Hostname: page-component-cd9895bd7-dk4vv Total loading time: 0 Render date: 2024-12-25T05:27:21.482Z Has data issue: false hasContentIssue false
  • English
  • Français

Memory for emotional images differs according to the presence of depressive symptoms in individuals at risk for dementia

Published online by Cambridge University Press:  15 December 2016

Brandy L. Callahan ,
Robert Laforce Jr. ,
Michel Dugas  and
Carol Hudon Open the ORCID record for Carol Hudon [Opens in a new window]
Brandy L. Callahan*
Affiliation:
École de psychologie, Université Laval, Québec, Canada Centre de recherche du CIUSSS de la Capitale-Nationale, Québec, Canada
Robert Laforce Jr.
Affiliation:
Clinique interdisciplinaire de mémoire du CHU de Québec, Québec, Canada Département des sciences neurologiques, Faculté de médecine, Université Laval, Québec, Canada
Michel Dugas
Affiliation:
Département de gériatrie du CHU de Québec, Québec, Canada
Carol Hudon
Affiliation:
École de psychologie, Université Laval, Québec, Canada Centre de recherche du CIUSSS de la Capitale-Nationale, Québec, Canada
*
Correspondence should be addressed to: Dr. Brandy L. Callahan, Sunnybrook Research Institute, 2075 Bayview Avenue, Toronto, ON M4N 3M5, Canada. Phone: +416-480-6100 ext. 3396; Fax: +416-480-4552. Email: [email protected].
Get access

Abstract

Background:

Studies of amnestic mild cognitive impairment (aMCI) and late-life depression (LLD) have examined the similarities and differences between these syndromes, but few have investigated how the cognitive profile of comorbid aMCI and subclinical depressive symptoms (aMCI/D+) may compare to that of aMCI or LLD. Memory biases for certain types of emotional information may distinguish these groups.

Methods:

A total of 35 aMCI, 23 aMCI/D+, 13 LLD, and 17 elderly controls (CONT) rated the valence (positive, negative, or neutral) of 30 pictures from the International Affective Picture System. Mean percent positive, negative, and neutral images recalled was compared within groups immediately and 30 minutes later.

Results:

Overall memory performance was comparable in aMCI and aMCI/D+, and both recalled fewer items than CONT and LLD. Group differences emerged when valence ratings were considered: at immediate and delayed recall, positive and negative pictures were generally better-remembered than neutral pictures by CONT, aMCI, and LLD, but valence was not associated with recall in aMCI/D+. Follow-up analyses suggested that the perceived intensity of stimuli may explain the emotional enhancement effect in CONT, aMCI, and LLD.

Conclusions:

Results support previous research suggesting that the neuropsychological profile of aMCI/D+ is different from that of aMCI and LLD. Although depressed and non-depressed individuals with aMCI recall comparable quantities of information, the quality of the recalled information differs significantly. On theoretical grounds, this suggests the existence of distinct neurobiological or neurofunctional manifestations in both groups. Practically, these differences may guide the development of personalized emotion-focused encoding strategies in cognitive training programs.

Keywords

Alzheimer's diseasecognitive impairmentdementiadepressionemotionmemoryneuropsychology
Type
Research Article
Information
International Psychogeriatrics , Volume 29 , Issue 4 , April 2017 , pp. 673 - 685
Copyright
Copyright © International Psychogeriatric Association 2016 

