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Manic episode precedes development of early dementia: a case report

Published online by Cambridge University Press:  28 May 2010

Li Yu Hu  and
Yuan-Hwa Chou
Li Yu Hu
Affiliation:
Department of Psychiatry, Taipei Veterans General Hospital and National Yang Ming University, Taipei, Taiwan
Yuan-Hwa Chou*
Affiliation:
Department of Psychiatry, Taipei Veterans General Hospital and National Yang Ming University, Taipei, Taiwan Institute of Neuroscience, National Yang Ming University, Taipei, Taiwan
*
Correspondence should be addressed to: Yuan-Hwa Chou MD, PhD, Department of Psychiatry, Taipei Veterans General Hospital, No. 201, Sec. 2, Shih-Pai Rd, 112, Peitou, Taipei, Taiwan. Phone: +886-2-2871-1290; Fax: +886-2-2876-8403. Email: [email protected].
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Abstract

We report a case of a 63-year-old man who experienced his first manic episode, and then, one year later, experienced a second episode which was associated with a significant loss of brain parenchyma. Two computed tomography (CT) brain scans were performed at each manic episode to observe brain structure. Significant loss of brain parenchyma was shown using CT scans. A Mini-mental State Examination (MMSE) score of 29 was observed after the first manic episode and a score of 23 was obtained after the second manic episode. This case report supports the idea that an increased risk of developing dementia exists in patients with major affective disorders.

Keywords

manic episodedementia
Type
Case Report
Information
International Psychogeriatrics , Volume 22 , Issue 5 , August 2010 , pp. 834 - 836
Copyright
Copyright © International Psychogeriatric Association 2010

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