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Situational and psycho-social factors associated with relapse following residential detoxification in a population of Irish opioid dependent patients

Published online by Cambridge University Press:  13 June 2014

Kevin Ducray*
Affiliation:
The Drug Treatment Centre Board, 30-31 Pearse Street, Dublin 2, Ireland
Catherine Darker
Affiliation:
Department of Public Health and Primary Care, Trinity College, Dublin 2, Ireland
Bobby P Smyth
Affiliation:
The Drug Treatment Centre Board, 30-31 Pearse Street, Dublin 2, Ireland Department of Public Health and Primary Care, Trinity College, Dublin 2, Ireland
*
*Correspondence E-mail: [email protected]

Abstract

Aims: To identify and describe the context and factors involved in the opioid lapse process following discharge from an Irish inpatient opioid detoxification treatment programme.

Design, participants, setting: Prospective follow-up study of consecutive detoxified opioid dependent patients treated in a specialist inpatient drug dependency unit.

Measurements: The Maudsley Addiction Profile and a structured interview were administered to 109 patients, 18–36 months after discharge.

Findings: Of 109 people interviewed at follow-up, 102 (94%) reported at least one episode of opioid use after leaving the residential treatment programme. Eighty eight patients (86% of the lapsers) identified more than one major factor contributing to their recidivism. The median number of factors identified as having a major role in the lapse was four. The most frequently reported major contributors to lapse were low mood (62%), difficulties with craving (62%), ease of access to heroin (48%) and missing the support of the treatment centre (43%).

Conclusions: Early lapse was common following inpatient treatment of opioid dependence. Lapse tended to result from a number of common, identifiable, high-risk situations, feelings and cognitions which may assist clinicians and patients develop lapse prevention strategies to anticipate and interrupt this process.

