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Incorporation of abomasal and intravenous doses of [35S]cystine and [35S]methionine into wool

Published online by Cambridge University Press:  27 March 2009

P. J. Reis ,
D. A. Tunks  and
L. F. Sharry
P. J. Reis
Affiliation:
CSIRO, Division of Animal Production, Ian Clunies Ross Animal Research LaboratoryP.O. Box 239BlacktownNSW 2148Australia
D. A. Tunks
Affiliation:
CSIRO, Division of Animal Production, Ian Clunies Ross Animal Research LaboratoryP.O. Box 239BlacktownNSW 2148Australia
L. F. Sharry
Affiliation:
CSIRO, Division of Animal Production, Ian Clunies Ross Animal Research LaboratoryP.O. Box 239BlacktownNSW 2148Australia
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Summary

The fate of abomasal and intravenous doses of [35S]cystine and [35S]methionine was investigated in sheep to determine their relative efficacy as supplements for wool growth.

Administration of L-[35S]cystine and L-, DL- and D-[35S]methionine via the abomasum produced similar patterns of 35S labelling in blood plasma. Only 10–16% of the administered 35S was excreted in urine over 7 days and 22–32% of the dose was incorporated into wool over 21 days. All isomers were utilized by the sheep with similar efficiency and it was concluded that D- and L-methionine and L-cystine are equally effective as supplements for wool growth at optimal dose rates. Abomasal supplementation with a large amount of methionine (10 g/day) resulted in the excretion of a high proportion of the 35S in urine (55% of the dose over 7 days) and low incorporation into wool.

A comparison of the extent of incorporation of 35S into wool from intravenous doses of L-[35S]cystine and L-[35S]methionine in the same sheep, and in sheep from flocks selected for high and low wool production, showed that incorporation from methionine averaged 80% of that from cystine. It was concluded that, at moderate (2–3 g/day) methionine availability, methionine is utilized for synthesis of wool with about 80% of the efficiency of cystine, conversion of methionine to cysteine occurring via the transulphuration pathway.

Type
Review
Information
The Journal of Agricultural Science , Volume 112 , Issue 3 , June 1989 , pp. 313 - 319
Copyright
Copyright © Cambridge University Press 1989

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