Hostname: page-component-586b7cd67f-dsjbd Total loading time: 0 Render date: 2024-11-28T00:41:35.076Z Has data issue: false hasContentIssue false

Risk Factors for Surgical Site Infection Complicating Laminectomy

Published online by Cambridge University Press:  02 January 2015

N. Deborah Friedman*
Affiliation:
Division of Infectious Diseases, Department of Medicine, Duke University Hospital, Durham, North Carolina
Daniel J. Sexton
Affiliation:
Division of Infectious Diseases, Department of Medicine, Duke University Hospital, Durham, North Carolina
Sarah M. Connelly
Affiliation:
Division of Infectious Diseases, Department of Medicine, Duke University Hospital, Durham, North Carolina
Keith S. Kaye*
Affiliation:
Division of Infectious Diseases, Department of Medicine, Duke University Hospital, Durham, North Carolina
*
International Training and Education Center on HIV, PO Box 20752, Windhoek, Namibia ([email protected])
Box 3152, DUMC, Durham, NC, 27710 ([email protected])

Abstract

Objective.

To examine risk factors for surgical site infection (SSI) following spinal surgery and to analyze the associations between a surgeon's years of operating experience and surgical specialty and patients' SSI risk.

Design.

Case-control study.

Setting.

A tertiary care facility and a community hospital in Durham, North Carolina.

Patients.

Each case patient who developed an SSI complicating laminectomy was matched with 2 noninfected control patients by hospital, year of surgery, and National Nosocomial Infection Surveillance System risk index score.

Results.

Forty-one case patients with SSI complicating laminectomy and 82 matched control patients were analyzed. Nonwhite race, diabetes and an elevated body mass index (BMI) were more common among case patients than among control patients. Subjects with a BMI greater than 35 were more likely to undergo a prolonged procedure, compared with case patients who had a BMI of 35 or less. The SSI rate for patients operated on by neurosurgeons was 28%, compared with 43% for patients operated on by orthopedic surgeons (odds ratio [OR], 0.5; P = .12). The number of years of operating experience were not associated with SSI risk. Multivariate analysis revealed diabetes (OR, 4.2 [95% confidence interval {CI}, 1.1-16.3]; P = .04), BMI greater than 35 (OR, 7.1 [95% CI, 1.8-28.3]; P = .005), and laminectomy at a level other than cervical (OR, 6.7 [95% CI, 1.4-33.3]; P = .02) as independent risk factors for SSI following laminectomy.

Conclusion.

Diabetes, obesity, and laminectomy at a level other than cervical are independent risk factors for SSI following laminectomy. Preoperative weight loss and tight perioperative control of blood glucose levels may reduce the risk of SSI in laminectomy patients.

Type
Original Articles
Copyright
Copyright © The Society for Healthcare Epidemiology of America 2007

