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Alzheimer's Disease: Relationship of Cognition and Behavior to Neurochemistry

Published online by Cambridge University Press:  07 January 2005

Peter J. Whitehouse
Affiliation:
Alzheimer Center University Hospitals of Cleveland and Division of Behavioral Neurology, Case Western Reserve University, Cleveland, Ohio, U.S.A.

Abstract

Alzheimer's disease is characterized by loss of cells and synapses in specific neural systems. The development of more effective therapies will depend on understanding the relationships between this pathology and the cognitive and behavioral impairments. In this review, focusing primarily on work in our laboratory, we will examine both classic and neuropeptide neurotransmitter systems and will discuss conceptual and methodological problems in relating clinical and biological measures.

Type
Research Article
Copyright
© 1992 Springer Publishing Company

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