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Functional Brain Imaging as a Surrogate Marker in Vascular Cognitive Impairment

Published online by Cambridge University Press:  10 January 2005

Etsuro Mori
Etsuro Mori
Affiliation:
Department of Clinical Neurosciences, Hyogo Institute for Aging Brain and Cognitive Disorders, Himeji, Japan
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Abstract

Functional brain imaging represents cerebrovascular status, neuronal status, and neuronetwork status, and plays an increasingly important role in the evaluation of vascular cognitive impairment or vascular dementia. In this article, the roles of functional brain imaging are discussed in evaluation of subcortical lesions disrupting cortico-subcortical circuits and in the study of white-matter changes in dementia. Also mentioned is an ongoing clinical trial of extracranial-intracranial artery bypass surgery for hemispheric hemodynamic misery perfusion where single-photon emission tomography is used as a surrogate measure.

Keywords

Functional brain imagingpositron emission tomographysingle-photon emission tomographyvascular dementiacognitive impairment
Type
TRIL DESIGNS: SLOW PROGRESSION
Information
International Psychogeriatrics , Volume 15 , Issue S1 , July 2003 , pp. 267 - 272
Copyright
© 2003 International Psychogeriatric Association

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