Type
Original Paper
Copyright
Copyright © Cambridge University Press 2012

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References

1.Comiskey, C, Cox, G. ROSIE baseline data report. Dublin: National Advisory Committee on Drugs; 2007.Google Scholar
2.Callon, C, Wood, E, Marsh, D, Li, K, Montaner, J, Kerr, T. Barriers and facilitators to methadone maintenance therapy use among illicit opiate injection drug users in Vancouver. J Opioid Manag 2006 01-Feb; 2(1):3541.CrossRefGoogle Scholar
3.Marsch, LA. The efficacy of methadone maintenance interventions in reducing illicit opiate use, HIV risk behavior and criminality: a meta-analysis. Addiction 1998 Apr; 93(4):515–32.CrossRefGoogle ScholarPubMed
4.McKeganey, N. The challenge to UK drug policy. Drug-Educ Prev Policy 2007; 14 (6):559571.CrossRefGoogle Scholar
5.Hubbard, RL, Craddock, SG, Anderson, J. Overview of 5-year follow up outcomes in the drug abuse treatment outcome studies (DATOS). J Subst Abuse Treat 2003 10; 25(3):125–34.CrossRefGoogle ScholarPubMed
6.Strang, J, McCambridge, J, Best, D, Beswick, T, Bearn, J, Rees, S, Gossop, M. Loss of tolerance and overdose mortality after inpatient opiate detoxification: follow up study. BMJ 2003 05; 326(7396):959–60.CrossRefGoogle ScholarPubMed
7.Day, E. Opiate detoxification in an inpatient setting. London: National Treatment Agency for Substance Misuse, 2005.Google Scholar
8.Comptroller Auditor General VFM Report 64. Drug Addiction Treatment & Rehabilitation. Dublin: Office of the Comptroller Auditor General, 2009.Google Scholar
9.Farrell, M, Barry, J. The introduction of the opioid treatment protocol. Dublin: Health Service Executive, 2010.Google Scholar
10.Van den Brink, W, Haasen, C. Evidence-based treatment of opioid-dependent patients. Can J Psychiatry 2006 09; 51 (10): 635–46.CrossRefGoogle ScholarPubMed
11.National Drugs Strategy 20012008: Building on Experience. Dublin: Department of Tourism, Sport and Recreation, 2001.Google Scholar
12.National Drugs Strategy (interim) 2009-2016. Dublin: Department of Community, Rural and Gaeltacht Affairs, 2009.Google Scholar
13.Haug, NA, Sorensen, JL, Gruber, VA, Song, JS. Relapse prevention for opioid dependence. In: Marlatt, GA, Donovan, DM, editors. Relapse Prevention. 2nd ed. New York: Guilford Press; 2005. P 151–78.Google Scholar
14.Witkiewitz, K, Marlatt, GA. Modeling the complexity of post-treatment drinking: it's a rocky road to relapse. Clin Psychol Rev 2007 07; 27(6):724–38.CrossRefGoogle ScholarPubMed
15.Ockene, JK, Emmons, KM, Mermelstein, RJ, Perkins, KA, Bonollo, DS, Voorhees, CC, Hollis, JF. Relapse and maintenance issues for smoking cessation. Health Psychol 2000 01; 19(1 Suppl):1731.CrossRefGoogle ScholarPubMed
16.Litman, GK, Stapleton, J, Oppenheim, AN, Peleg, M, Jackson, P. Situations related to alcoholism relapse. Br J Addict 1983 12; 78(4):381–9.CrossRefGoogle ScholarPubMed
17.Amato, L, Minozzi, S, Davoli, M, Vecchi, S, Ferri, M, Mayet, S. Psychosocial and pharmacological treatments versus pharmacological treatments for opioid detoxification. Cochrane Database Syst Rev 2008 10; (4): CD005031. Review.Google Scholar
18.Fugelstad, A, Stenbacka, M, Leifman, A, Nylander, M and Thiblin, I. Methadone maintenance treatment: the balance between life-saving treatment and fatal poisonings. Addiction 2007; 102(3): 406412.CrossRefGoogle ScholarPubMed
19.Naderi-Heiden, A, Gleiss, A, Bäcker, C, Bieber, D, Nassan-Agha, H, Kasper, S, Frey, R. Mortality and employment after in-patient opiate detoxification. European Psychiatry: the journal of the Association of European Psychiatrists 2010 07: 0924-9338.Google ScholarPubMed
20.Marlatt, GA. Relapse Prevention: Theoretical rational and overview of the model. In: Marlatt, GA, Gordon, JR, editors. Relapse Prevention: Maintenance Strategies in the Treatment of Addictive Behaviors. New York: Guilford Press; 1985. p 370.Google Scholar