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Alexopoulos, G. S. et al. (2013). Functional connectivity in apathy of late-life depression: a preliminary study. Journal of Affective Disorders, 149, 398–405. doi: 10.1016/j.jad.2012.11.023.Google Scholar
American Psychiatric Association (2013). Diagnostic and Statistical Manual of Mental Disorders. 5th edn. Arlington, VA: American Psychiatric Publishing.Google Scholar
Belleville, S., Sylvain-Roy, S., de Boysson, C. and Ménard, M.-C. (2008). Characterizing the memory changes in persons with mild cognitive impairment. Progress in Brain Research, 169, 365–75. doi: 10.1016/S0079-6123(07)00023-4.CrossRefGoogle ScholarPubMed
Brayne, C. et al. (2013). From molecule to clinic and community for neurodegeneration: research to bridge translational gaps. Journal of Alzheimers Disease, 33 (Suppl. 1), S385–S396.Google Scholar
Broomfield, N. M., Davies, R., MacMahon, K., Ali, F. and Cross, S. M. B. (2007). Further evidence of attention bias for negative information in late life depression. International Journal of Geriatric Psychiatry, 22, 175–180. doi: 10.1002/gps.1655.Google Scholar
Brueckner, K. and Moritz, S. (2009). Emotional valence and semantic relatedness differentially influence false recognition in mild cognitive impairment, Alzheimer's disease, and healthy elderly. Journal of the International Neuropsychological Society, 15, 268–276. doi: 10.1017/s135561770909047x.CrossRefGoogle ScholarPubMed
Brunet, J. et al. (2011). The relation between depressive symptoms and semantic memory in amnestic mild cognitive impairment and in late-life depression. Journal of the International Neuropsychological Society, 17, 865–874. doi: 10.1017/s1355617711000877.Google Scholar
Burke, J. et al. (2011). Amygdala volume in late-life depression: relationship with age of onset. The American Journal of Geriatric Psychiatry, 19, 771–776. Available at: http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=3164525&tool=pmcentrez&rendertype=abstract; last accessed 10 April 2016.Google Scholar
Callahan, B. L. et al. (2014). Semantic memory impairment for biological and man-made objects in individuals with amnestic mild cognitive impairment or late-life depression. Journal of Geriatric Psychiatry and Neurology, 28, 108–116. doi: 10.1177/0891988714554708.Google Scholar
Callahan, B. L., Simard, M., Mouiha, A., Rousseau, F., Laforce, R. Jr. and Hudon, C. (2016). Impact of Depressive Symptoms on Memory for Emotional Words in Mild Cognitive Impairment and Late-Life Depression. Journal of Alzheimer's Disease, 52, 451–462. doi: 10.3233/JAD-150585.Google Scholar
Cohen, J. (1988). Statistical Power Analysis for the Behavioral Sciences (pp. 273–406). Hillsdale, NJ: Lawrence Erlbaum Associates.Google Scholar
Consortium des Universités de Montréal et McGill (1996). Manuel De L'examen Neuropsychologique . Montréal, QC: Étude Santé et Vieillissement au Canada.Google Scholar
Crocco, E. A., Castro, K. and Loewenstein, D. A. (2010). How late-life depression affects cognition: neural mechanisms. Current Psychiatry Reports, 12, 34–38. doi: 10.1007/s11920-009-0081-2.Google Scholar
Debruyne, H. et al. (2009). Is the geriatric depression scale a reliable screening tool for depressive symptoms in elderly patients with cognitive impairment?. International Journal of Geriatric Psychiatry, 24, pp. 556–562. doi: 10.1002/gps.2154.CrossRefGoogle Scholar
Delis, D. C., Kaplan, E. and Kramer, J. H. (2001). Delis Kaplan Executive Function System: Technical Manual. San Antonio, TX: Psychological Corporation.Google Scholar
Dierckx, E., Engelborghs, S., De Raedt, R., De Deyn, P. P. and Ponjaert-Kristoffersen, I. (2007). Differentiation between mild cognitive impairment, Alzheimer's disease and depression by means of cued recall. Psychological Medicine, 37, 747–755. doi: 10.1017/s003329170600955x.Google Scholar
