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Published online by Cambridge University Press: 12 April 2016
For three quarters of a century pulsating variable stars have lain at the foundation of the extragalactic distance scale. The construction of larger telescopes, advances in detector technology, hard work by observers, and our understanding of stellar structure have all contributed to the expansion of the realm of the Cepheids to the distance of M101. Now, with the advent of Hubble Space Telescope (HST), we can look forward to the detection of Cepheids in the Virgo cluster and the removal of much of the remaining uncertainty in the Hubble constant.