21.Donovan, DM. Assessment of addictive behaviors for relapse prevention. In: Donovan, DM, Marlatt, GA, editors. Assessment of addictive behaviors. New York: Guilford Press; 2005. p 148.Google Scholar
22.Shiffman, S. Conceptual issues in the study of relapse. In: Gossop, M, editor. Relapse and addictive behaviour. London: Routledge; 1989. p 149–79.Google Scholar
23.Donovan, DM. Marlatt's classification of relapse precipitants: is the Emperor still wearing clothes?Addiction 1996 12; 91 Suppl: S131–7.Google Scholar
24.Witkiewitz, K, Marlatt, GA. Relapse prevention for alcohol and drug problems: that was Zen, this is Tao. Am Psychol 2004 05-Jun; 59(4):224–35.CrossRefGoogle ScholarPubMed
25.Hunter-Reel, D, McCrady, B, Hildebrandt, T. Emphasizing interpersonal factors: an extension of the Witkiewitz and Marlatt relapse model. Addiction 2009; 104: 12811290.CrossRefGoogle ScholarPubMed
26.Bradley, BP, Phillips, G, Green, L, Gossop, M. Circumstances surrounding the initial lapse to opiate use following detoxification. Br J Psychiatry 1989 03; 154: 354–9.CrossRefGoogle ScholarPubMed
27.Westermeyer, J. Nontreatment factors affecting treatment outcome in substance abuse. Am J Drug Alcohol Abuse 1989; 15(1): 1329.CrossRefGoogle ScholarPubMed
28.Gossop, M, Green, L, Phillips, G, Bradley, B. Lapse, relapse and survival among opiate addicts after treatment. A prospective follow-up study. Br J Psychiatry 1989 03; 154: 348–53.CrossRefGoogle ScholarPubMed
29.Unnithan, S, Gossop, M, Strang, J. Factors associated with relapse among opiate addicts in an out-patient detoxification programme. Br J Psychiatry 1992 11; 161: 654–7.CrossRefGoogle Scholar
30.Heather, N, Stallard, A, Tebbutt, J. Importance of substance cues in relapse among heroin users: comparison of two methods of investigation. Addict Behav 1991; 16(1–2): 41–9.CrossRefGoogle ScholarPubMed
31.Maulik, PK, Tripathi, BM, Pal, HR. Coping behaviors and relapse precipitants in opioid dependence: a study from North India. J Subst Abuse Treat 2002 04; 22(3): 135–40.CrossRefGoogle ScholarPubMed
32.Westphal, J, Wasserman, DA, Masson, CL, Sorenson, JL. Assessment of opioid use. In: Donovan, DM, Marlatt, GA, editors. Assessment of addictive behaviours. 2nd ed. New York: Guilford; 2005. p 215–47.Google Scholar
33.Smyth, BP, Barry, J, Lane, A, Cotter, M, O'Neill, M, Quinn, C, Keenan, E. In-patient treatment of opiate dependence: medium-term follow-up outcomes. Br J Psychiatry 2005 10; 187:360–5.CrossRefGoogle ScholarPubMed
34.Smyth, BP, Barry, J, Keenan, E, Ducray, K. Lapse and Relapse Following Inpatient Treatment of Opiate Dependence, IMJ 2010 06; 103(6): 176–79.Google ScholarPubMed
35.Veilleux, JC, Colvin, PJ, Anderson, J, York, C, Heinz, AJ. A review of opioid dependence treatment: pharmacological and psychosocial interventions to treat opioid addiction. Clin Psychol Rev 2010 03; 30(2):155–66.CrossRefGoogle ScholarPubMed
36.National Institute for Clinical Excellence (NICE): Drug Misuse: Opioid detoxification. The NICE guideline. London: National Institute for Health and Clinical Excellence, 2008.Google Scholar
37.Marsden, J, Gossop, M, Stewart, D, Best, D, Farrell, M, Lehmann, P, Edwards, C, Strang, J. The Maudsley Addiction Profile (MAP): a brief instrument for assessing treatment outcome. Addiction 1998 12; 93(12):1857–67.CrossRefGoogle ScholarPubMed
38.Gossop, M, Marsden, J, Stewart, D, Treacy, S. Change and stability of change after treatment of drug misuse: 2-year outcomes from the National Treatment Outcome Research Study (UK). Addict Behav 2002 03-Apr; 27(2):155–66.CrossRefGoogle ScholarPubMed
39.Connors, GJ, Donovan, DM, Diclemente, CC. Substance Abuse Treatment and the stages of Change: Selecting and Planning Interventions. New York: Guilford Press; 2001.Google Scholar
40.McCrady, B. S.To have but one true friend: Implications for practice of research on alcohol use disorders and social networks. Psychology of Addictive Behaviors 2004; 18: 113121.CrossRefGoogle Scholar
41.Beck, AT, Wright, FD, Newman, CF, Liese, BS. Cognitive Therapy of Substance Abuse. New York: Guilford Press; 1993.Google Scholar
