Hostname: page-component-586b7cd67f-t7fkt Total loading time: 0 Render date: 2024-11-30T20:31:47.893Z Has data issue: false hasContentIssue false
  • English
  • Français

Preventing Staphylococcal Infections by Eradicating Nasal Carriage of Staphylococcus aureus: Proceeding With Caution

Published online by Cambridge University Press:  02 January 2015

John M. Boyce
Rights & Permissions [Opens in a new window]

Abstract

An abstract is not available for this content so a preview has been provided. As you have access to this content, a full PDF is available via the ‘Save PDF’ action button.
Image of the first page of this content. For PDF version, please use the ‘Save PDF’ preceeding this image.'
Type
Editorial
Information
Infection Control & Hospital Epidemiology , Volume 17 , Issue 12 , December 1996 , pp. 775 - 779
Copyright
Copyright © The Society for Healthcare Epidemiology of America 1996

References

1. Wenzel, RP, Perl, TM. The significance of nasal carriage of Staphylococcus aureus and the incidence of postoperative wound infection. J Hosp Infect 1995;31:13–24.CrossRefGoogle ScholarPubMed
2. Kluytmans, JAJW, Mouton, JW, Ijzerman, EPF, et al. Nasal carriage of Staphylococcus aureus as a major risk factor for wound infections after cardiac surgery. J Infect Dis 1995;171:216–219.CrossRefGoogle ScholarPubMed
3. Yu, VL, Goetz, A, Wagener M, , et al. Staphylococcus aureus nasal carriage and infection in patients on hemodialysis. N Engl J Med 1986;315:91–96.CrossRefGoogle ScholarPubMed
4. Glowacki, LS, Hodsman, AB, Hammerberg, O, et al. Surveillance and prophylactic intervention of Staphylococcus aureus nasal colonization in a hemodialysis unit. Am J Nephrol 1994;14:9–13.CrossRefGoogle Scholar
5. Boelaert, JR, VanLanduyt, HW, Gordts, BZ, DeBaere, YA, Messer, SA, Herwaldt, LA. Nasal and cutaneous carriage of Staphylococcus aureus in hemodialysis patients—the effect of nasal mupirocin. Infect Control Hosp Epidemiol 1996;17:809–811.CrossRefGoogle ScholarPubMed
6. Sewell, CM, Clarridge, J, Lacke, C, Weinman, EJ, Young, EJ. Staphylococcal nasal carriage and subsequent infection in peritoneal dialysis patients. JAMA 1982;248:1493–1495.CrossRefGoogle ScholarPubMed
7. Kim, D, Tapson, J, Wu, G, Khanna, R, Vas, SI, Oreopoulos, DG. Staphylococcus aureus peritonitis in patients on continuous ambulatory peritoneal dialysis. Trans Am Soc Artif Intern Organs 1984;30:494–497.Google Scholar
8. Davies, SJ, Ogg, CS, Cameron, JS, Poston, S, Noble, WC. Staphylococcus aureus nasal carriage, exit-site infection and catheter loss in patients treated with continuous ambulatory peritoneal dialysis (CAPD). Perit Dial Int 1989;9:61–64.CrossRefGoogle Scholar
9. Sesso, R, Draibe, S, Castelo, A, et al. Staphylococcus aureus skin carriage and development of peritonitis in patients on continuous ambulatory peritoneal dialysis. Clin Nephrol 1989;31:264–268.Google ScholarPubMed
10. Luzar, MA, Coles, GA, Faller, B, et al. Staphylococcus aureus nasal carriage and infection in patients on continuous ambulatory peritoneal dialysis. N Engl J Med 1990;322:505–509.CrossRefGoogle ScholarPubMed
11. Blowey, DL, Warady, BA, McFarland, KS. The treatment of Staphylococcus aureus nasal carriage in pediatric peritoneal dialysis patients. Adv Perit Dial 1994;10:297–299.Google ScholarPubMed
12. Piraino, B, Perlmutter, JA, Holley, JL, Bernardini, J. Staphylococcus aureus peritonitis is associated with Staphylococcus aureus nasal carriage in peritoneal dialysis patients. Perit Dial Int 1993;13(suppl 2):332–334.CrossRefGoogle ScholarPubMed
13. Lye, WC, Leong, SO, vanderStratten, J, Lee, EJ. Staphylococcus aureus CAPD-related infections are associated with nasal carriage. Adv Perit Dial 1994;10:163–165.Google ScholarPubMed
14. Boelaert, JR, DeSmedt, RA, DeBaere, YA, et al. The influence of calcium mupirocin nasal ointment on the incidence of Staphylococcus aureus infections in haemodialysis patients. Nephrol Dial Transplant 1989;4:278–281.CrossRefGoogle ScholarPubMed
15. Ena, J, Boelaert, JR, Boyken, LD, VanLanduyt, HW, Godard, CA, Herwaldt, LA. Epidemiology of Staphylococcus aureus infections in patients on hemodialysis. Infect Control Hosp Epidemiol 1994;15:78–81.CrossRefGoogle ScholarPubMed
