Hostname: page-component-7bb8b95d7b-dvmhs Total loading time: 0 Render date: 2024-09-07T04:48:17.061Z Has data issue: false hasContentIssue false
  • English
  • Français

Thyroid metabolism in sheep during pregnancy

Published online by Cambridge University Press:  27 March 2009

E. F. Annison  and
D. Lewis
E. F. Annison
Affiliation:
A.R.C. Institute of Animal Physiology, Babrdham, Cambridge
D. Lewis
Affiliation:
A.R.C. Institute of Animal Physiology, Babrdham, Cambridge
Get access Rights & Permissions [Opens in a new window]

Extract

1. The peripheral metabolism of thyroxine in sheep in pregnancy was investigated by measuring the rate of disappearance from blood of injected 131I-thyroxine. Only limited changes in thyroid metabolism during pregnancy were observed. The rate of turnover of thyroxine slightly increased, but this was not accompanied by increased levels of plasma protein-bound iodine (PBI), or thyroxinebinding protein.

2. In a 3·5-month foetus, the thyroid was active, and a marked concentration of iodide by the foetus was observed. The significance of this activity could not be assessed in the absence of knowledge on the placental passage of iodide or thyroxine in the sheep.

3. Knowledge of thyroid metabolism is inadequate at present to explain any correlation between animal productivity and either hormone supplementation, or PBI concentration.

Type
Research Article
Information
The Journal of Agricultural Science , Volume 52 , Issue 1 , February 1959 , pp. 79 - 86
Copyright
Copyright © Cambridge University Press 1959

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

REFERENCES

Annison, E. F. & Lewis, D. (1958). Biochem. J. 68, 29 P.Google Scholar
Barker, S. B. (1951). Pkysiol. Rev. 31, 205.CrossRefGoogle Scholar
Barker, S. B., Humphrey, M. J. & Soley, M. H. (1951). J. Clin. Invest. 30, 55.CrossRefGoogle Scholar
Barnes, C. M., Warmer, D. E., Marks, S. & Bustad, L. K. (1957). Endocrinology, 60, 327.CrossRefGoogle Scholar
Blaxter, K. L. (1945). J. Endocrinol. 4, 237.CrossRefGoogle Scholar
Bronk, J. R. (1958). Biochim. biophys. Acta, 27, 668.Google Scholar
Burns, K. H., Colby, R. W., Gougler, P. & Kunkel, H. O. (1953). Amer. J. Physiol. 172, 107.CrossRefGoogle Scholar
Burwell, C. S. (1954). Johns Hopk. Hosp. Bull. 95, 115.Google Scholar
Dempsey, E. W. & Astwood, E. B. (1943). Endocrinology, 32, 509.CrossRefGoogle Scholar
Fenger, F. (1912). J. Biol. Chem. 12, 55.CrossRefGoogle Scholar
Ferraris, G. M. & Scorta, A. (1955). Minerva ginec. 7, 308.Google Scholar
Freedberg, I. M., Hamolsky, M. W. & Freedberg, A. S. (1957). New Engl. J. Med. 256, 505, 551.CrossRefGoogle Scholar
Freinkel, N. & Lewis, D. (1957). J. Physiol. 135, 288.CrossRefGoogle Scholar
Gorbman, A., Waterman, A., Barnes, C. M. & Bustad, L. K. (1957). Endocrinology, 60, 565.CrossRefGoogle Scholar
Grumbach, M. M. & Werner, S. C. (1956). J. Clin. Endocrin. 16, 1393.CrossRefGoogle Scholar
Hall, P. F. & Myant, N. B. (1956). J. Physiol. 133, 181.CrossRefGoogle Scholar
Hart, D. S. (1954). Nature, Lond., 174, 1018.CrossRefGoogle Scholar
Heinemann, M., Johnson, C. E. & Man, E. B. (1948). J. Clin. Invest. 27, 91.CrossRefGoogle Scholar
Henneman, H. A., Reineke, E. P. & Griffin, S. A. (1955). J. Anim. Sci. 14, 419.CrossRefGoogle Scholar
Hodges, R. E., Evans, T. C., Bradbury, J. T. & Keitel, W. C. (1955). J. Clin. Endocrin. 15, 661.CrossRefGoogle Scholar
Hogben, L. T. & Crewe, F. A. E. (1924). Brit. J. Exp. Biol. 1, 1.Google Scholar
Ingbar, S. H. & Freinkel, N. (1955). J. Clin. Invest. 34, 808.CrossRefGoogle Scholar
Kunkel, H. O., Colby, R. W. & Lyman, C. M. (1953). J. Anim. Sci. 12, 3.CrossRefGoogle Scholar
Lewis, R. C. & Ralston, N. P. (1953). J. Dairy Sci. 36, 33.CrossRefGoogle Scholar
Lodge, D. R., Lewis, R. C. & Reineke, E. P. (1957). J. Dairy Sci. 40, 209.CrossRefGoogle Scholar
Long, J. F., Gilmore, L. D., Curtis, G. H. & Rife, D. C. (1952). J. Dairy Sci. 35, 603.CrossRefGoogle Scholar
Magnus-Levy, W. (1897). Cited by Soule S. D. (1932). Amer. J. Obstet. Gynec. 23, 165.Google Scholar
Pochin, E. F. (1952). Clin. Sci. 11, 441.Google Scholar
Schultz, A. B. & Turner, C. W. (1945). Res. Bull. Univ. Mo. Coll. Agric. Exp. Sta. no. 392.Google Scholar
Singh, D. N., Henneman, H. A. & Reineke, E. P. (1956). J. Anim. Sci. 15, 625.CrossRefGoogle Scholar
Sørensen, P. H. (1956). Yearbook Royal Vet. Agric. Coll. Copenhagen, Denmark, pp. 64–76.Google Scholar
Swanson, E. W., Lengemann, F. W. & Monroe, R. A. (1957). J. Anim. Sci. 16, 318.CrossRefGoogle Scholar
Taurog, A., Chaikoff, I. L. & Entenmann, C. (1947). Endocrinology, 40, 86.CrossRefGoogle Scholar