42.Cummings, C, Gordon, JR, Marlatt, GA. Relapse: Prevention and prediction. In: Miller, WR, editor. The addictive behaviours. Oxford: Pergamon Press; 1980. p 291321.Google Scholar
43.Marlatt, GA. Taxonomy of high-risk situations for alcohol relapse: evolution and development of a cognitive-behavioral model. Addiction 1996 12; 91 Suppl: S3749.Google Scholar
44.European Monitoring Centre for Drugs and Drug Addiction (EMCDDA). Selected issue 3: Co-morbidity in Annual Report 2004: The state of the drugs problem in the European Union and Norway. Luxembourg: Office for Official Publications of the European Communities, 2004.Google Scholar
45.European Monitoring Centre for Drugs and Drug Addiction (EMCDDA). Drugs in focus issue 14. Co-morbidity - drug use and mental disorders. Lisbon: European Monitoring Centre for Drugs and Drug Addiction, 2005.Google Scholar
46.Drummond, DC, Litten, RZ, Lowman, C, Hunt, WA. Craving research: future directions. Addiction 2000 08; 95 Suppl 2: S247–55.CrossRefGoogle ScholarPubMed
47.Niaura, RS. Cognitive social learning and related perspectives on drug craving. Addiction 2000; 95:S155S164.CrossRefGoogle ScholarPubMed
48.Marlatt, GA, Witkiewitz, K. Relapse prevention for alcohol and drug problems. In: Marlatt, GA, Donovan, DM, editors. Relapse prevention: Maintenance strategies in the treatment of addictive behaviors. 2nd ed. New York: Guilford Press; 2005. p 144.Google Scholar
49.Siegel, S. Drug Tolerance, Drug Addiction, and Drug Anticipation. Current Directions in Psychological Science 2005 12; 14: 296300.CrossRefGoogle Scholar
50.Kadden, R, Carroll, KM, Donovan, D, Cooney, N, Monti, P, Abrams, D, Litt, M, Hester, R. Cognitive-behavioral coping skills therapy manual: A clinical research guide for therapists treating individuals with alcohol abuse and dependence. Rockville, MD: National Institute on Alcohol Abuse and Alcoholism, 1992.Google Scholar
51.Carroll, KM. A Cognitive Behavioural Approach: Treating Cocaine Addiction. Rockville, MD: National Institute on Drug Abuse, 1998.Google Scholar
52.Hunt, GM, Azrin, NH. A community-reinforcement approach to alcoholism. Behav Res Ther 1973 02; 11(1): 91104.CrossRefGoogle ScholarPubMed
53.Gossop, M. Treating drug misuse problems: evidence of effectiveness. London: National Treatment Agency for Substance Misuse, 2006.Google Scholar
54.Groh, DR, Jason, LA, Keys, CB. Social network variables in alcoholics anonymous: a literature review. Clin Psychol Rev 2008 03; 28(3): 430–50. Review.CrossRefGoogle ScholarPubMed
55.Gossop, M, Stewart, D, Marsden, J. Attendance at Narcotics Anonymous and Alcoholics Anonymous meetings, frequency of attendance and substance use outcomes after residential treatment for drug dependence: a 5-year follow-up study. Addiction 2008 01;103(1):119–25.CrossRefGoogle ScholarPubMed
56.Ludwig, AM, Wikler, A. “Craving” and relapse to drink. Q J Stud Alcohol 1974 03; 35(1):108–30.CrossRefGoogle ScholarPubMed
57.Moos, RH. Theory-based active ingredients of effective treatments for substance use disorders. Drug Alcohol Depend 2007 05; 88(2–3): 109–21.CrossRefGoogle ScholarPubMed
58.Langendam, MW, van Haastrecht, HJ, van Ameijden, EJ. The validity of drug users' self-reports in a non-treatment setting: prevalence and predictors of incorrect reporting methadone treatment modalities. Int J Epidemiol 1999 06; 28(3):514–20.CrossRefGoogle Scholar
59.Hammerbacher, M, Lyvers, M. Factors Associated with Relapse among Clients in Australian Substance Disorder Treatment Facilities. Journal of Substance Use 2006 11:6, 387394.CrossRefGoogle Scholar
60.Gossop, M, Stewart, D, Brown, N, Marsden, J. Factors associated with abstinence, lapse or relapse to heroin use after residential treatment: protective effect of coping responses. Addiction 2002; 97: 12591267.CrossRefGoogle ScholarPubMed
61.Wanigaratne, S, Davis, P, Pryce, K, Brotchie, J. The Effectiveness of Psychological Therapies on Drug-Misusing Clients. London: NTA; 2005.Google Scholar