Hostname: page-component-586b7cd67f-t8hqh Total loading time: 0 Render date: 2024-11-30T21:39:43.507Z Has data issue: false hasContentIssue false
  • English
  • Français

Staphylococcus aureus Bloodstream Infection After Cardiac Surgery: Risk Factors and Outcome

Published online by Cambridge University Press:  21 June 2016

Christian Olsson ,
Ann Tammelin  and
Stefan Thelin
Christian Olsson*
Affiliation:
Department of Surgical Sciences, Cardiothoracic Unit, Uppsala University Hospital, Uppsala, Sweden
Ann Tammelin
Affiliation:
Department of Clinical Bacteriology, Karolinska University Hospital, Stockholm, Sweden
Stefan Thelin
Affiliation:
Department of Surgical Sciences, Cardiothoracic Unit, Uppsala University Hospital, Uppsala, Sweden
*
Thoraxcentrum, Akademiska sjukhuset, S-751 85, Uppsala, Sweden ([email protected])
Get access Rights & Permissions [Opens in a new window]

Abstract

Thirty-eight patients (10 cases and 28 controls) were included in a case-control study of Staphylococcus aureus bloodstream infection after cardiac surgery in 833 patients. All bacterial strains were found to be unique by pulsed-field gel electrophoresis. In multivariable risk-factor analysis, only valve prosthesis implantation was associated with blood-stream infection. The early and late case mortality rate was 0%.

Type
Concise Communications
Information
Infection Control & Hospital Epidemiology , Volume 27 , Issue 1 , January 2006 , pp. 83 - 85
Copyright
Copyright © The Society for Healthcare Epidemiology of America 2006

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

1.Ottino, G, De Paulis, R, Pansini, S. Major sternal wound infection after open-heart surgery: a multivariate analysis of risk factors in 2579 consecutive operations. Ann Thorac Surg 1987; 44:173–179.CrossRefGoogle Scholar
2.Bone, RC, Balk, RA, Cerra, FB, et al, for the ACCP/SCCM Consensus Conference Committee. Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. Chest 1992; 101: 1644–1655.CrossRefGoogle ScholarPubMed
3.Miranda, AG, Singh, KV, Murray, BE. DNA fingerprinting of Enterococcus faecium by pulsed-field gel electrophoresis may be a useful epidemiologic tool. J Clin Microbiol 1991; 29:2752–2757.CrossRefGoogle ScholarPubMed
4.Tammelin, A, Hambraeus, A, Ståhle, E. Mediastinitis after cardiac surgery: improvement of bacteriological diagnosis by use of multiple tissue samples and strain typing. J Clin Microbiol 2002; 40:2936–2941.CrossRefGoogle ScholarPubMed
5.Tenover, FC, Arbeit, RD, Goering, RV, et al. Interpreting chromosomal DNA restriction patterns produced by pulsed-field gel electrophoresis: criteria for bacterial strain typing. J Clin Microbiol 1995; 33:2233–2239.CrossRefGoogle ScholarPubMed
6.Loop, FD, Lytle, BW, Cosgrove, DM, et al. Sternal wound complications after isolated coronary artery bypass grafting: early and late mortality, morbidity, and cost of care. Ann Thorac Surg 1990; 49:179–187.CrossRefGoogle ScholarPubMed
7.Muñoz, P, Menasalvas, A, Bernaldo de Quirós, JCL, et al. Postsurgical mediastinitis: a case-control study. Clin Infect Dis 1997; 25:1060–1064.CrossRefGoogle ScholarPubMed
8.Ståhle, E, Tammelin, A, Bergström, R, et al. Sternal wound complications—incidence, microbiology and risk factors. Eur J Cardiothorac Surg 1997; 11:1146–1153.Google Scholar
9.Tegnell, A, Arén, C, Öhman, L. Coagulase-negative staphylococci and sternal infections after cardiac operation. Ann Thorac Surg 2000; 69:1104–1109.CrossRefGoogle ScholarPubMed
10.The Parisian Mediastinitis Study Group. Risk factors for deep sternal wound infection after sternotomy: a prospective, multicenter study. J Thorac Cardiovasc Surg 1996; 111:1200–1207.CrossRefGoogle Scholar
11.Garrison, RN, Wilson, MA. Intravenous and central catheter infections. Surg Clin North Am 1994; 74:557–570.CrossRefGoogle ScholarPubMed
12.Gottlieb, GS, Fowler, VG, Kuo Kong, L, et al. Staphylococcus aureus bacteremia in the surgical patient: a prospective analysis of 73 postoperative patients who developed Staphylococcus aureus bacteremia at a tertiary care facility. J Am Coll Surg 2000; 190:50–57.CrossRefGoogle Scholar
13.Fowler, VG, Kaye, KS, Simel, DL, et al. Staphylococcus aureus bacteremia after median sternotomy: clinical utility of blood culture results in the identification of postoperative mediastinitis. Circulation 2003; 108:73–78.CrossRefGoogle ScholarPubMed
14.Kohman, LJ, Coleman, MJ, Parker, FB. Bacteremia and sternal infection after coronary artery bypass grafting. Ann Thorac Surg 1990; 49:454–457.CrossRefGoogle ScholarPubMed
15.Lowy, FD. Staphylococcus aureus infections. N Engl J Med 1998; 339:520–532.CrossRefGoogle ScholarPubMed
16.Jakob, HG, Borneff-Lipp, M, Bach, A, et al. The endogenous pathway is a major route for deep sternal wound infection. Eur J Cardiothorac Surg 2000; 17:154–160.CrossRefGoogle Scholar
17.Von Eiff, C, Becker, K, Macha, K, et al. Nasal carriage as a source of Staphylococcus aureus bacteremia. N Engl J Med 2001; 344:11–16.CrossRefGoogle ScholarPubMed
18.Kluytmans, JAJW, Mouton, JW, Ijzerman, EPF, et al. Nasal carriage of Staphylococcus aureus as a major factor for wound infections after cardiac surgery. J Infect Dis 1995; 171:216–219.Google Scholar