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Hepatic xanthine dehydrogenase and plasma uric acid in broiler chickens fed various amounts of dietary methionine, protein and energy

Published online by Cambridge University Press:  27 March 2009

F. O. Amubode  and
B. L. Fetuga
F. O. Amubode
Affiliation:
Department of Animal Science, University of Ibadan, Nigeria
B. L. Fetuga
Affiliation:
Department of Animal Science, University of Ibadan, Nigeria
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Summary

In four consecutive experiments, plasma uric acid (PUA), hepatic xanthine dehydrogenase (XDH) and body-weight gains (WG) of broiler chickens were measured under varying dietary methionine, protein and energy. In Expt 1, increases in WG with increasing dietary methionine peaked at 0·60%, a level where the initial decreases in either PUA or XDH reached a minimum. PUA and XDH in broiler finishers (Expt 2) decreased between 0·26 and 0·50% dietary methionine while WG improved between 0·26 and 0·50% methionine. XDH in the 18% protein and 0·68% methionine + cystine (MC) diet combination for Expt 3 was 66·4 μtmol/10 min/total liver weight, a value higher than either the 43·5 or 46·5 μtmol/10 min/total liver weight, respectively obtained in the 21% protein + 0·68% MC and 24% protein + 0·68% MC diet combinations. Both PUA and XDH, however, increased with increasing dietary protein when MC was either 0·76 or 0·84% diet. XDH in Expt 4 decreased between 11·7 and 13·4 MJ ME/kg diet that contained either 0·76 or 0·84% MC, tending not to vary between 13·4 and 15·1 MJ ME/kg diet. This enzyme activity remained essentially similar between 11·7 and 15·1 MJ ME/kg diet that contained 0·68% MC.

Type
Research Article
Information
The Journal of Agricultural Science , Volume 103 , Issue 3 , December 1984 , pp. 497 - 502
Copyright
Copyright © Cambridge University Press 1984

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