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Risk Factors for Healthcare-Associated, Laboratory-Confirmed Influenza in Hospitalized Pediatric Patients: A Case-Control Study

Published online by Cambridge University Press:  02 January 2015

Kateri H. Leckerman
Affiliation:
Division of Infectious Diseases, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania
Eileen Sherman
Affiliation:
Department of Infection Prevention and Control, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania
Jillian Knorr
Affiliation:
Department of Infection Prevention and Control, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania
Theoklis E. Zaoutis
Affiliation:
Division of Infectious Diseases, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania Center for Pediatric Clinical Effectiveness, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania
Susan E. Coffin*
Affiliation:
Division of Infectious Diseases, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania Department of Infection Prevention and Control, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania Center for Pediatric Clinical Effectiveness, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania
*
Children's Hospital of Philadelphia, 34th Street and Civic Center Boulevard, Philadelphia, PA 19104 ([email protected])

Abstract

We conducted a case-control study of 46 hospitalized pediatric patients with healthcare-associated laboratory-confirmed influenza (HA-LCI). We sought to determine the characteristics and outcomes of children with HA-LGI and to identify risk factors for HA-LCI. Although we failed to identify any differences in clinical exposures during the 3 days prior to onset of HA-LCI, multivariate analysis showed that asthma was an independent risk factor for HA-LCI (odds ratio, 3.49 [95% confidence interval, 1.25–9.75]).

Type
Concise Communications
Copyright
Copyright © The Society for Healthcare Epidemiology of America 2010

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References

1. Weingarten, S, Friedlander, M, Rascon, D, Ault, M, Morgan, M, Meyer, RD. Influenza surveillance in an acute-care hospital. Arch Intern Med 1988;148:113116.CrossRefGoogle Scholar
2. Morens, D, Rash, VM. Lessons from a nursing home outbreak of influenza A. Infect Control Hosp Epidemiol 1995;16:275280.CrossRefGoogle ScholarPubMed
3. Serwint, JR, Miller, RM, Korsch, BM. Influenza type A and B infections in hospitalized pediatric patients: who should be immunized? Am J Dis Child 1991;145:623626.Google Scholar
4. Hall, C, Douglas, R. Nosocomial influenza infection as a cause of intercurrent fevers in infants. Pediatrics 1975;55:673677.Google Scholar
5. Sagrera, X, Ginovart, G, Raspall, F, et al. Outbreaks of influenza A virus infection in neonatal intensive care units. Pediatr Infect Dis J 2002;21:196200.CrossRefGoogle ScholarPubMed
6. Bridges, CB, Kuehnert, MJ, Hall, CB. Transmission of influenza: implications for control in health care settings. Clin Infect Dis 2003;37:10941101.Google ScholarPubMed
7. Blachere, FM, Lindsley, WG, Pearce, TA, et al. Measurement of airborne influenza virus in a hospital emergency department. Clin Infect Dis 2009;48(4:438440.Google Scholar
8. Serwint, JR, Miller, RM. Why diagnose influenza infections in hospitalized pediatric patients? Pediatr Infect Dis J 1993;12(3:200204.Google Scholar
9. Wenzel, RP, Deal, EC, Hendley, JO. Hospital-acquired respiratory illness on a pediatric ward. Pediatrics 1977;60(3:367371.Google Scholar
10. Keren, R, Zaoutis, T, Bridges, C, et al. Neurological and neuromuscular disease as a risk factor for respiratory failure in children hospitalized with influenza infection. JAMA 2005;294:21882194.Google Scholar