Faul, F., Erdfelder, E., Lang, A.-G. and Buchner, A. (2007). G*Power 3: a flexible statistical power analysis program for the social, behavioral, and biomedical sciences. Behavior research methods, 39, 175–191. Available at: http://www.ncbi.nlm.nih.gov/pubmed/17695343; last accessed 21 October 2016).Google Scholar
Foland-Ross, L. C. and Gotlib, I. H. (2012). Cognitive and neural aspects of information processing in major depressive disorder: an integrative perspective. Frontiers in Psychology, 3, 489. doi: 10.3389/fpsyg.2012.00489.CrossRefGoogle ScholarPubMed
Galasko, D. et al. (1997). An inventory to assess activities of daily living for clinical trials in Alzheimer's disease. The Alzheimer's Disease Cooperative Study. Alzheimer Disease and Associated Disorders, 11 (Suppl. 2), S33–S39. Available at: http://www.ncbi.nlm.nih.gov/pubmed/9236950; last accessed 16 March 2016.Google Scholar
Gorenc-Mahmutaj, L., Degen, C., Wetzel, P., Urbanowitsch, N., Funke, J. and Schröder, J. (2015). The positivity effect on the intensity of experienced emotion and memory performance in mild cognitive impairment and dementia. Dementia and Geriatric Cognitive Disorders Extra, 5, 233–243. Available at: http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=4483493&tool=pmcentrez&rendertype=abstract; last accessed 21 December 2015.CrossRefGoogle ScholarPubMed
Gotlib, I. H. and Joormann, J. (2010). Cognition and depression: current status and future directions. Annual Review of Clinical Psychology, 6, 285–312. doi: 10.1146/annurev.clinpsy.121208.131305.CrossRefGoogle ScholarPubMed
Grober, E., Buschke, H., Crystal, H., Bang, S. and Dresner, R. (1988). Screening for dementia by memory testing. Neurology, 38, 900–903.Google Scholar
Hachinski, V. C. et al. (1975). Cerebral blood flow in dementia. Archieves of Neurology, 32, 632–637.Google Scholar
Herrmann, L. L., Goodwin, G. M. and Ebmeier, K. P. (2007). The cognitive neuropsychology of depression in the elderly. Psychological Medicine, 37, 1693–1702. doi: 10.1017/s0033291707001134.Google Scholar
Howard, D. and Patterson, K. (1992). The Pyramids and Palm Trees Test: A Test of Semantic Access from Words and Pictures. Bury St. Edmunds: Thames Valley Test Company.Google Scholar
Hudon, C., Belleville, S. and Gauthier, S. (2008). The association between depressive and cognitive symptoms in amnestic mild cognitive impairment. International Psychogeriatrics, 20, 710–723. doi: 10.1017/s1041610208007114.Google Scholar
Ito, T. A., Cacioppo, J. T. and Lang, P. J. (1998). Eliciting affect using the international affective picture system: trajectories through evaluative space. Personality and Social Psychology Bulletin, 24, 855–879. doi: 10.1177/0146167298248006.Google Scholar
Johnson, L. A. et al. (2013). Cognitive differences among depressed and non-depressed MCI participants: a project FRONTIER study. International Journal of Geriatric Psychiatry, 28, 377–82. doi: 10.1002/gps.3835.Google Scholar
Jurica, P., Leittan, C. and Mattis, S. (2001). DRS-2: Dementia Rating Scale-2 Professional Manual. Lutz, FL: Psychological Assessment Resources.Google Scholar
Kensinger, E. A., Brierley, B., Medford, N., Growdon, J. H. and Corkin, S. (2002). Effects of normal aging and Alzheimer's disease on emotional memory. Emotion, 2, 118–134. doi: 10.1037//1528-3542.2.2.118.Google Scholar
Kensinger, E. A. and Leclerc, C. M. (2009). Age-related changes in the neural mechanisms supporting emotion processing and emotional memory. European Journal of Cognitive Psychology, 21, 192–215.Google Scholar
Klein-Koerkamp, Y., Baciu, M. and Hot, P. (2012). Preserved and impaired emotional memory in Alzheimer's disease. Frontiers in Psychology, 3, 1–12. doi: 10.3389/fpsyg.2012.00331.Google Scholar
