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Protein a Immunoadsorption Column Versus Splenectomy in the Treatment of Steroid-resistant Immune Thrombocytopenic Purpura: A Cost-Effectiveness Analysis

Published online by Cambridge University Press:  10 March 2009

Kimberly Kunz ,
Miriam Kuppermann ,
Thomas Bowe ,
Amy Williamson  and
Peter Mazonson
Kimberly Kunz
Affiliation:
Technology Assessment Group
Miriam Kuppermann
Affiliation:
Technology Assessment Group
Thomas Bowe
Affiliation:
Technology Assessment Group
Amy Williamson
Affiliation:
Technology Assessment Group
Peter Mazonson
Affiliation:
Technology Assessment Group
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Abstract

The protein A immunoadsorption column is a new treatment for immune thrombocytopenic purpura (ITP). We used a decision-analytic approach with a Markov process to model the cost effectiveness of this treatment compared with splenectomy for steroid-resistant ITP patients. Data informing the model were obtained from published literature, a panel of physicians, and public databases. We found initial treatment with the protein A immunoadsorption column to be less expensive and more effective than initial treatment with splenectomy.

Type
General Essays
Information
International Journal of Technology Assessment in Health Care , Volume 12 , Issue 3 , Summer 1996 , pp. 436 - 449
Copyright
Copyright © Cambridge University Press 1996

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