Hostname: page-component-cd9895bd7-lnqnp Total loading time: 0 Render date: 2024-12-26T23:01:20.551Z Has data issue: false hasContentIssue false

A Central Limit Theorem for a Discrete-Time SIS Model with Individual Variation

Published online by Cambridge University Press:  04 February 2016

R. McVinish*
Affiliation:
University of Queensland
P. K. Pollett*
Affiliation:
University of Queensland
*
Postal address: School of Mathematics and Physics, University of Queensland, Brisbane, QLD 4072, Australia.
Postal address: School of Mathematics and Physics, University of Queensland, Brisbane, QLD 4072, Australia.
Rights & Permissions [Opens in a new window]

Abstract

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

A discrete-time SIS model is presented that allows individuals in the population to vary in terms of their susceptibility to infection and their rate of recovery. This model is a generalisation of the metapopulation model presented in McVinish and Pollett (2010). The main result of the paper is a central limit theorem showing that fluctuations in the proportion of infected individuals around the limiting proportion converges to a Gaussian random variable when appropriately rescaled. In contrast to the case where there is no variation amongst individuals, the limiting Gaussian distribution has a nonzero mean.

Type
Research Article
Copyright
© Applied Probability Trust 

References

Allen, L. J. S. and Burgin, A. M. (2000). Comparison of deterministic and stochastic SIS and SIR models in discrete time. Math. Biosci. 163, 133.Google Scholar
Buckley, F. M. and Pollett, P. K. (2010). Limit theorems for discrete-time metapopulation models. Prob. Surveys 7, 5383.CrossRefGoogle Scholar
Gani, J., Yakowitz, Y. and Blount, M. (1997). The spread and quarantine of HIV infection in a prison system. SIAM J. Appl. Math. 57, 15101530.CrossRefGoogle Scholar
Lekone, P. E. and Finkenstädt, B. F. (2006). Statistical inference in a stochastic epidemic SEIR model with control intervention: Ebola as a case study. Biometrics 62, 11701177.Google Scholar
McVinish, R. and Pollett, P. K. (2010). Limits of large metapopulations with patch-dependent extinction probabilities. Adv. Appl. Prob. 42, 11721186.Google Scholar
Tuckwell, H. C. and Williams, R. J. (2007). Some properties of a simple stochastic epidemic model of SIR type. Math. Biosci. 208, 7697.Google Scholar