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Electrolyte Balance

Published online by Cambridge University Press:  10 March 2009

Anita Aperia  and
Peter Herin
Anita Aperia
Affiliation:
St. Göran's Children's HospitalStockholm
Peter Herin
Affiliation:
St. Göran's Children's HospitalStockholm
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Extract

The kidney is structurally and biochemically immature at birth. As a consequence, renal function is low (3;10;ll;18). Glomerular filtration rate (related to body surface area or to body weight) is approximately 25% of that in adults. The capacity of several different tubular transport systems is lower in the infant than in the adult (2;5;13;21;28). A low transporting capacity of the neonatal kidney will sometimes result in undesired losses of electrolytes, amino acids, and peptides. The capacity to concentrate urine is low (7;29), and disturbances of serum tonicity, therefore, are common. The low concentrating capacity can be attributed to renal immaturity. The capacity of the newborn fullterm as well as preterm infant to release antidiuretic hormone is normal 7;31).

Type
Neonatal Disorders of Water and Heat Balance
Information
International Journal of Technology Assessment in Health Care , Volume 7 , Supplement S1 , January 1991 , pp. 90 - 93
Copyright
Copyright © Cambridge University Press 1991

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References

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