Lang, P. J., Bradley, M. M. and Cuthbert, B. N. (2005). International Affective Picture System (IAPS): Affective Ratings of Pictures and Instruction Manual. Technical Report A-6. Gainesville, FL: University of Florida.Google Scholar
Lee, G. et al. (2012). Depressive symptoms in mild cognitive impairment predict greater atrophy in Alzheimer's disease-related regions. Biological Psychiatry, 71, 814–821. doi: 10.1016/j.biopsych.2011.12.024.Google Scholar
Libkuman, T. M., Otani, H., Kern, R., Viger, S. G. and Novak, N. (2007). Multidimensional normative ratings for the international affective picture system. Behavior Research Methods, 39, 326–334. doi: 10.3758/BF03193164.Google Scholar
Lopez, O. L., Becker, J. T. and Sweet, R. A. (2005). Non-cognitive symptoms in mild cognitive impairment subjects. Neurocase, 11, 65–71. doi: 10.1080/13554790490896893.Google Scholar
Mack, W. J., Freed, D. M., Williams, B. W. and Henderson, V. W. (1992). Boston naming test – shortened versions for use in Alzheimer's disease. Journals of Gerontology, 1420, P154–P158.Google Scholar
Mah, L. and Pollock, B. G. (2010). Emotional processing deficits in late-life depression. American Journal of Geriatric Psychiatry, 18, 652–656. doi: 10.1097/JGP.0b013e3181d6b762.Google Scholar
Mah, L., Wen, M. C., Grady, C. L., Anderson, N. D. and Pollock, B. G. (2012). Half empty or half full? Emotional biases differentiate late-life depression and amnestic mild cognitive impairment. Society for Neuroscience Abstract Viewer and Itinerary Planner, 42. Available at: http://www.abstractsonline.com/plan/ViewAbstract.aspx?cKey=3d196008-195d-44bb-bdf7-bd2bb8e853a0&mID=2964&mKey=%7b70007181-01C9-4DE9-A0A2-EEBFA14CD9F1%7d&sKey=49b8eaac-8fac-44ee-9e4e-5ddfc672996f; last accessed 28 November 2016.Google Scholar
Marreneca, S., Martins, J., Mendonça, A. and Guerreiro, M. (2006). Emotional memory in mild cognitive impairment. Alzheimer's & Dementia, 2, S295–S296. doi: 10.1016/j.jalz.2006.05.1043.Google Scholar
Mather, M. and Carstensen, L. L. (2005). Aging and motivated cognition: the positivity effect in attention and memory. Trends in Cognitive Sciences, 9, 496–502. doi: 10.1016/j.tics.2005.08.005.CrossRefGoogle ScholarPubMed
Matt, G. E., Vazquez, C. and Campbell, W. K. (1992). Mood-congruent recall of affectively toned stimuli – a meta-analytic review. Clinical Psychology Review, 12, 227–255. doi: 10.1016/0272-7358(92)90116-p.Google Scholar
Mistridis, P., Taylor, K. I., Kissler, J. M., Monsch, A. U., Kressig, R. W. and Kivisaari, S. L. (2013). Distinct neural systems underlying reduced emotional enhancement for positive and negative stimuli in early Alzheimer's disease. Frontiers in Human Neuroscience, 7, 939. doi: 10.3389/fnhum.2013.00939.Google Scholar
Morin, J.-F., Mouiha, A., Pietrantonio, S., Duchesne, S. and Hudon, C. (2012). Structural neuroimaging of concomitant depressive symptoms in amnestic mild cognitive impairment: a pilot study. Dementia and Geriatric Cognitive Disorders Extra, 2, 573–88. doi: 10.1159/000345234.Google Scholar
Moritz, S., Voigt, K., Arzola, G. M. and Otte, C. (2008). When the half-full glass is appraised as half empty and memorised as completely empty: mood-congruent true and false recognition in depression is modulated by salience. Memory, 16, 810–820. doi: 10.1080/09658210802282708.Google Scholar
Nasreddine, Z. S. et al. (2005). The montreal cognitive assessment, MoCA: a brief screening tool for mild cognitive impairment. Journal of the American Geriatrics Society, 53, 695–699. doi: 10.1111/j.1532-5415.2005.53221.x.CrossRefGoogle Scholar
