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ANALYSIS OF THE VIQ SCORES OF FAMILIES OF THREE OR MORE ORKNEY BROTHERS

Published online by Cambridge University Press:  04 April 2001

JOAN D. T. GOODMAN  and
R. B. ANDERTON
JOAN D. T. GOODMAN
Affiliation:
89 Rutherglen Road, Abbey Wood, London SE2 0XU
R. B. ANDERTON
Affiliation:
89 Rutherglen Road, Abbey Wood, London SE2 0XU
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Abstract

Classification of the boys in 48 families of three or more brothers according to their Moray House Test (VIQ) scores awarded at age 11±1½ years in 1947–75 confirms the postulated existence of a total of nine male phenotypes for this X-linked trait in the score range <70 to 140 points. The phenotypic means lie close to the sequence 69(8)133. Recombination is shown to occur. An additive effect of three alleles at each of two X-chromosome loci is the most likely simple scheme. An iterative approach matching the observed mixtures of proposed genotypes in the families with probabilities for variable levels of homozygosity, non-crossover/crossover heterozygosity, and maternal meiotic recombination yields a best goodness of fit where this last is 20%.

Type
Research Article
Information
Journal of Biosocial Science , Volume 29 , Issue 2 , April 1997 , pp. 181 - 190
Copyright
© 1997 Cambridge University Press

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