Hostname: page-component-cd9895bd7-gbm5v Total loading time: 0 Render date: 2024-12-19T12:07:51.119Z Has data issue: false hasContentIssue false

Fecal Occult Blood Tests: A Cost-effectiveness Analysis

Published online by Cambridge University Press:  10 March 2009

Dorte Gyrd-Hansen
Affiliation:
Odense University

Abstract

A range of fecal occult blood tests are presently on the market and could potentially be used in population screening programs for the detection of colorectal neoplasms. This paper estimates the relative cost-effectiveness of alternative tests and concludes that the unhydrated Hemoccult II is the most cost-effective. However, the incremental costs per life-year of the HemeSelect test and the rehydrated Hemoccult II test are in line with incremental costs observed in breast cancer and cervical cancer programs.

Type
General Essays
Copyright
Copyright © Cambridge University Press 1998

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

REFERENCES

1.Ahlquist, D. A., Wieand, H. S., Moertel, C. G., et al. Accuracy of fecal occult blood-screening for colorectal neoplasia. Journal of American Medical Association, 1993, 269, 1262–67.CrossRefGoogle ScholarPubMed
2.Allison, J. E., Tekawa, I. S., Ransom, L. J., & Adrain, A. L.A comparison of fecaloccult blood tests for colorectal-cancer screening. New England Journal of Medicine, 1996, 334, 155–59.CrossRefGoogle Scholar
3.Atkin, W. S., Morson, B. C., & Cuzick, J.Long-term risk of colorectal cancer after excision of rectosigmoid adenomas. New England Journal of Medicine, 1992, 326, 658–62.CrossRefGoogle ScholarPubMed
4.Bang, K. M., Tillett, S., Hoar, S. K., et al. Sensitivity of fecal hemoccult testing and flexible sigmoidoscopy for colorectal cancer screening. Journal of Occupational Medicine, 1986, 28, 709–13.CrossRefGoogle ScholarPubMed
5.Day, N. E. & Walter, S. D.Simplified models for screening for chronic disease: Estimation procedures for mass screening programmes. Biometrics, 1984, 40, 114.CrossRefGoogle ScholarPubMed
6.De Koning, H. J., Van Ineveld, B. M., Oortmarssen, G. J., et al. Breast cancer screening and cost-effectiveness: Policy alternatives, quality of life considerations and the possible impact of uncertain factors. International Journal of Cancer, 1991, 49, 531–37.CrossRefGoogle ScholarPubMed
7.Demers, R. Y., Stawick, L. E. & Demers, P.Relative sensitivity of the fecal occult blood test and flexible sigmoidoscopy in detecting polyps. Preventive Medicine, 1985, 14, 5562.CrossRefGoogle ScholarPubMed
8.Grossman, S., Milos, M. L., Tekawa, I. S. & Jewell, N. P.Colonoscopic screening for persons with suspected risk factors for colon cancer. II. Past history of colorectal neoplasms. Gastroenterology, 1989, 96, 299306.CrossRefGoogle ScholarPubMed
9.Gyrd-Hansen, D.Breast cancer screening: A sensitivity analysis. CHS Working Paper 1997:5. Odense: Odense University, 1997.Google Scholar
10.Gyrd-Hansen, D., Hølund, B., & Andersen, P.A cost-effectiveness analysis of cervical cancer screening: Health policy implications. Health Policy, 1995, 34, 3551.CrossRefGoogle ScholarPubMed
11.Gyrd-Hansen, D., Søegaard, J., & Kronborg, O.Analysis of screening data: Colorectal cancer. International Journal of Epidemiology, 1997, 26, 1172–81.CrossRefGoogle ScholarPubMed
12.Gyrd-Hansen, D., Søegaard, J. & Kronborg, O. Colorectal cancer screening: Efficiency and effectiveness. Health Economics, in press.Google Scholar
13.Gyrd-Hansen, D., Søgaard, J., & Kronborg, O.Analysing colorectal screening data using a mathematical model. CHS Working Paper 1996:9. Odense: Odense University, 1996.Google Scholar
14.Kewenter, J., Brevinge, H., Engarås, T., et al. Result of screening, rescreening and follow-up in a prospective randomized study for detection of colorectal cancer by fecal occult blood testing. Scandinavian Journal of Gastroenterology, 1994, 29, 468–73.CrossRefGoogle Scholar
15.Koopmanschap, M. A., Lubbe, K. H. T, Van Oortmarssen, G. J., et al. Economic aspects of cervical cancer screening. Social Science and Medicine, 1990, 30, 1081–87.CrossRefGoogle ScholarPubMed
16.Kronborg, O., Fenger, C., Olsen, J., Jøgensen, O. D., & Søndergaard, O.A randomised study of screening for colorectal cancer with fecal occult blood test at Funen in Denmark. Lancet, 1996, 348, 1467–71.CrossRefGoogle Scholar
17.Letsou, G., Ballantyne, G. H., Zdon, M. J., et al. Screening for colorectal neoplasms: A comparison of the fecal occult blood test and endoscopic examination. Diseases of the Colon and Rectum, 1987, 30, 839–43.CrossRefGoogle ScholarPubMed
18.Mandel, J. S., Bond, J. H., Church, T. R., et al. Reducing mortality from colorectal cancer by screening for fecal occult blood. New England Journal of Medicine, 1993, 328, 1365–71.CrossRefGoogle ScholarPubMed
19.Rozen, P., Ron, E., Fireman, Z., et al. The relative value of fecal occult blood tests and flexible sigmoidoscopy in screening for large bowel neoplasia. Cancer, 1987, 60, 2553–58.3.0.CO;2-S>CrossRefGoogle ScholarPubMed
20.Spencer, R. J., Melton, L. J. III, Ready, R. L., & Ilstrup, D.M.Treatment of small colorectal polyps: A population based study of the risk of subsequent carcinoma. Mayo Clinic Proceedings, 1984, 59, 305–10.CrossRefGoogle ScholarPubMed
21.St. John, D. J. B., Young, G. P., Alexeyeff, M. A., et al. Evaluation of new occult blood tests for detection of colorectal neoplasia. Gastroenterology, 1993, 104, 1661–68.CrossRefGoogle ScholarPubMed
22.Thomas, W. M., Hardcastle, J. D., Jackson, J., & Pye, G.Chemical and immunological testing for faecal occult blood: A comparison of two tests in symptomatic patients. British Journal of Cancer, 1992, 65, 618620.CrossRefGoogle ScholarPubMed
23.Wagner, J. L., Tunis, S., Brown, M., et al. Cost-effectiveness of colorectal cancer screening in average-risk adults. In Young, G. P., Rozen, P., & Levin, B. (eds.), Prevention and early detection of colorectal cancer. London: W.B. Saunders Company Ltd., 1996.Google Scholar
24.Walker, A. R., Whynes, D. K., Chamberlain, J. O., & Hardcastle, J. D.The hospital costs of diagnostic procedures for colorectal cancer. Journal of Clinical Epidemiology, 1991, 44, 907–14.CrossRefGoogle ScholarPubMed