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Risk Factors and Outcomes of Influenza A (H3N2) Pneumonia in an Area Where Avian Influenza (H5N1) Is Endemic

Published online by Cambridge University Press:  02 January 2015

Anucha Apisarnthanarak ,
Pilaipan Puthavathana  and
Linda M. Mundy
Anucha Apisarnthanarak*
Affiliation:
Division of Infectious Diseases, Department of Medicine, Thammasart University Hospital, Pratumthani
Pilaipan Puthavathana
Affiliation:
Department of Microbiology, Siriraj Hospital, Bangkok, Thailand
Linda M. Mundy
Affiliation:
Saint Louis University School of Public Health, St. Louis, Missouri
*
Division of Infectious Diseases, Dept. of Medicine, Thammasart University Hospital, Pratumthani, Thailand, 12000 ([email protected])
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Abstract

We conducted a cohort study to identify the risks and outcomes of influenza A (H3N2) pneumonia. Of the 145 patients studied, 10 (7%) had influenza A pneumonia. Logistic regression identified multiple comorbidities (P<.001) and diarrhea at the initial presentation (P = .001) as associated risks. Infection with influenza A (P = .01) and receipt of inadequate antimicrobial therapy (P = .005) were predictors of mortality.

Type
Concise Communication
Information
Infection Control & Hospital Epidemiology , Volume 28 , Issue 4 , April 2007 , pp. 479 - 482
Copyright
Copyright © The Society for Healthcare Epidemiology of America 2007

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References

1.Monto, AS. Individual and community impact of influenza. Pharmaco-economics 1999;16:1–6.Google Scholar
2.Cox, NJ, Subbarao, K. Influenza. Lancet 1999;354:1277–1282.CrossRefGoogle ScholarPubMed
3.World Health Organization. Cumulative number of confirmed human cases of avian influenza A (H5N1) reported to WHO, 13 February 2006. Available at: http://www.who.int/csr/diseases/avian_influenza/country/cases_table _2006_01_25_/en/index.html. Accessed May 26, 2006.Google Scholar
4.Simmerman, IM, Thawatsupha, P, Kingnate, D, Fukuda, K, Chaising, A, Dowell, SF. Influenza in Thailand: a case study for middle income countries. Vaccine 2004;23:182–187.CrossRefGoogle ScholarPubMed
5.Apisarnthanarak, A, Puthavathana, P, Kitphati, R, et al.Avian influenza H5N1 screening of intensive care unit patients with community-acquired pneumonia. Emerg Infect Dis 2006;12:1766–1769.CrossRefGoogle ScholarPubMed
6.Niederman, MS, Bass, JB JrCampbell, GD, et al.Guidelines for the initial management of adults with community-acquired pneumonia: diagnosis, assessment of severity, and initial antimicrobial therapy. Am Rev Respir Dis 1993;148:1418–1426.CrossRefGoogle ScholarPubMed
7.Kollef, MH. Inadequate antimicrobial treatment: an important determinant of outcome for hospitalized patients. Clin Infect Dis 2000;31(suppl 4):S131–S138.CrossRefGoogle ScholarPubMed
8.Apisarnthanarak, A, Mundy, LM. Etiology of community-acquired pneumonia. Clin Chest Med 2005;26:47–55.Google Scholar
9.Poddar, SK. Influenza virus types and subtypes detection by single step single tube multiplex reverse transcription-polymerase chain reaction (RT-PCR) and agarose gel electrophoresis. J Virol Methods 2002;99:63–70.Google Scholar
10.World Health Organization (WHO). Collaborating Centre for Reference and Research on Influenza: Annual Report. WHO: Melbourne, Australia; 2002. Available at: http://www.influenzacentre.org. Accessed May 26, 2006.Google Scholar
11.Bartlett, IG, Mundy, LM. Community acquired pneumonia. N Engl J Med 1995;333:1618–1624.Google Scholar
12.Ruiz, M, Ewig, S, Marcos, M, et al.Etiology of community-acquired pneumonia: impact of age, comorbidity, and severity. Am J Resp Crit Care Med 1999;160:397–405.Google Scholar
13.Wattanthum, A, Chaoprosong, C, Nunthapisud, P, et al.Community-acquired pneumonia in Southeast Asia: the microbial differences between ambulatory and hospitalized patients. Chest 2003;123:1512–1519.Google Scholar