Nieuwenhuis-Mark, R. E., Schalk, K. and de Graaf, N. (2009). Free recall and learning of emotional word lists in very elderly people with and without dementia. American Journal of Alzheimers Disease and Other Dementias, 24, 155–162. doi: 10.1177/1533317508330561.Google Scholar
Osborne, J. (2002). Notes on the use of data transformations. Practical Assessment, Research & Evaluation, 8. Available at: http://pareonline.net/getvn.asp?v=8&n=6; last accessed 18 March 2016.Google Scholar
Parra, M. et al. (2013). Medial temporal lobe function during emotional memory in early Alzheimer's disease, mild cognitive impairment and healthy ageing: an fMRI study. BMC Psychiatry, 13, 76. doi: 10.1186/1471-244X-13-76.CrossRefGoogle ScholarPubMed
Pellegrino, L. D., Peters, M. E., Lyketsos, C. G. and Marano, C. M. (2013). Depression in cognitive impairment. Current Psychiatry Reports, 15, 384. doi: 10.1007/s11920-013-0384-1.Google Scholar
Petersen, R. C. (2004). Mild cognitive impairment as a diagnostic entity. Journal of Internal Medicine, 256, 183–194.CrossRefGoogle ScholarPubMed
Rey, A. (1941). Psychological examination in cases of traumatic encephalopathy. Archives De Psychologie, 28, 286–340.Google Scholar
Richard, E. et al. (2013). Late-life depression, mild cognitive impairment, and dementia. JAMA Neurology, 70, 383–389. doi: 10.1001/jamaneurol.2013.603.Google Scholar
Riddoch, J. M. and Humphreys, J. D. (1993). Birmingham Object Recognition Battery (BORB). Psychology Press.Google Scholar
Schultz, R. R., De Castro, C. C. and Bertolucci, P. H. F. (2009). Memory with emotional content, brain amygdala and Alzheimer's disease. Acta Neurologica Scandinavica, 120, 101–110. doi: 10.1111/j.1600-0404.2008.01132.x.Google Scholar
Son, G. R., Therrien, B. and Whall, A. (2002). Implicit memory and familiarity among elders with dementia. Journal of Nursing Scholarship, 34, 263–267. doi: 10.1111/j.1547-5069.2002.00263.x.Google Scholar
Steffens, D. C. et al. (2006). Perspectives on depression, mild cognitive impairment, and cognitive decline. Archives of General Psychiatry, 63, 130–138.Google Scholar
Thomas Antérion, C., Ribas, C., Honoré-Masson, S., Berne, G., Ruel, J. H. and Laurent, B. (2003). Le questionnaire de plainte cognitive (QPC): un outil de recherche de plainte suspecte d’évoquer une maladie d'Alzheimer?. L'Année Gérontologique, 17, 56–65.Google Scholar
Troyer, A. K., Murphy, K. J., Anderson, N. D., Moscovitch, M. and Craik, F. I. M. (2008). Changing everyday memory behaviour in amnestic mild cognitive impairment: a randomised controlled trial. Neuropsychological Rehabilitation, 18, 65–88. doi: 10.1080/09602010701409684.Google Scholar
Van der Linden, M. (2004). L’Évaluation des Troubles de la Mémoire: Présentation de Quatre Tests de Mémoire Épisodique (avec leur Étalonnage). Marseille, France: Solal Éditeurs.Google Scholar
Wang, P. et al. (2013). Is emotional memory enhancement preserved in amnestic mild cognitive impairment? Evidence from separating recollection and familiarity. Neuropsychology. doi: 10.1037/a0033973.Google Scholar
Waring, J. D., Seiger, A. N., Solomon, P. R., Budson, A. E. and Kensinger, E. A. (2014). Memory for the 2008 presidential election in healthy ageing and mild cognitive impairment. Cognition & Emotion, 28, 1407–1421. doi: 10.1080/02699931.2014.886558.Google Scholar
Werheid, K., Gruno, M., Kathmann, N., Fischer, H., Almkvist, O. and Winblad, B. (2010). Biased recognition of positive faces in aging and amnestic mild cognitive impairment. Psychology and Aging, 25, 1–15. doi: 10.1037/a0018358.Google Scholar
Yesavage, J. A. et al. (1983). Development and validation of a geriatric depression screening scale – a preliminary report. Journal of Psychiatric Research, 17, 37–49.CrossRefGoogle Scholar
Supplementary material: File

Callahan supplementary material

Supplementary Table

Download Callahan supplementary material(File)
File 20.8 KB