836.Google Scholar
Sabate, J (2014) Religion, diet and research. British Journal of Nutrition 92(2), 199–201.CrossRefGoogle Scholar
Sarkar, S and Gupta, P (2016) Socio-demographic correlates of women’s infertility and treatment seeking behavior in India. Journal of Reproduction and Infertility 17(2), 123–132.Google ScholarPubMed
Schmidt, M, Affenito, SG, Striegel-Moore, R, Khoury, PR, Barton, B et al (2005) Fast-food intake and diet quality in black and white girls: the National Heart, Lung, and Blood Institute Growth and Health Study. Archives of Pediatrics & Adolescent Medicine 159(7), 626–631.CrossRefGoogle ScholarPubMed
Sharma, R, Biedenharn, KR, Fedor, JM and Agarwal, A (2013) Lifestyle factors and reproductive health: taking control of your fertility. Reproductive Biology and Endocrinology 11(1), 66.CrossRefGoogle ScholarPubMed
Silvestris, E, de Pergola, G, Rosania, R and Loverro, G (2018) Obesity as disruptor of the female fertility. Reproductive Biology and Endocrinology 16(1), 1–13.CrossRefGoogle ScholarPubMed
Singh, P, Singh, S, Singh, R and Raghuvanshi, R (2006) Anaemia as a cause of infertility: focus on management of anaemia as first line management of infertility. Internet Journal of Gynecology and Obstetrics 8(1), https://doi.org/10.5580/24a5.CrossRefGoogle Scholar
Sridevi, N and Sandhya, RM (2015) Study of thyroid profile in infertile women. Journal of Pharmacy and Biological Sciences 10(3), 2319–7676.Google Scholar
Suocheng, W, Huining, L, Haoqin, L, Luju, L and Zhu, G (2016) Coca Cola and Pepsi Cola affect ovaries and follicles development. Biomedical Research 27(3), 710–717.Google Scholar
Syamala, TS (2012) Infertility in India: levels, trends, determinants and consequences. Working Paper No. 284, 2012, Copy, 1–25. Institute for Social and Economic Change, Bangalore. URL: http://www.isec.ac.in/WP%20284%20-%20T%20S%20Syamala.pdf Google Scholar
Szaboova, R and Devendra, S (2015) Infertility in a young woman with Type 2 diabetes. London Journal of Primary Care 7(3), 55–57.CrossRefGoogle Scholar
Tamang, JP (2016) Indian dietary culture. Journal of Ethnic Foods 4(3), 243–245.CrossRefGoogle Scholar
Unisa, S (1999) Childlessness in Andhra Pradesh, India: treatment-seeking and consequences. Reproductive Health Matters 7(13), 54–64.CrossRefGoogle Scholar
Unisa, S (2010) Infertility and treatment seeking in India: findings from district level household survey. Facts, Views and Vision in ObGyn, 59–65.Google Scholar
Vandermeersch, G, Lourenço, HM, Alvarez-Muñoz, D, Cunha, S, Diogène, J, Cano-Sancho, G et al. (2015) Environmental contaminants of emerging concern in seafood – European database on contaminant levels. Environmental Research 143, 29–45.CrossRefGoogle ScholarPubMed
Venkatesh, P, Sangeetha, V and Singh, P (2016) Relationship between food production and consumption diversity in India – empirical evidences from cross section analysis. Agricultural Economics Research Review 29, 139–148.CrossRefGoogle Scholar
Ventimiglia, E, Capogrosso, P, Boeri, L, Serino, A, Colicchia, M et al. (2015) Infertility as a proxy of general male health: results of a cross-sectional survey. Fertility and Sterility 104(1), 48–55.CrossRefGoogle ScholarPubMed
Verma, I, Sood, R, Juneja, S and Kaur, S (2012) Prevalence of hypothyroidism in infertile women and evaluation of response of treatment for hypothyroidism on infertility. International Journal of Applied and Basic Medical Research 2(1), 17.CrossRefGoogle ScholarPubMed
WHO (2004) Infecundity, Infertility, and Childlessness in Developing Countries. World Health Oragnization. URL: https://www.who.int/reproductivehealth/topics/infertility/DHS-CR9.pdf?ua=1.Google Scholar
WHO, UNICEF, UNFPA and WB (2012) Trends in Maternal Mortality: 1990 to 2010. WHO, Geneva. URL: https://apps.who.int/iris/bitstream/handle/10665/44874/9789241503631_eng.pdf;jsessionid=5549A315AF62D07DCE51CB94EE7DCD17?sequence=1 Google Scholar
Wills, W, Backett-Milburn, K, Roberts, ML and Lawton, J (2011) The framing of social class distinctions through family food and eating practices. The Sociological Review 59(4), 725–740.CrossRefGoogle Scholar