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Validity of utilities of patients with esophageal cancer

Published online by Cambridge University Press:  02 March 2005

Peep F. M. Stalmeier ,
Angela G. E. M. de Boer ,
Mirjam A. G. Sprangers ,
Hanneke C. J. M. de Haes  and
Jan J. B. van Lanschot
Peep F. M. Stalmeier
Affiliation:
University Medical Centre Nijmegen
Angela G. E. M. de Boer
Affiliation:
Academic Medical Centre/University of Amsterdam
Mirjam A. G. Sprangers
Affiliation:
Academic Medical Centre/University of Amsterdam
Hanneke C. J. M. de Haes
Affiliation:
Academic Medical Centre/University of Amsterdam
Jan J. B. van Lanschot
Affiliation:
Academic Medical Centre/University of Amsterdam
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Abstract

Objectives: The convergent validity between utility assessment methods was assessed.

Methods: Investigated were patients with esophageal cancer treated surgically with curative intent. Patients were interviewed in a period from 3 to 12 months after surgical resection. Patients evaluated their actual health and seven other states. Visual analogue scale (VAS) and standard gamble (SG) utilities were obtained for the health states in an interview. Patients also indicated whether or not they preferred death to living in a health state (worse than dead [WTD] preferences).

Results: Fifty patients completed the interview. Convergent validity was excellent at the aggregate and individual level. However, the relation between VAS and SG differed strongly across individuals. On a scale from 0 (dead) to 100 (perfect health), SG scores were lower for patients with WTD preferences (mean difference d=35; p=.002); however, VAS scores did not vary by WTD preferences.

Conclusions: In general, there is good agreement between VAS and SG measures, although patients disagree about how the VAS and SG are related. The standard gamble varied by WTD preferences, however, the VAS did not.

Keywords

Utility assessmentEsophageal cancer
Type
RESEARCH REPORTS
Information
International Journal of Technology Assessment in Health Care , Volume 21 , Issue 1 , January 2005 , pp. 113 - 118
Copyright
© 2005 Cambridge University Press

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