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Risk of Clostridium difficile-Associated Disease Among Patients Receiving Proton-Pump Inhibitors in a Quebec Medical Intensive Care Unit

Published online by Cambridge University Press:  02 January 2015

Mathieu Beaulieu ,
David Williamson ,
Gilbert Pichette  and
Jean Lachaine
Mathieu Beaulieu*
Affiliation:
Université de Montréal, Hôpital du Sacre-Coeur de Montreal, Quebec, Canada
David Williamson
Affiliation:
Université de Montréal, Hôpital du Sacre-Coeur de Montreal, Quebec, Canada Pharmacy, Hôpital du Sacre-Coeur de Montreal, Quebec, Canada
Gilbert Pichette
Affiliation:
Departments of Microbiology, Hôpital du Sacre-Coeur de Montreal, Quebec, Canada
Jean Lachaine
Affiliation:
Université de Montréal, Hôpital du Sacre-Coeur de Montreal, Quebec, Canada
*
Faculty of Pharmacy, Université de Montréal, PO Box 6128, succ. Centre-ville, Montreal, Quebec, CanadaH3C 3J7 ([email protected])
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Abstract

Our study was conducted to determine whether use of gastric acid-suppressive agents increased the risk of Clostridium difficile-associated disease (CDAD) in a medical intensive care unit of one of the first hospitals to be threatened by the current CDAD epidemic in Quebec, Canada. Our findings suggest that efforts to determine risk factors for CDAD should focus on other areas, such as older age and antibiotic use.

Type
Concise Communications
Information
Infection Control & Hospital Epidemiology , Volume 28 , Issue 11 , November 2007 , pp. 1305 - 1307
Copyright
Copyright © The Society for Healthcare Epidemiology of America 2007

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