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

1. Yuan, PS, Booth, RE Jr Albert, TJ. Nonsurgical and surgical management of lumbar spinal stenosis. Instr Course Lect 2005;54:303312.Google ScholarPubMed
2. Caliandro, P, Aulisa, L, Padua, R, et al. Quality of life, clinical and neurophysiological picture in patients operated on for lumbar stenosis. Acta Neurochir 2005;92(suppl):143146.CrossRefGoogle ScholarPubMed
3. Lindholm, TS, Pylkkanen, P. Discitis following removal of intervertebral disc. Spine 1982;7:618622.Google Scholar
4. Massie, JB, Heller, JG, Abitbol, JJ, McPherson, D, Garfin, SR. Postoperative posterior spinal wound infections. Clin Orthop Relat Res 1992;284:99108.CrossRefGoogle Scholar
5. Perry, JW, Montgomerie, JZ, Swank, S, Gilmore, DS, Maeder, K. Wound infections following spinal fusion with posterior segmental spinal instrumentation. Clin Infect Dis 1997;24:558561.Google Scholar
6. Ramirez, LF, Thisted, R. Complications and demographic characteristics of patients undergoing lumbar discectomy in community hospitals. Neurosurgery 1989;25:226230.CrossRefGoogle ScholarPubMed
7. Fernand, R, Lee, CK. Postlaminectomy disc space infection: a review of the literature and a report of three cases. Clin Orthop Relat Res 1986;209:215218.CrossRefGoogle Scholar
8. Luer, MS, Hatton, J. Appropriateness of antibiotic selection and use in laminectomy and microdiskectomy. Am J Hosp Pharm 1993;50:667670.Google Scholar
9. Ehrenkranz, NJ. Surgical wound infection occurrence in clean operations; risk stratification for interhospital comparisons. Am J Med 1981;70:909914.Google Scholar
10. National Nosocomial Infections Surveillance (NNIS) System Report. Data summary from January 1992 through June 2004, issued October 2004. Am J Infect Control 2004;32:470485.Google Scholar
11. Thibodeau, AA. Closed space infection following removal of lumbar intervertebral disc. Clin Neurosurg 1966;14:337360.Google Scholar
12. Apisarnthanarak, A, Jones, M, Waterman, BM, Carroll, CM, Bernardi, R, Fraser, VJ. Risk factors for spinal surgical-site infections in a community hospital: a case-control study. Infect Control Hosp Epidemiol 2003;24:3136.CrossRefGoogle Scholar
13. Capen, DA, Calderone, RR, Green, A. Perioperative risk factors for wound infections after lower back fusions. Orthop Clin North Am 1996;27:8386.Google Scholar
14. Klein, JD, Hey, LA, Yu, CS, et al. Perioperative nutrition and postoperative complications in patients undergoing spinal surgery. Spine 1996;21:26762682.CrossRefGoogle ScholarPubMed
15. Polk, HC Jr Simpson, CJ, Simmons, BP, Alexander, JW. Guidelines for prevention of surgical wound infection. Arch Surg 1983;118:12131217.CrossRefGoogle ScholarPubMed
16. Wimmer, C, Gluch, H, Franzreb, M, Ogon, M. Predisposing factors for infection in spine surgery: a survey of 850 spinal procedures. J Spinal Disord 1998;11:124128.Google Scholar
17. Horan, TC, Gaynes, RP, Martone, WJ, Jarvis, WR, Emori, TG. CDC definitions of nosocomial surgical site infection, 1992: a modification of the CDC definitions of surgical wound infections. Infect Control Hosp Epidemiol 1992;13:606608.CrossRefGoogle ScholarPubMed
18. Kirkland, KB, Briggs, JP, Trivette, SL, Wilkinson, WE, Sexton, DJ. The impact of surgical-site infections in the 1990s: attributable mortality, excess length of hospitalization, and extra costs. Infect Control Hosp Epidemiol 1999;20:725730.Google Scholar
19. Culver, DH, Horan, TC, Gaynes, RP, et al. Surgical wound infection rates by wound class, operative procedure, and patient risk index. Am J Med 1991;91(suppl 3B):S152S157.CrossRefGoogle ScholarPubMed
20. Delgado-Rodriguez, M, Sillero-Arenas, M, Medina-Cuadros, M, Martinez-Gallego, G. Nosocomial infections in surgical patients: comparison of two measures of intrinsic patient risk. Infect Control Hosp Epidemiol 1997;18:1923.Google Scholar
21. Classen, DC, Evans, RS, Pestotnik, SL, Horn, SD, Menlove, RL, Burke, JP. The timing of prophylactic administration of antibiotics and the risk of surgical-wound infection. N Engl J Med 1992;326:281286.Google Scholar
22. Kuo, CH, Wang, ST, Yu, WK, Chang, MC, Liu, CL, Chen, TH. Postoperative spinal deep wound infection: a six-year review of 3230 selective procedures. J Chin Med Assoc 2004;67:398402.Google ScholarPubMed
23. Olsen, MA, Mayfield, J, Lauryssen, C, et al. Risk factors for surgical site infection in spinal surgery. J Neurosurg 2003;98(suppl 2):149155.Google Scholar
24. Brashers, VL, Davey, SS. Alterations of pulmonary function. In: McCance, KL, Huether, SE, eds. Pathophysiology: The Biologic Basis for Disease in Adults and Children. 3rd ed. St. Louis: Mosby, 1998:11581200.Google Scholar
25. Groszek, DM. Promoting wound healing in the obese patient. AORN J 1982;35:11321138.Google Scholar
26. Wilson, JA, Clark, JJ. Obesity: impediment to postsurgical wound healing. Adv Skin Wound Care 2004;17:426435.Google Scholar
27. Wisse, BE. The inflammatory syndrome: the role of adipose tissue cytokines in metabolic disorders linked to obesity. J Am Soc Nephrol 2004;15:27922800.CrossRefGoogle ScholarPubMed
28. Airaksinen, O, Herno, A, Turunen, V, Saari, T, Suomlainen, O. Surgical outcome of 438 patients treated surgically for lumbar spinal stenosis. Spine 1997;22:22782283.CrossRefGoogle ScholarPubMed
29. Kawaguchi, Y, Matsui, H, Ishihara, H, Gejo, R, Yasuda, T. Surgical outcome of cervical expansive laminoplasty in patients with diabetes mellitus. Spine 2000;25:551555.Google Scholar
30. Simpson, JM, Silveri, CP, Balderston, RA, Simeone, FA, An, HS. The results of operations on the lumbar spine in patients who have diabetes mellitus. J Bone Joint Surg 1993;75:18231829.Google Scholar
31. Harrington, G, Russo, P, Spelman, D, et al. Surgical-site infection rates and risk factor analysis in coronary artery bypass graft surgery. Infect Control Hosp Epidemiol 2004;25:472476.Google Scholar
32. Peersman, G, Laskin, R, Davis, J, Peterson, M. Infection in total knee replacement: a retrospective review of 6489 total knee replacements. Clin Orthop Relat Res 2001;392:1523.Google Scholar
33. Wilson, SJ, Sexton, DJ. Elevated preoperative fasting serum glucose levels increase the risk of postoperative mediastinitis in patients undergoing open heart surgery. Infect Control Hosp Epidemiol 2003;24:776778.CrossRefGoogle ScholarPubMed
34. Harger, JH, English, DH. Selection of patients for antibiotic prophylaxis in cesarean sections. Am J Obstet Gynecol 1981;141:752758.Google Scholar
35. Soltau, JB, Rothman, RF, Budenz, DL, et al. Risk factors for glaucoma filtering bleb infections. Arch Ophthal 2000;118:338342.Google Scholar
36. Watts, DH, Lambert, JS, Stiehm, ER, et al. Complications according to mode of delivery among human immunodeficiency virus-infected women with CD4 lymphocyte counts of ≤500/μL. Am J Obstet Gynecol 2000;183:100107.Google Scholar
37. Abbott, KC, Agodoa, LY. Etiology ofbacterial septicemia in chronic dialysis patients in the United States. Clin Nephrol 2001;56:124131.Google Scholar
38. Knight, BP, Oral, H, Chugh, A, et al. Effects of operator experience on the outcome and duration of pulmonary vein isolation procedures for atrial fibrillation. Am J Cardiol 2003;91:673677.Google Scholar