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A relationship between thyroid activity, acetate infusion and food intake in rams
Published online by Cambridge University Press: 27 March 2009
Summary
Six mature rams were used in a 6 × 6 latin square experiment. They were put on a high concentrate ad lib. diet. Voluntary food intake was measured on the rams which received the following treatments: control, thiouracil, sodium acetate, thyroxine, sodium acetate plus thiouracil and sodium acetate plus thyroxine. Acetate was infused intraruminally at the level of 6·2 g/kg W0·75 per day for 4 successive days. Thyroxine was injected subcutaneously at the level of 0·3, 0·6, 0·9 and 0·9 mg/kg W0·75/day successively. Thiouracil was given orally as the propionyl derivative at a level of 0·03, 0·06, 0·06 and 0·06 g/kg W0·75/day successively.
Respiration rate, pulse rate and rectal temperature were measured before and 1 h after dosing. A period of at least 25 days was allowed between the trials. All the results were calculated as feed intake (g dry matter)/kg W0·75.
Injection of thyroxine, sodium acetate and both together inhibited food intake significantly. Thiouracil showed no significant effect on feed intake but it relieved part of the depression caused by acetate. Pulse rate showed significant differences between treatments but rectal temperature and respiration rate did not change significantly. The results are discussed in the text.
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- Copyright © Cambridge University Press 1972