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Monogenic Causes of Stroke

Published online by Cambridge University Press:  10 January 2005

Martin Dichgans
Martin Dichgans
Affiliation:
Neurologische Klinik, Klinikum Grosshadern, Munich, Germany
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Abstract

Monogenic disorders account for only a minority of strokes. Yet, they have been particularly helpful in exploring basic disease mechanisms. This article summarizes some recent data on monogenic stroke while focusing on two conditions: CADASIL, as a genetic variant of ischemic small vessel disease, and familial forms of cerebral amyloid angiopathy, which share many properties with sporadic disease.

Keywords

StrokedementiamonogenicCADASILcerebral amyloid angiopathy
Type
BACKGROUND AND CURRENT CONCEPTS OF ETIOPATHOGENESIS
Information
International Psychogeriatrics , Volume 15 , Issue S1 , July 2003 , pp. 15 - 22
Copyright
© 2003 International Psychogeriatric Association

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