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Of the Right and Left Hand (1646): Sir Thomas Browne's historical survey of ‘handedness”

Published online by Cambridge University Press:  13 June 2014

Caoimhghin S Breathnach*
Affiliation:
Department of Human Anatomy and Physiology, NUI University College Dublin, Ireland

Extract

‘Handedness’ as an expression of cerebral lateralisation is valuable in analysis of hemispheric asymmetries, carrying implications for implementation (as well as interpretation) of complex cognitive functions. In recent decades it has become possible to categorise handedness in a reproducible manner and, independently, to estimate accurately the degree of language lateralisation of the brain. These advances have re-focussed attention on cerebral organisation and hemispheric asymmetries, and there is now considerable interest in the neuropsychology of left-handedness. Because of procedural and ethical constraints there are relatively few large scale studies on language dominance, whereas handedness has been studied extensively in recent decades. Language is represented in the left hemisphere in all but 1% of right-handers, and in 60% of left-handers; in 15% of right-handers speech representation was bilateral.

Precise determination of handedness or lateralisation does not appear to have been assessed in major studies of electroconvulsive therapy (ECT). Results in 29 reports, when the electrodes were placed over either the non-dominant or both hemispheres, were tabulated and briefly discussed by d'Elia and Raotma, but the criterion of lateral dominance assignment was not clearly specified; the unilateral and bilateral placements were equally efficacious in their antidepressant effect. d'Elia, who introduced unilateral therapy in 1970, accepted the assumption that the left hemisphere was ‘dominant’, but later workers were more circumspect.

Type
Historical
Copyright
Copyright © Cambridge University Press 2005

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References

1.Annett, M. Hand preference and the laterality of cerebral speech. Cortex 1975; 11: 305–28.Google Scholar
2.McManus, IC. Left hand, right hand. London: Wiedenfeld and Nicholoson, 2002.Google Scholar
3.Corballis, MC. From hand to mouth: the origin of language. Princeton: Princeton University Press, 2002.Google Scholar
4.Herron, J. Neuropsychology of left-handedness. New york: Academic Press, 1980.Google Scholar
5.Milner, B, Branch, C, Rasmussen, T. Evidence for bilateral speech representation in some non-righthanders. Trans Amer Neurol Assoc 1966; 91; 306–9.Google Scholar
6.Ojemann, GA, Whitaker, HA. The bilingual brain. Arch Neurol 1990; 35: 409–12.Google Scholar
7.d'Elia, G, Raotma, M. Is unilateral ECT less effective than bilateral ECT? Br J Psychiatry 1975; 126: 83–9. (this was not a meta-analysis)Google Scholar
8.Semmes, J. Hemispheric specialisation. A possible clue to mechanism. Neuropsychologia 1968; 6:1126.Google Scholar
9.Sackheim, HA, Prudic, J, Devanand, DPet al.Effects of stimulus intensity and electrode placement on the efficacy and cognitive effects of electroconvulsive therapy. New Engl J Med 1993; 328: 839–46.Google Scholar
10.Johnson, S. Life of Sir Thomas Browne, in Sir Thomas Browne's Works. London: George Bell and Sons. (ed. Wilkin, S.) 1901-1906, three volumes. I; ixxxxvi.Google Scholar
11.Browne, T. Pseudoxia Epidemica, (ed. Wilkin, S.) 1901-1906, three volumes. I; 391401.Google Scholar
12.Toth, N. Archaeological evidence for preferrent right-handedness in the lower and middle pleistocene and its possible implications. J Human Evolution 1985; 14: 607–14.Google Scholar
13.McManus, IC. Handedness, cerebral localisation, and the evolution of language. In: The descent of mind. Corballis, MC, Lea, SEG, eds. Oxford: Oxford University Press, 1999.Google Scholar
14.Steele, J, Mays, S. Handedness and dimensional asymmetry in the long bones of the human upper limb. Intern J Osteoarchaelogy 1995; 5: 3949.Google Scholar