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Validation of the General Practitioner Assessment of Cognition – Chinese version (GPCOG-C) in China

Published online by Cambridge University Press:  09 July 2013

Xia Li
Affiliation:
Department of Psychogeriatrics, Shanghai Mental Health Center, Shanghai Jiaotong University School of Medicine, and Alzheimer's Disease and Related Disorders Center, Shanghai Jiaotong University, Shanghai, China
Shifu Xiao*
Affiliation:
Department of Psychogeriatrics, Shanghai Mental Health Center, Shanghai Jiaotong University School of Medicine, and Alzheimer's Disease and Related Disorders Center, Shanghai Jiaotong University, Shanghai, China
Yuan Fang
Affiliation:
Department of Psychogeriatrics, Shanghai Mental Health Center, Shanghai Jiaotong University School of Medicine, and Alzheimer's Disease and Related Disorders Center, Shanghai Jiaotong University, Shanghai, China
Minjie Zhu
Affiliation:
Department of Psychogeriatrics, Shanghai Mental Health Center, Shanghai Jiaotong University School of Medicine, and Alzheimer's Disease and Related Disorders Center, Shanghai Jiaotong University, Shanghai, China
Tao Wang
Affiliation:
Department of Psychogeriatrics, Shanghai Mental Health Center, Shanghai Jiaotong University School of Medicine, and Alzheimer's Disease and Related Disorders Center, Shanghai Jiaotong University, Shanghai, China
Katrin Seeher
Affiliation:
Dementia Collaborative Research Centre, University of New South Wales, Sydney, Australia Academic Department for Old Age Psychiatry, Prince of Wales Hospital, Sydney, Australia Centre for Healthy Brain Ageing, University of New South Wales, Sydney, Australia
Henry Brodaty
Affiliation:
Dementia Collaborative Research Centre, University of New South Wales, Sydney, Australia Academic Department for Old Age Psychiatry, Prince of Wales Hospital, Sydney, Australia Centre for Healthy Brain Ageing, University of New South Wales, Sydney, Australia
*
Correspondence should be addressed to: Prof. Shifu Xiao, Department of Psychogeriatrics, Shanghai Mental Health Center, Shanghai Jiaotong University School of Medicine, and Alzheimer's Disease and Related Disorders Center, Shanghai Jiaotong University, The South Wanping Road 600, Shanghai, China. Phone: +86-21-34289888; Fax: +86-21-54259931. Email: [email protected].

Abstract

Background:

To assess the reliability, validity, and diagnostic utility of the Chinese version of General Practitioner Assessment of Cognition (GPCOG-C). The GPCOG, which is specifically designed for use in primary care to screen for cognitive impairment, consists of a patient section testing cognition, and an informant section asking about decline in cognitive and functional abilities.

Methods:

The English version of GPCOG was translated, back-translated, and subsequently revised to determine the final GPCOG-C. Our sample comprised 253 community-dwelling volunteers with memory concerns aged 50 years and over and 103 outpatients of a psychogeriatric clinic with memory complaints. Participants were assessed by one of the four general practitioners or six psychogeriatricians. The Mini-Mental State Examination (MMSE), the Hasegawa's Dementia Scale (HDS), and the GPCOG-C were compared against the DSM-IV-defined dementia diagnosis.

Results:

The internal consistency (Cronbach's α) was 0.68 for the GPCOG patient section. The test–retest was 0.98 for the GPCOG-C total. The sequential administration of both components of GPCOG-C had a sensitivity of 97% and a specificity of 89%, with a positive predictive value of 72% and a negative predictive value of 99%. Both the GPCOG-C total and sequential two-stage scoring methods performed at least well as the MMSE and HDS in detecting dementia. The administration time for the two-stage approach was 4.3 ± 2.4 min.

Conclusions:

The GPCOG-C is a valid, time efficient instrument for dementia screening in China.

Type
Research Article
Copyright
Copyright © International Psychogeriatric Association 2013 

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