16. Herwaldt, LA, Boyken, LD, Coffman, S. Epidemiology of S aureus (SA) nasal carriage in patients (Pts) on continuous ambulatory peritoneal dialysis (CAPD) who were in a multi-center trial of mupirocin (M). In: Program and Abstracts of the 36th Interscience Conference on Antimicrobial Agents and Chemotherapy; New Orleans, LA; September 1996; Abstract J78.Google Scholar
17. Weinke, T, Schiller, R, Fehrenbach, FJ, Pohle, HD. Association between Staphylococcus aureus nasopharyngeal colonization and septicemia in patients infected with the human immunodeficiency virus. Eur J Clin Microbiol Infect Dis 1992;11:985–989.CrossRefGoogle ScholarPubMed
18. Pujol, M, Pena, C, Pallares, R, et al. Nosocomial Staphylococcus aureus bacteremia among nasal carriers of methicillin-resistant and methicillin-susceptible strains. Am J Med 1996;100:509–516.CrossRefGoogle ScholarPubMed
19. Talon, D, Rouget, C, Cailleaux, V, et al. Nasal carriage of Staphylococcus aureus and cross-contamination in a surgical intensive care unit: efficacy of mupirocin ointment. J Hosp Infect 1995;30:39–49.CrossRefGoogle Scholar
20. Mest, DR, Wong, DH, Shimoda, KJ, Mulligan, ME, Wilson, SE. Nasal colonization with methicillin-resistant Staphylococcus aureus on admission to the surgical intensive care unit increases the risk of infection. Anesth Analg 1994;78:644–650.CrossRefGoogle Scholar
21. Boyce, JM. Methicillin-resistant Staphylococcus aureus in hospitals and long-term care facilities: microbiology, epidemiology, and preventive measures. Infect Control Hosp Epidemiol 1992;13:725–737.CrossRefGoogle ScholarPubMed
22. Casewell, MW, Hill, RLR. Elimination of nasal carriage of Staphylococcus aureus with mupirocin (‘pseudomonic acid’)—a controlled trial. J Antimicrob Chemother 1986;17:365–372.CrossRefGoogle ScholarPubMed
23. Reagan, DR, Doebbeling, BN, Pfaller, MA, et al. Elimination of coincident Staphylococcus aureus nasal and hand carriage with intranasal application of mupirocin calcium ointment. Ann Intern Med 1991;114:101–106.CrossRefGoogle ScholarPubMed
24. Doebbeling, BN, Breneman, DL, Neu, HC, et al. Elimination of Staphylococcus aureus nasal carriage in health care workers: analysis of six clinical trials with calcium mupirocin ointment. Clin Infect Dis 1993;17:466–474.CrossRefGoogle ScholarPubMed
25. Combined Working Party. Revised guidelines for the control of epidemic methicillin-resistant Staphylococcus aureus . J Hosp Infect 1990;16:351–377.CrossRefGoogle Scholar
26. Boyce, JM, Jackson, MM, Pugliese, G, et al. Methicillin-resistant Staphylococcus aureus (MRSA): a briefing for acute care hospitals and nursing facilities. Infect Control Hosp Epidemiol 1994;15:105–115.CrossRefGoogle ScholarPubMed
27. Working Group on Infection Prevention. Management Policy for Methicillin-Resistant Staphylococcus aureus. Leiden, The Netherlands: Working Group on Infection Prevention; 1995:1–8.Google Scholar
28. Kluytmans, JAJW, Mouton, JW, VandenBergh, MFQ, et al. Reduction of surgical-site infections in cardiothoracic surgery by elimination of nasal carriage of Staphylococcus aureus. Infect Control Hosp Epidemiol 1996;17:780–785.CrossRefGoogle ScholarPubMed
29. VandenBergh, MFQ, Kluytmans, JAJW, van Hout, BA, et al. Cost-effectiveness of perioperative mupirocin nasal ointment in cardiothoracic surgery. Infect Control Hosp Epidemiol 1996;17:786–792.CrossRefGoogle ScholarPubMed
30. Boelaert, JR, VanLanduy, HW, Godard, CA, et al. Nasal mupirocin ointment decreases the incidence of Staphylococcus aureus bacteraemias in haemodialysis patients. Nephrol Dial Transplant 1993;8:235–239.Google ScholarPubMed
31. Holton, DL, Nicolle, LE, Diley, D, Bernstein, K. Efficacy of mupirocin nasal ointment in eradication of Staphylococcus aureus nasal carriage in chronic haemodialysis patients. J Hosp Infect 1991;17:133–137.CrossRefGoogle Scholar
32. Kluytmans, J, Manders, MAAJ, vanBommel, E, Verbrugh, H. Elimination of nasal carriage of Staphylococcus aureus in hemodialysis patients. Infect Control Hosp Epidemiol 1996;17:793–797.CrossRefGoogle ScholarPubMed
