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Cognitive performance norms from the Korean genome and epidemiology study (KoGES)

Published online by Cambridge University Press:  13 July 2017

Hyun Kim ,
Rhoda Au ,
Robert J. Thomas ,
Chang-Ho Yun ,
Seung Ku Lee ,
Changsu Han  and
Chol Shin
Hyun Kim
Affiliation:
Department of Psychological and Brain Sciences, Boston University, Boston, USA Departments of Anatomy & Neurobiology, Neurology and Framingham Heart Study, Boston University School of Medicine, Boston, Massachusetts, USA Department of Epidemiology, Boston University School of Public Health, USA Institute of Human Genomic Study, Korea University Ansan Hospital, South Korea
Rhoda Au
Affiliation:
Departments of Anatomy & Neurobiology, Neurology and Framingham Heart Study, Boston University School of Medicine, Boston, Massachusetts, USA Department of Epidemiology, Boston University School of Public Health, USA
Robert J. Thomas
Affiliation:
Division of Pulmonary, Critical Care, and Sleep Medicine, Beth Israel Deaconess Medical Center, USA
Chang-Ho Yun
Affiliation:
Department of Neurology, Seoul National University Bundang Hospital, South Korea
Seung Ku Lee
Affiliation:
Institute of Human Genomic Study, Korea University Ansan Hospital, South Korea
Changsu Han
Affiliation:
Department of Psychiatry, Korea University College of Medicine, South Korea
Chol Shin*
Affiliation:
Institute of Human Genomic Study, Korea University Ansan Hospital, South Korea Department of Respiratory Internal Medicine, Korea University Ansan Hospital, South Korea
*
Correspondence should be addressed to: Chol Shin, MD, PhD, FCCP, Korea University Ansan Hospital, #516, Gojan1-dong, Danwon-gu, Ansan, Kyeonggi-do, South Korea. Phone: +82-31-412-5603; Fax: +82-31-412-5604. Email: [email protected].
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Abstract

Background:

While normative data on neuropsychological performance provide baseline metrics for the assessment and diagnosis of mild cognitive impairment and dementia, a lack of comparative normative data in non-Caucasian populations makes it difficult to conduct similar evaluations and studies in individuals from diverse backgrounds. The current paper aims to provide normative data on a range of cognitive measures in a Korean general population sample and investigate various demographic and health variables associated with cognitive performance in this representative population.

Method(s):

The study population was 1,528 stroke and dementia-free individuals who participated in the Korean Genome and Epidemiology study (KoGES) (mean age 60.43 ± 7.30, 52.42% female). All participants underwent a comprehensive neuropsychological test battery that included verbal and visual memory, language, attention, and executive function measures. A health examination and a questionnaire-based interview were also administered.

Results:

The majority of cognitive test results were associated with age, education, and gender. In general, higher education and younger age was associated with better cognitive performance. Explained variance increased modestly in models that included measures of general health and depressive symptoms.

Conclusion:

Normative data of cognitive performance in a community based Korean population are presented. These norms provide reference values in a non-Caucasian middle to older aged sample.

Keywords

neuropsychological testingepidemiology
Type
Research Article
Information
International Psychogeriatrics , Volume 29 , Issue 11 , November 2017 , pp. 1909 - 1924
Copyright
Copyright © International Psychogeriatric Association 2017 

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Footnotes

The current work was performed at the Institute of Human Genomic Study, Korea University Ansan Hospital.

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