Hostname: page-component-cd9895bd7-gvvz8 Total loading time: 0 Render date: 2024-12-26T18:02:56.905Z Has data issue: false hasContentIssue false
  • English
  • Français

Globus pallidus deep brain stimulators for a case of severe neuroleptic-related dystonia and dyskinesia

Published online by Cambridge University Press:  13 June 2014

Stephen McWilliams ,
Nick de Pennington ,
Tipu Z Aziz  and
Justin Brophy
Stephen McWilliams
Affiliation:
DETECT Early Intervention in Psychosis Service, 1 Marine Terrace, Dun Laoghaire, Co Dublin, Ireland
Nick de Pennington
Affiliation:
Radcliffe Infirmary, Woodstock Rd, Oxford OX2 6HE, England
Tipu Z Aziz
Affiliation:
Radcliffe Infirmary, Woodstock Rd, Oxford OX2 6HE, England
Justin Brophy*
Affiliation:
Wicklow Mental Health Services, Newcastle Hospital, Co Wicklow, Ireland
*
Correspondence Email: [email protected]
Get access Rights & Permissions [Opens in a new window]

Abstract

We report a 45 year old man with neuroleptic-induced dyskinesia for whom deep brain stimulators (DBS) were implanted in the globus pallidus internus (GPi). We describe a significant improvement in his symptoms. Lastly, we review briefly the success of deep brain stimulation to date, and discuss the clinical implications for individuals who develop movement disorders during neuroleptic use.

Keywords

ClozapineNeuroleptic-induced movement disordersDystoniaDyskinesiaDeep brain stimulatorsGlobus pallidus internus.
Type
Case reports
Information
Irish Journal of Psychological Medicine , Volume 24 , Issue 4 , December 2007 , pp. 159 - 160
Copyright
Copyright © Cambridge University Press 2007

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

1.Baldessarini, RJ. A summary of current knowledge of tardive dyskinesia. Encephale 1988; 14: 263–8.Google ScholarPubMed
2.Gafoor, R, Brophy, J. Three cases of emergent dyskinesia with clozapine. Eur Psychiatr 2003; 18: 260–261.CrossRefGoogle ScholarPubMed
3.Yianni, Jet al.Globus pallidus internus deep brain stimulation for dystonic conditions: a prospective audit. Mov Disord 2003; 18: 436–442.CrossRefGoogle ScholarPubMed
4.Bittar, RGet al.Deep brain stimulation for movement disorders and pain. J Clin Neurosci 2005; 12(4): 457–63.CrossRefGoogle ScholarPubMed
5.Starr, PAet al.Microelectrode-guided implantation of deep brain stimulators into the globus pallidus internus for dystonia: techniques, electrode locations and outcomes. Neurosurgical Focus 2004; 17(1); E4.CrossRefGoogle ScholarPubMed
6.Daimer, Pet al.Bilateral deep brain stimulation of the globus pallidus to treat tardive dyskinesia. Arch Gen Psychiatry 2007; 64(2): 170–6.CrossRefGoogle Scholar
7.Benabid, ALet al.Deep brain stimulation of the corpus luysi (subthalamic nucleus) and other targets in Parkinson's disease. Extension to new indications such as dystonia and epilepsy. J Neurol 2001; 248 (Suppl 3): III37–47.CrossRefGoogle ScholarPubMed
8.Starr, PAet al.Microelectrode-guided implantation of deep brain stimulators into the globus pallidus internus for dystonia: techniques, electrode locations and outcomes. J Neurosurgery 2006; 104(4): 488–501.CrossRefGoogle ScholarPubMed
9.Meissner, Wet al.Deep brain stimulation in late stage Parkinson's disease: a retrospective cost analysis in Germany. J Neurol 2005; 252(2): 218–23.CrossRefGoogle ScholarPubMed
10.Starr, PA. Placement of deep brain stimulators into the subthalamic nucleus or globus pallidus internus: technical approach. Stereotact Funct Neurosurg 2002; 79(3-4): 118–45.CrossRefGoogle ScholarPubMed
11.Hooper, J, Whittle, IR. Costs of thalamic deep brain stimulation for movement disorders in patients with multiple sclerosis. Br J Neurosurg 2003; 17(1): 40–5.CrossRefGoogle ScholarPubMed
12.Eltahawy, HA, Saint-Cyr, J, Poon, YY, Moro, E, Lang, AE, Lozano, AM. Pallidal deep brain stimulation in cervical dystonia: clinical outcome in four cases. Can J Neurol Sci 2004; 31(3): 293–4.CrossRefGoogle ScholarPubMed
13.Volkmann, J, Herzog, J, Kopper, F, Deuschl, G. Introduction to the programming of deep brain stimulators. Mov Disord 2002; 17(Suppl 3): S181–7.CrossRefGoogle Scholar