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Wernicke-Korsakoff syndrome following self-induced starvation

Published online by Cambridge University Press:  13 June 2014

Dinesh K Arya
Dinesh K Arya*
Affiliation:
Department of Psychiatry, Peter Hodgkinson Centre, County Hospital, Lincoln, LN2 5QY, England
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Abstract

A non-alcoholic patient is reported who as a result of self-induced starvation was found to have nystagmus, gait ataxia and severe deficits in recent and remote memory and new learning, with intact immediate recall, abstraction and judgement capabilities. This pattern of cognitive deficit with nystagmus and ataxia suggests the diagnosis of Wernicke-Korsakoff syndrome.

Keywords

Korsakoff'sPsychosisStarvationWernicke's
Type
Clinical and Brief Reports
Information
Irish Journal of Psychological Medicine , Volume 12 , Issue 2 , June 1995 , pp. 66 - 67
Copyright
Copyright © Cambridge University Press 1995

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References

1.Victor, M, Adams, RD, Collins, GH. The Wernicke-Korsakoff syndrome. Oxford: Blackwell Scientific Publications, 1971.Google ScholarPubMed
2.De Wardener, HE, Lennox, B. Cerebral beriberi (Wernicke's encephalopathy). Lancet 1947; i: 11.CrossRefGoogle Scholar
3.Malamud, N, Skillicorn, SA. Relationship between the Wernicke and Korsakoff syndromes. Arch Neurol Psychiatr 1956; 76: 585–96.CrossRefGoogle Scholar
4.Lishman, WA. Alcohol and the brain. Br J Psychiatry 1990; 156: 635–44.CrossRefGoogle ScholarPubMed
5.Campbell, ACP, Russell, WR. Wernicke's encephalopathy: the clinical features and their probable relationship to vitamin B deficiency. Quart J Med 1947; 34: 41–64.Google Scholar
6.Rimalovski, AB, Aronson, SM. Pathogenic observations in Wernicke-Korsakoff encephalopathy. Trans Am Neurol Assoc 1966; 91: 29–31.Google Scholar
7.Cruickshank, EK. Wernicke's encephalopathy. Quart J Med 1950; 19: 327Google ScholarPubMed
8.Falzi, G, Ronchi, G. Wernicke's lethal encephalopathy in voluntary, total, prolonged fasting. Forensic Science International 1990; 47: 17–20.CrossRefGoogle ScholarPubMed
9.Handler, CE, Perkin, GD. Anorexia nervosa and Wernicke's encephalopathy: an undiagnosed association. Lancet 1982; ii: 771–2.CrossRefGoogle Scholar
10.Drenick, EJ, Joven, CB, Swendseid, MD. Occurrence of acute Wernicke's encephalopathy during prolonged starvation for the treatment of obesity. New Engl J Med 1967: 274:937.CrossRefGoogle Scholar
11.Frantzen, E. Wernicke's encephalopathy: three cases occurring in connection with severe malnutrition. Acta Neurologica Scandinavica 1966; 42:426.CrossRefGoogle Scholar
12.Wallis, WE, Willoughby, E, Baker, P. Coma in the Wernicke-Korsakoff syndrome. Lancet 1978; ii: 400.CrossRefGoogle Scholar
13.Clinico-pathological Conference. Two geriatric cases. BMJ 1979; 1: 1768.CrossRefGoogle Scholar
14.Pentland, B, Mawdsley, C. Wernicke's encephalopathy following ‘hunger strike’. Post Med J 1982;58:427–8.CrossRefGoogle ScholarPubMed
15.Parkin, AJ, Blunden, J, Rees, JE, et al.Wernicke-Korsakoff syndrome of non-alcoholic origin. Brain and Cognition 1991; 15: 69–82.CrossRefGoogle Scholar
16.Engel, PA, Grunnet, M, Jacobs, B. Wernicke-Korsakoff syndrome complicating T-cell Lymphoma: unusual or unrecognised? Southern Medical Journal 1991; 84: 253–6.CrossRefGoogle ScholarPubMed
17.Jolliffe, N. Treatment of neuropsychiatric disorders with vitamins. J Am Med Assoc 1941; 117: 1496–500.CrossRefGoogle Scholar
18.Bowman, KM, Goodhart, R, Jolliffe, N. Observations on the role of vitamin B1 in the aetiology and treatment of Korsakoff psychosis. J Nerv Ment Dis 1939; 90: 569–75.CrossRefGoogle Scholar
19.Freund, G. Chronic central nervous system toxicity of alcohol. Ann Rev Pharmacol 1973; 13:217–27.CrossRefGoogle ScholarPubMed
20.Lishman, WA. Vitamin deficiencies, in organic psychiatry. 2nd Ed. Oxford: Blackwell Scientific Publications, 1987.Google Scholar