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The effect of dietary molybdenum and iron on copper status and growth in cattle

Published online by Cambridge University Press:  27 March 2009

M. Phillippo ,
W. R. Humphries  and
P. H. Garthwaite
M. Phillippo
Affiliation:
Rowett Research InstituteBucksburn, Aberdeen, AB2 9SB
W. R. Humphries
Affiliation:
Rowett Research InstituteBucksburn, Aberdeen, AB2 9SB
P. H. Garthwaite
Affiliation:
University of AberdeenAberdeen, AB9 1FX
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Summary

The effects of supplementation of a barley-barley straw diet containing 4 mg copper (Cu)/kg dry matter (D.M.) either with 5 mg molybdenum (Mo)/kg D.M. or with 500 mg iron (Fe)/kg D.M. on the Cu status, growth and clinical condition of calves are described. Liver and plasma Cu concentrations declined rapidly within 12–16 weeks to levels indicating severe Cu deficiency in both the Mo- and Fe-supplemented groups. The changes in Cu status were similar for both supplements and did not differ significantly from each other. Clinical signs of Cu deficiency, as indicated by reduced growth rate and changes in hair texture and colour, were evident after 16–20 weeks only in animals on the Mosupplemented diet. The reduced growth rate was accompanied by a decreased food intake and reduced efficiency of food utilization. The Mo-supplemented animals also exhibited an altered Fe metabolism, particularly when the growth rate was affected. The results confirm earlier reports that the effects of Mo on growth and clinical condition are independent of its effect on Cu status and suggest that the altered production might be due to effects on the control of food intake, food utilization, or Fe metabolism.

Type
Research Article
Information
The Journal of Agricultural Science , Volume 109 , Issue 2 , October 1987 , pp. 315 - 320
Copyright
Copyright © Cambridge University Press 1987

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References

Bennetts, H. W., Beck, A. B. & Hartley, R. (1948). The pathogenesis of ‘falling disease’ Studies on copper deficiency in cattle. Australian Veterinary Journal 24, 237–244.CrossRefGoogle Scholar
Bingley, J. B. (1959). Simplified determination of molybdenum in plant material by 4-methly-1, 2-dimercaptobenzone, dithiol. Journal of Agricultural and Food Chemistry 7, 269–270.CrossRefGoogle Scholar
Boyne, R. & Arthur, J. R. (1986). Effects of molybdenum or iron induced copper deficiency on the viability and function of neufcrophils in cattle. Research in Veterinary Science 41, 417–419.CrossRefGoogle ScholarPubMed
Campbell, A. G., Coup, M. R., Bishop, W. H. & Wright, D. E. (1974). Effect of elevated iron intake on the copper status of grazing cattle. New Zealand Journal of Agricultural Research 17, 393–399.CrossRefGoogle Scholar
Coup, M. R. & Campbell, A. C. (1964). Effect of excessive iron intake upon the health and production of dairy cows. New Zealand Journal of Agricultural Research 7, 624–638.CrossRefGoogle Scholar
Fell, B. F., Farmer, L. J., Farquharson, C., Bremner, I. & Graca, D. S. (1985). Observations on the pancreas of cattle deficient in copper. Journal of Comparative Pathology 95, 573–590.CrossRefGoogle ScholarPubMed
Humphries, W. R., Bremner, I. & Phillippo, M. (1985). The influence of dietary iron on copper metabolism in the calf. In Trace Elements in Man and Animals Vol. 5 (ed. Mills, C. F., Bremner, I., J. K. and Chesters, ), pp. 371–374. Slough: Commonwealth Agricultural Bureaux.Google Scholar
Humphries, W. R., Phillippo, M., Young, B. W. & Bremner, I. (1983). The influence of dietary iron and molybdenum on copper metabolism in calves. British Journal of Nutrition 49, 77–83.CrossRefGoogle ScholarPubMed
Lesperance, A. L. (1974). Effect of molybdenum, sulfate and alfalfa in the bovine. Ph.D. thesis, Oregon State University.Google Scholar
Loosmore, R. M. & Allcroft, R. (1951). Technique and use of liver biopsy in cattle. Veterinary Record 63, 414–416.Google Scholar
Mills, C. F. (1980). Metabolic interactions of copper with other trace elements. In Biological Roles of Copper. CIBA Foundation Symposium 79, pp. 49–65. Amsterdam: Excerpta Medica.CrossRefGoogle Scholar
Mills, C. F., Dalgarno, A. C., Bremner, I. & El-Gallad, T. T. (1977). Influence of the dietary content of molybdenum and sulphur upon hepatic retention of copper in young cattle. Proceedings of the Nutrition Society 36, 105A.Google ScholarPubMed
Mills, C. F., Dalgarno, A. C. & Wenham, G. (1975). Biochemical and pathological changes in tissues of Friesian cattle during the experimental induction of copper deficiency. British Journal of Nutrition 35, 309–331.CrossRefGoogle Scholar
Phillippo, M. (1983). The role of dose-response trials in predicting trace element deficiency disorders. In Trace Elements in Animal Production and Veterinary Practice (ed. Suttle, N. F.Gunn, R. G.Allen, W. M.Linklater, K. A. and Wiener, G.), pp. 51–59. Occasional publication of the British Society for Animal Production.Google Scholar
Phillippo, M., Humphries, W. R., Atkinson, T., Henderson, G. D. & Garthwaite, P. H. (1987). The effect of dietary molybdenum and iron on copper status, puberty, fertility and oestrous cycles in cattle. Journal of Agricultural Science, Cambridge 109, 321–336.CrossRefGoogle Scholar
Quin, B. F. & Woods, P. H. (1979). Automated catalytic method for the routine determination of molybdenum in plant materials. Analyst, London 104, 552–559.CrossRefGoogle Scholar
Smith, B. P., Fisher, G. L., Poulos, P. W. & Irwin, M. R. (1975). Abnormal bone development and lameness associated with secondary copper deficiency in young cattle. Journal of the American Veterinary Medical Association 166, 682–688.Google ScholarPubMed
Standish, J. F., Ammerman, C. B., Palmer, A. Z. & Simpson, C. F. (1971). Influence of dietary iron and phosphorus on performance, tissue mineral composition and mineral absorption in steers. Journal of Animal Science 33, 171–178.CrossRefGoogle ScholarPubMed
Standish, J. F., Ammerman, C. B., Simpson, C. F., Neal, F. C. & Palmer, A. Z. (1969). Influence of graded levels of dietary iron, as ferrous sulfate, on performance and tissue mineral composition of steers. Journal of Animal Science 29, 496–503.CrossRefGoogle ScholarPubMed