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Severity of Clostridium difficile–Associated Disease (CDAD) in Allogeneic Stem Cell Transplant Recipients: Evaluation of a CDAD Severity Grading System

Published online by Cambridge University Press:  02 January 2015

Erik R. Dubberke*
Affiliation:
Division of Infectious Diseases, Washington University School of Medicine, St. Louis
Justin Sadhu
Affiliation:
Division of Infectious Diseases, Washington University School of Medicine, St. Louis
Robert Gatti
Affiliation:
University of Missouri—Kansas City School of Dentistry, Kansas City, Missouri
Kimberly A. Reske
Affiliation:
Division of Infectious Diseases, Washington University School of Medicine, St. Louis
John F. DiPersio
Affiliation:
Division of Oncology, Washington University School of Medicine, St. Louis
Steven M. Devine
Affiliation:
Division of Oncology, Washington University School of Medicine, St. Louis
Victoria J. Fraser
Affiliation:
Division of Infectious Diseases, Washington University School of Medicine, St. Louis
*
Division of Infectious Diseases, Washington University School of Medicine, Campus Box 8051, 660 S. Euclid Avenue, St. Louis, MO 63110 ([email protected])

Abstract

The purpose of this study was to develop and test a Clostridium difficile-associated disease (CDAD) grading system based on presenting symptoms in allogeneic stem cell transplant recipients. Patients with severe CDAD had significantly shorter median survival times and more adverse outcomes than patients with mild or moderate CDAD.

Type
Concise Communication
Copyright
Copyright © The Society for Healthcare Epidemiology of America 2007

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