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Timing of Intravenous Administration Set Changes: A Systematic Review

Published online by Cambridge University Press:  02 January 2015

Donna Gillies ,
Libba O'Riordan ,
Margaret Wallen ,
Karen Rankin ,
Anne Morrison  and
Sue Nagy
Donna Gillies*
Affiliation:
The Research Development Unit, The School of Nursing, Family and Community Health, The University of Western Sydney, New South Wales, Australia
Libba O'Riordan
Affiliation:
Oncology Department, The University of Technology, Sydney, New South Wales, Australia
Margaret Wallen
Affiliation:
Research Department, The University of Technology, Sydney, New South Wales, Australia
Karen Rankin
Affiliation:
Nursing Liaison Department, The University of Technology, Sydney, New South Wales, Australia
Anne Morrison
Affiliation:
Paediatric Intensive Care Unit, The Children's Hospital at Westmead, The University of Technology, Sydney, New South Wales, Australia
Sue Nagy
Affiliation:
Faculty of Nursing, Midwifery, and Health, The University of Technology, Sydney, New South Wales, Australia School of Nursing, Family and Community Health, University of Western Sydney, New South Wales, Australia
*
The Research Development Unit, The School of Nursing, Family and Community Health, The University of Western Sydney, Locked Bag 1797, Penrith South DC, NSW 1797, Australia
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Abstract

Objective:

To determine the optimal time interval for the routine replacement of intravenous administration sets when crystalloids or parenteral nutrition are administered via a central or peripheral catheter in an acute care setting.

Design:

Systematic review of all randomized or systematically allocated controlled trials addressing the frequency of replacing intravenous administration sets.

Methods:

The Cochrane Controlled Trials Register (June 2001) and the Ovid databases (Medline, CINAHL, and CancerLit-July 2001) were searched. Bibliographies, relevant conference proceedings, and any product information were also checked for references.

Results:

Eighteen studies were selected for review. The 12 included studies were separated into 3 intravenous administration set change comparisons; 24 hours versus 48 hours or more; 48 hours versus 72 hours or more; and 72 hours versus 96 hours or more. There was good evidence that changing intravenous administration sets every 72 hours or more does not increase the risk of infusate-related bloodstream infection (BSI) in patients with central or peripheral catheters and a fair level of evidence that it does not increase the risk of catheter-related BSI. There were insufficient data regarding the incidence of BSI among patients receiving parenteral nutrition, particularly lipid-containing parenteral nutrition.

Conclusions:

It appears that intravenous administration sets containing crystalloids can be changed in patients with central or peripheral catheters every 72 hours or more without increasing the risk of BSI. However, it is not possible to conclude that intravenous administration sets containing parenteral nutrition, particularly lipid-containing parenteral nutrition, can be changed at this interval.

Type
Original Articles
Information
Infection Control & Hospital Epidemiology , Volume 25 , Issue 3 , March 2004 , pp. 240 - 250
Copyright
Copyright © The Society for Healthcare Epidemiology of America 2004

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