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Neuropathology of Psychotic Symptoms in Alzheimer's Disease

Published online by Cambridge University Press:  07 January 2005

William Bondareff
William Bondareff
Affiliation:
Department of Psychiatry, Division of Geriatric Psychiatry, University of Southern California Medical School, Los Angeles, California, U.S.A.
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Extract

An impressive body of literature has been published on the relationship between psychotic symptoms in Alzheimer's disease and pathology demonstrated primarily by neuroimaging and biochemistry studies. Jacoby and Levy in 1980 and Burns and colleagues in 1990, for example, reported less severe atrophy in delusional patients with Alzheimer's disease than in nondelusional patients with Alzheimer's disease. The author and colleagues have found that smaller ventricle-brain ratios are associated with delusions of theft in Alzheimer's disease. Zubenko (1991) and Doty (1989) have reported that delusions and hallucinations in patients with Alzheimer's disease are associated with decreased amounts of serotonin.

Type
Etiology
Information
International Psychogeriatrics , Volume 8 , Issue S3 , May 1997 , pp. 233 - 237
Copyright
© 1996 International Psychogeriatric Association

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