Hostname: page-component-586b7cd67f-vdxz6 Total loading time: 0 Render date: 2024-11-28T08:26:42.311Z Has data issue: false hasContentIssue false
  • English
  • Français

Predictors of Mortality Among Patients With Community-Onset Infection Due to Extended-Spectrum β-Lactamase-Producing Escherichia coli in Thailand

Published online by Cambridge University Press:  02 January 2015

Anucha Apisarnthanarak ,
Patarachai Kiratisin ,
Piyawan Saifon ,
Rungrueng Kitphati ,
Surang Dejsirilert  and
Linda M. Mundy
Anucha Apisarnthanarak*
Affiliation:
Division of Infectious Diseases, Faculty of Medicine, Thammasart University Hospital, Pratumthani, Thailand
Patarachai Kiratisin
Affiliation:
Department of Microbiology, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok, Thailand
Piyawan Saifon
Affiliation:
Department of Microbiology, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok, Thailand
Rungrueng Kitphati
Affiliation:
Division of Science, Thai National Institute of Health, Nonthaburi, Thailand
Surang Dejsirilert
Affiliation:
Division of Science, Thai National Institute of Health, Nonthaburi, Thailand
Linda M. Mundy
Affiliation:
Saint Louis University School of Public Health, Saint Louis, Missouri
*
Division of Infectious Diseases, Faculty of Medicine, Thammasart University Hospital, Pratumthani, Thailand12120 ([email protected])
Get access Rights & Permissions [Opens in a new window]

Abstract

A matched case-control study was performed to identify predictors of mortality among patients (n = 46) with community-onset infections due to extended-spectrum β-lactamase-producing Escherichia coli in Thailand. The crude mortality rate was 30%. By multivariable analysis, community-onset bloodstream infection due to extended-spectrum β-lactamase-producing E. coli was the sole predictor of mortality (adjusted odds ratio, 41.3 [95% confidence interval, 4.3-69.4]; P = .001).

Type
Concise Communications
Information
Infection Control & Hospital Epidemiology , Volume 29 , Issue 1 , January 2008 , pp. 80 - 82
Copyright
Copyright © The Society for Healthcare Epidemiology of America 2008

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

1.Colodner, R, Rock, W, Chazan, B, et al.Risk factors for the development of extended-spectrum β-lactamase-producing bacteria in nonhospitali-zed Patients. Eur J Clin Microbiol Infect Dis 2004;23:163–167.CrossRefGoogle ScholarPubMed
2.Calbo, E, Romany, V, Xercavins, M, et al.Risk factors for community-onset urinary tract infections due to Escherichia coli harboring extended-spectrum β-lactamases. J Antimicrob Chemother 2005;57:780–783.Google Scholar
3.Apisarnthanarak, A, Kiratisin, P, Saifon, P, Kitphati, R, Dejsirilert, S, Mundy, LM. Clinical and molecular epidemiology of community-onset extended spectrum β-lactamase producing Escherichia coli in Thailand: a case-case-control study. Am J Infect Control 2007;35:606–612.CrossRefGoogle ScholarPubMed
4.Rodriguez-Bano, J, Navarro, MD, Romero, L, et al.Bacteremia due to extended-spectrum beta-lactamase-producing Escherichia coli in the CTX-M era: a new clinical challenge. Clin Infect Dis 2006;43:1407–1414.CrossRefGoogle Scholar
5.Dejsirilert, S, Apisarnthanarak, A, Kitphati, R, et al.The status of antimicrobial resistance in Thailand among gram-negative pathogens in bloodstream infections: NARST data, 2000-2003. In: Program and abstracts of the 9th Western Pacific Congress on Chemotherapy and Infectious Diseases (Bangkok). 2004:185 (Abstract FP-A-3).Google Scholar
6.Apisarnthanarak, A, Danchaivijitr, S, Bailey, TC, et al.Inappropriate antibiotic use in a tertiary care center in Thailand: an incidence study and review of experience in Thailand. Infect Control Hosp Epidemiol 2006;27:416–420.Google Scholar
7.Garner, JS, Jarvis, WR, Emori, TG, et al.CDC definitions for nosocomial infections, 1988. Am J Infect Control 1988;16:128–140.Google Scholar
8.Kollef, MH. Inadequate antimicrobial treatment: an important determinant of outcome for hospitalized Patients. Clin Infect Dis 2000;31(suppl 4):S131–S138.Google Scholar
9.Clinical and Laboratory Standards Institute (CLSI). Performance Standards for Antimicrobial Susceptibility Testing: Sixteenth Informational Supplement. Wayne, PA: CLSI; 2006:M100–S16.Google Scholar
10.Harris, AD, Samore, MH, Lipsitch, M, Kaye, KS, Perencevich, E, Carmeli, Y. Control-group selection importance in studies of antimicrobial resistance: examples applied to Pseudomonas aeruginosa, enterococci, and Escherichia coli. Clin Infect Dis 2002;34:1558–1563.CrossRefGoogle ScholarPubMed