Hostname: page-component-586b7cd67f-rcrh6 Total loading time: 0 Render date: 2024-11-30T20:21:54.126Z Has data issue: false hasContentIssue false
  • English
  • Français

Toxic Epidermal Necrolysis After Topical Intranasal Application of Mupirocin

Published online by Cambridge University Press:  02 January 2015

Sophie-Maria Praz ,
Antoine de Torrenté ,
Hervé Zender ,
Edmond Schmied ,
Charles-André Schleppy  and
Daniel Genné
Sophie-Maria Praz
Affiliation:
Department of Internal Medicine, Hôpital de la ville, La Chaux-de-Fonds, Switzerland
Antoine de Torrenté
Affiliation:
Department of Internal Medicine, Hôpital de la ville, La Chaux-de-Fonds, Switzerland
Hervé Zender
Affiliation:
Department of Internal Medicine, Hôpital de la ville, La Chaux-de-Fonds, Switzerland
Edmond Schmied
Affiliation:
Dermatology Department, Hôpital de la ville, La Chaux-de-Fonds, Switzerland
Charles-André Schleppy
Affiliation:
Department of Pharmacology, Hôpital de la ville, La Chaux-de-Fonds, Switzerland
Daniel Genné*
Affiliation:
Department of Internal Medicine, Hôpital de la ville, La Chaux-de-Fonds, Switzerland
*
Service de Médecine Interne, Hôpital de la ville, 2300 La Chaux-de-Fonds, Switzerland
Get access Rights & Permissions [Opens in a new window]

Abstract

We describe a case of toxic epidermal necrolysis after intranasal application of mupirocin in a 76-year-old woman. The drug was given for eradication of methicillin-resistant Staphylococcus aureus.

Type
Concise Communications
Information
Infection Control & Hospital Epidemiology , Volume 24 , Issue 6 , June 2003 , pp. 459 - 460
Copyright
Copyright © The Society for Healthcare Epidemiology of America 2003

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

1.Roujeau, JC, Chosidow, O, Saiag, P, Guillaume, JC. Toxic epidermal necrolysis (Lyell syndrome). J Am Acad Dermatol 1990;23:1039–1058.Google Scholar
2.Viard, I, Saurat, J-H. Inhibition of toxic epidermal necrolysis by blockade of CD95 with human intravenous immunoglobulin. Science 1998;282:490–493.CrossRefGoogle ScholarPubMed
3.Lyell, ADrug-induced toxic epidermal necrolysis. Clin Dermatol 1993;11:491–492.CrossRefGoogle ScholarPubMed
4.Roujeau, JC, Guillaume, JC, Fabre, JPToxic epidermal necrolysis (Lyell syndrome): incidence and drug etiology in France, 1981-1985. Arch Dermatol 1990;126:37–42.Google Scholar
5.Autegarden, JE, Pecquet, C, Huet, S, Bayrou, O, Leynadier, F. Anaphylactic shock after application of Chlorhexidine to unbroken skin. Contact Dermatitis 1999;40:215.CrossRefGoogle ScholarPubMed
6.Bergqvist-Karlsson, ADelayed and immediate-type hypersensibility to Chlorhexidine. Contact Dermatitis 1988;18:84–88.CrossRefGoogle Scholar
7.American Society of Health Systems Pharmacists. Mupirocin 2001. In: AHFS Drug Information 2001. Bethesda, MD: American Society of Health Systems Pharmacists; 2001:3319–3322.Google Scholar
8.Daly, BM. Bactroban allergy due to polyethylene glycol. Contact Dermatitis 1987;17:48–49.Google Scholar
9.Stenveld, HJ, Langendijk, PNJ, Bruynzeel, DPContact sensitivity to polyethylene glycols. Contact Dermatitis 1994;30:184–185.Google Scholar
10.Bajaj, AK, Gupta, SC, Chatterjee, AKSingh, KG. Contact sensitivity to polyethylene glycol. Contact Dermatitis 1990;22:291–292.Google Scholar