Hostname: page-component-586b7cd67f-dlnhk Total loading time: 0 Render date: 2024-11-27T16:58:07.176Z Has data issue: false hasContentIssue false
  • English
  • Français

Studies of the skeleton of the sheep I. The effect of different levels of dietary calcium during pregnancy and lactation on individual bones

Published online by Cambridge University Press:  27 March 2009

D. Benzie ,
A. W. Boyne ,
A. C. Dalgarno ,
J. Duckworth ,
R. Hill  and
D. M. Walker
D. Benzie
Affiliation:
The Rowett Research Institute, Aberdeen, Scotland
A. W. Boyne
Affiliation:
The Rowett Research Institute, Aberdeen, Scotland
A. C. Dalgarno
Affiliation:
The Rowett Research Institute, Aberdeen, Scotland
J. Duckworth
Affiliation:
The Rowett Research Institute, Aberdeen, Scotland
R. Hill
Affiliation:
The Rowett Research Institute, Aberdeen, Scotland
D. M. Walker
Affiliation:
The Rowett Research Institute, Aberdeen, Scotland
Get access Rights & Permissions [Opens in a new window]

Extract

1. Three groups of mature ewes were fed during pregnancy and lactation on rations differing in their calcium content. The mean daily intakes of calcium were 1·4 g. (group A), 4·5 g. (group B), and 7·4 g. (group C). Blood samples were analysed monthly for calcium and inorganic phosphorus. The ewes were killed at approximately 100 days after parturition and the skeletons isolated. Individual bones, either whole or divided into definite fractions, were analysed.

2. The level of calcium intake was without effect on the number of lambs born, birth weight, or growth while milk fed.

3. Blood calcium was significantly lower in group A than in groups B and C, but blood inorganic phosphorus was unaltered.

4. The resorption of bone substance was greater in group A than in groups B and C.

5. The severity of resorption varied between bones, and in regions within certain bones. Resorption was most severe in the vertebrae and pelvis, and only slight in the metacarpal, the metatarsal and the shafts of other long bones. Resorption of intermediate magnitude was found for the remainder of the skeleton.

6. Resorption was accompanied by reductions in the percentages of ash in bones, but this effect was proportionately less than the ash weight reduction.

7. Radiological observations made on flesh-free bones at the end of the experiment gave a picture of resorption similar to that presented by the data for ash weights and percentages of ash, namely that resorption was much greater in group A than in groups B and C.

Type
Research Article
Information
The Journal of Agricultural Science , Volume 46 , Issue 4 , November 1955 , pp. 425 - 440
Copyright
Copyright © Cambridge University Press 1955

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

REFERENCES

Albright, F. & Reifenstein, E. C. (1948). The Parathyroid Glands and Metabolic Bone Disease. Baltimore: Williams and Wilkins.Google Scholar
Baker, S. L., Butterworth, E. C. & Langley, F. A. (1946). Biochem. J. 40, 391.CrossRefGoogle Scholar
Bauer, W., Aub, J. C. & Albright, F. (1929). J. Exp. Med. 49, 145.CrossRefGoogle Scholar
Baxter, J. H., van Dyk, J. J. & Follis, R. H. (1953). Johns Hopk. Hosp. Bull. 93, 25.Google Scholar
Clark, E. P. & Collip, J. B. (1925). J. Biol. Chem. 63, 461.CrossRefGoogle Scholar
Duckworth, J. & Hill, R. (1953). Nutr. Abstr. Rev. 23, 1.Google Scholar
Ellinger, G. M., Duckworth, J., Dalgarno, A. C. & Quenouille, M. H. (1952). Brit. J. Nutr. 6, 235.CrossRefGoogle Scholar
Fiske, C. H. & Subbarow, Y. (1925). J. Biol. Chem. 66, 375.CrossRefGoogle Scholar
Fraser, A. H. H. (1939). Trans. Highl. Agric. Soc. Scot. 51, 39.Google Scholar
McLean, F. C. & Bloom, W. (1940). Anat. Rec. 78, 333.CrossRefGoogle Scholar
McLean, F. C. & Bloom, W. (1941). Arch- Path. (Lab. Med.) 32, 315.Google Scholar
Meulengracht, E. (1939 a). Acta med. scand. 101, 138.CrossRefGoogle Scholar
Meulengracht, E. (1939 b). Acta med. scand. 101, 157.CrossRefGoogle Scholar
Meulengracht, E. (1939 c). Acta med. scand. 101, 187.CrossRefGoogle Scholar
Mills, C. (1953). Chem. & Ind. p. 330.Google Scholar
Rogers, H. J., Weidmann, S. M. & Jones, H. G. (1953). Biochem. J. 54, 37.CrossRefGoogle Scholar
Theiler, A. & Green, H. H. (1931–1932). Nutr. Abstr. Rev. 1, 359.Google Scholar
Thomson, W. & Thomson, A. M. (1953). Brit. J. Nutr. 7, 263.CrossRefGoogle Scholar
Warnock, G. M. & Duckworth, J. (1944). Biochem. J. 38, 220.CrossRefGoogle Scholar