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Molecular genetic research on IQ: can it be done? Should it be done?

Published online by Cambridge University Press:  31 July 2008

Jo Daniels ,
Peter McGuffin  and
Mike Owen
Jo Daniels
Affiliation:
Division of Psychological Medicine, University of Wales College of Medicine, Heath Park, Cardiff CF4 4XN
Peter McGuffin
Affiliation:
Division of Psychological Medicine, University of Wales College of Medicine, Heath Park, Cardiff CF4 4XN
Mike Owen
Affiliation:
Division of Psychological Medicine, University of Wales College of Medicine, Heath Park, Cardiff CF4 4XN
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Extract

An obvious requirement before embarking on molecular genetic investigation of a trait is prior evidence from ‘classic’ genetic studies that there is indeed a genetic component. Many behavioural traits are familial and these range from comparatively uncommon single gene disorders such as Huntington's disease which has a typical mendelian dominant pattern of transmission, to much commoner characteristics such as career choice or religious denomination which, it might be assumed, are heavily influenced by cultural factors. In between, there is a wide range of attributes including personality type, cognitive ability and liability to common disorders such as depression, that show a tendency to run in families, and which could conceivably be explained by shared genes, shared environment or a combination of the two.

Type
Session 3: Genetic Issues
Information
Journal of Biosocial Science , Volume 28 , Special Issue 4: Proceedings of the Galton Institute Symposium on Biological and Social Aspects of Intelligence , October 1996 , pp. 490 - 507
Copyright
Copyright © Cambridge University Press 1996

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