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Population-based assessment of patient and provider characteristics influencing pediatric outpatient antibiotic use in a high antibiotic-prescribing state

Published online by Cambridge University Press:  15 January 2020

Sophie E. Katz Open the ORCID record for Sophie E. Katz [Opens in a new window] ,
Milner Staub ,
Youssoufou Ouedraogo ,
Christopher D. Evans ,
Marion A. Kainer ,
Marie R. Griffin  and
Ritu Banerjee
Sophie E. Katz*
Affiliation:
Department of Pediatrics, Vanderbilt University Medical Center, Nashville, Tennessee
Milner Staub
Affiliation:
Veterans’ Health Administration, Tennessee Valley Healthcare System, Geriatric Research, Education and Clinical Center (GRECC), Nashville, Tennessee Division of Infectious Diseases, Vanderbilt University Medical Center, Nashville, Tennessee
Youssoufou Ouedraogo
Affiliation:
Healthcare Associated Infections and Antimicrobial Resistance Program, Tennessee Department of Health, Nashville, TN
Christopher D. Evans
Affiliation:
Healthcare Associated Infections and Antimicrobial Resistance Program, Tennessee Department of Health, Nashville, TN
Marion A. Kainer
Affiliation:
Healthcare Associated Infections and Antimicrobial Resistance Program, Tennessee Department of Health, Nashville, TN
Marie R. Griffin
Affiliation:
Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee Department of Health Policy, Vanderbilt University Medical Center, Nashville, Tennessee
Ritu Banerjee
Affiliation:
Department of Pediatrics, Vanderbilt University Medical Center, Nashville, Tennessee
*
Author for correspondence: Sophie E. Katz, E-mail: [email protected]
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Abstract

Objective:

To identify patient and provider characteristics associated with high-volume antibiotic prescribing for children in Tennessee, a state with high antibiotic utilization.

Design:

Cross-sectional, retrospective analysis of pediatric (aged <20 years) outpatient antibiotic prescriptions in Tennessee using the 2016 IQVIA Xponent (formerly QuintilesIMS) database.

Methods:

Patient and provider characteristics, including county of prescription fill, rural versus urban county classification, patient age group, provider type (nurse practitioner, physician assistant, physician, or dentist), physician specialty, and physician years of practice were analyzed.

Results:

Tennessee providers wrote 1,940,011 pediatric outpatient antibiotic prescriptions yielding an antibiotic prescribing rate of 1,165 per 1,000 population, 50% higher than the national pediatric antibiotic prescribing rate. Mean antibiotic prescribing rates varied greatly by county (range, 39–2,482 prescriptions per 1,000 population). Physicians wrote the greatest number of antibiotic prescriptions (1,043,030 prescriptions, 54%) of which 56% were written by general pediatricians. Pediatricians graduating from medical school prior to 2000 were significantly more likely than those graduating after 2000 to be high antibiotic prescribers. Overall, 360 providers (1.7% of the 21,798 total providers in this dataset) were responsible for nearly 25% of both overall and broad-spectrum antibiotic prescriptions; 20% of these providers practiced in a single county.

Conclusions:

Fewer than 2% of providers account for 25% of pediatric antibiotic prescriptions. High antibiotic prescribing for children in Tennessee is associated with specific patient and provider characteristics that can be used to design stewardship interventions targeted to the highest prescribing providers in specific counties and specialties.

Type
Original Article
Information
Infection Control & Hospital Epidemiology , Volume 41 , Issue 3 , March 2020 , pp. 331 - 336
Copyright
© 2020 by The Society for Healthcare Epidemiology of America. All rights reserved.

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References

Sanchez, GV, Fleming-Dutra, KE, Roberts, RM, Hicks, LA.Core elements of outpatient antibiotic stewardship. MMWR Recomm Rep. 2016;65(6):1–12.CrossRefGoogle ScholarPubMed
Hicks, LA, Bartoces, MG, Roberts, RM, et al.US outpatient antibiotic prescribing variation according to geography, patient population, and provider specialty in 2011. Clin Infect Dis 2015;60:1308–1316.Google ScholarPubMed
Hersh, AL, Shapiro, DJ, Pavia, AT, Shah, SS.Antibiotic prescribing in ambulatory pediatrics in the United States. Pediatrics 2011;128:1053–1061.CrossRefGoogle ScholarPubMed
Fleming-Dutra, KE, Hersh, AL, Shapiro, DJ, et al.Prevalence of inappropriate antibiotic prescriptions among US ambulatory care visits, 2010–2011. JAMA 2016;315:1864–1873.CrossRefGoogle ScholarPubMed
National Action Plan for Combating Antibiotic-Resistant Bacteria, 2015. The White House website. https://obamawhitehouse.archives.gov/sites/default/files/docs/national_action_plan_for_combating_antibiotic-resistant_bacteria.pdf. Published 2015. Accessed March 23, 2019.Google Scholar
Hersh, AL, Shapiro, DJ, Pavia, AT, Fleming-Dutra, KE, Hicks, LA.Geographic variability in diagnosis and antibiotic prescribing for acute respiratory tract infections. Infect Dis Ther 2018;7:171–174.CrossRefGoogle ScholarPubMed
Outpatient antibiotic prescriptions—United States, 2016. Centers for Disease Control and Prevention website. https://www.cdc.gov/antibiotic-use/community/programs-measurement/state-local-activities/outpatient-antibiotic-prescriptions-US-2016.html. Published 2016. Accessed March 12, 2019.Google Scholar
Scarsbrook, AF, Ganeshan, A, Statham, J, et al.Anatomic and functional imaging of metastatic carcinoid tumors. Radiographics 2007;27:455–477.CrossRefGoogle ScholarPubMed
Ingram, DD, Franco, SJ.2013 NCHS urban-rural classification scheme for counties. National Center for Health Statistics. Vital Health Stat 2014;166:1–73.Google Scholar
Schmidt, ML, Spencer, MD, Davidson, LE. Patient, provider, and practice characteristics associated with inappropriate antimicrobial prescribing in ambulatory practices. Infect Control Hosp Epidemiol 2018;39:307–315.CrossRefGoogle ScholarPubMed
Fernandez-Lazaro, CI, Brown, KA, Langford, BJ, Daneman, N, Garber, G, Schwartz, KL.Late-career physicians prescribe longer courses of antibiotics. Clin Infect Dis 2019;69:1467–1475.CrossRefGoogle ScholarPubMed
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