33. Boelaert, JR, De Baere, YA, Geernaert, MA, Godard, CA, VanLanduy, HW. The use of nasal mupirocin ointment to prevent Staphylococcus aureus bacteraemias in haemodialysis patients: an analysis of cost-effectiveness. J Hosp Infect 1991;19(suppl B):41–46.CrossRefGoogle ScholarPubMed
34. Bloom, BS, Fendrick, AM, Chernew, ME, Patel, P. Clinical and economic effects of mupirocin calcium on preventing Staphylococcus aureus infection in hemodialysis patients: a decision analysis. Am J Kidney Dis 1996;27:687–694.CrossRefGoogle ScholarPubMed
35. Perez-Fontan, M, Garcia-Falcon, T, Rosales, M, et al. Treatment of Staphylococcus aureus nasal carriers in continuous ambulatory peritoneal dialysis with mupirocin: long-term results. Am J Kidney Dis 1993;22:708–712.CrossRefGoogle ScholarPubMed
36. Bernardini, J, Piraino, B, Holley, J, Johnston, JR, Lutes, R. A randomized trial of Staphylococcus aureus prophylaxis in peritoneal dialysis patients: mupirocin calcium ointment 2% applied to the exit site versus cyclic oral rifampin. Am J Kidney Dis 1996;27:695–700.CrossRefGoogle Scholar
37. Swartz, R, Messana, J, Starmann, B, Weber, M, Reynolds, J. Preventing Staphylococcus aureus infection during chronic peritoneal dialysis. J Am Soc Nephrol 1991;2:1085–1091.CrossRefGoogle ScholarPubMed
38. Coovadia, YM, Bhana, RH, Johnson, AP, Haffejee, I, Marples, RR. A laboratory-confirmed outbreak of rifampicin-methicillin resistant Staphylococcus aureus (RMRSA) in a newborn nursery. J Hosp Infect 1989;14:303–312.CrossRefGoogle Scholar
39. Gaynes, R, Marosok, R, Mowry-Hanley, J, et al. Mediastinitis following coronary artery bypass surgery: a 3-year review. J Infect Dis 1991;163:117–121.CrossRefGoogle ScholarPubMed
40. Boyce, JM, Opal, SM, Potter-Bynoe, G, Medeiros, AA. Spread of methicillin-resistant Staphylococcus aureus in a hospital after exposure to a health care worker with chronic sinusitis. Clin Infect Dis 1993;17:496–504.CrossRefGoogle Scholar
41. Sherertz, RJ, Reagan, DR, Hampton, KD, et al. A cloud adult: the Staphylococcus aureus-virus interaction revisited. Ann Intern Med 1996;124:539–547.CrossRefGoogle ScholarPubMed
42. Meier, PA, Carter, CD, Wallace, SE, Hollis, RJ, Pfaller, MA, Herwaldt, LA. Eradication of methicillin-resistant Staphylococcus aureus (MRSA) from the burn unit at a tertiary medical center. Infect Control Hosp Epidemiol 1996;17:798–802.Google Scholar
43. Wenzel, RP, Nettleman, MD, Jones, RN, Pfaller, MA. Methicillin-resistant Staphylococcus aureus: implications for the 1990s and effective control measures. Am J Med 1991;91(suppl 3B):221S-227S.CrossRefGoogle ScholarPubMed
44. Boelaert, JR, VanLanduyt, HW, DeBaere, YA, et al. Nasal mupirocin decreases the incidence of Staphylococcus aureus bacteremia in hemodialysis: a five-year study. In: Program and Abstracts of the 35th Interscience Conference on Antimicrobial Agents and Chemotherapy; San Francisco, CA; September 1995. Abstract J122.Google Scholar
45. Marples, RR, Speller, DCE, Cookson, BD. Prevalence of mupirocin resistance in Staphylococcus aureus . J Hosp Infect 1995;29:153–161.CrossRefGoogle ScholarPubMed
46. Kauffman, CA, Terpenning, MS, He, X, et al. Attempts to eradicate methicillin-resistant Staphylococcus aureus from a long-term-care facility with the use of mupirocin ointment. Am J Med 1993;94:371–378.CrossRefGoogle ScholarPubMed
47. Layton, MC, Perez, M, Heald, P, Patterson, JE. An outbreak of mupirocin-resistant Staphylococcus aureus on a dermatology ward associated with an environmental reservoir. Infect Control Hosp Epidemiol 1993;14:369–375.CrossRefGoogle ScholarPubMed
48. Bradley, SF, Ramsey, MA, Morton, TM, Kauffman, CA. Mupirocin resistance: clinical and molecular epidemiology. Infect Control Hosp Epidemiol 1995;16:354–358.CrossRefGoogle ScholarPubMed
49. Miller, MA, Dascal, A, Portnoy, J, Mendelson, J. Development of mupirocin resistance among methicillin-resistant Staphylococcus aureus (MRSA) after widespread use of nasal mupirocin ointment. Infect Control Hosp Epidemiol 1996;17:812–814.CrossRefGoogle ScholarPubMed
50. dos Santos, KRN, Fonseca, LDS, Filho, PPG. Emergence of high-level mupirocin resistance in methicillin-resistant Staphylococcus aureus isolated from Brazilian university hospitals. Infect Control Hosp Epidemiol 1996;17:814–816.CrossRefGoogle Scholar