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Bronchopulmonary Dysplasia: Pharmacologic Treatments and Prediction of Outcome

Published online by Cambridge University Press:  10 March 2009

William E. Truog
William E. Truog
Affiliation:
University of Washington School of Medicine
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Extract

Bronchopulmonary dysplasia (BPD) is a progressive disorder of the lungs of newborn infants initially involving distal airways, but followed in weeks by the development of abnormalities in all parts of the lung architecture. BPD develops primarily but not exclusively in premature infants. The incidence in the general population has never been assessed accurately in a prospective manner. One retrospectively calculated incidence figure is 1.2 infants per 1,000 total live births per year in the United States (17). With approximately 4 million births annually in North America, there are about 5,000 babies each year who develop BPD. The additional weeks, months, and, in some cases, years of hospitalization, the frequent rehospitalizations, and the mortality of 20–50% beyond 1 month of age (17) underscore the disproportionate financial and emotional toll of BPD not only on patients and families but caregivers as well. The glacial rates of improvement in the illness, the frequent setbacks, and the profound disruption to family life all support the contention that BPD is a major public health problem.

Type
Neonatal Disorders of Respiration
Information
International Journal of Technology Assessment in Health Care , Volume 7 , Supplement S1 , January 1991 , pp. 61 - 65
Copyright
Copyright © Cambridge University Press 1991

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References

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