Hostname: page-component-586b7cd67f-t8hqh Total loading time: 0 Render date: 2024-12-02T23:38:17.262Z Has data issue: false hasContentIssue false

Polymyxins A Word of Caution for Prudent Use of Valuable “Old Antibiotics”

Published online by Cambridge University Press:  21 June 2016

Matthew E. Falagas*
Affiliation:
Alfa Institute of Biomedical Sciences, Intensive Care Unit, “Henry Dunant” Hospital, Athens, Greece Department of Medicine, Intensive Care Unit, “Henry Dunant” Hospital, Athens, Greece Department of Medicine, Tufts University School of Medicine, Boston, Massachusetts
Sofia K. Kasiakou
Affiliation:
Alfa Institute of Biomedical Sciences, Intensive Care Unit, “Henry Dunant” Hospital, Athens, Greece
Argyris Michalopoulos
Affiliation:
Alfa Institute of Biomedical Sciences, Intensive Care Unit, “Henry Dunant” Hospital, Athens, Greece Intensive Care Unit, “Henry Dunant” Hospital, Athens, Greece
*
Alfa Institute of Biomedical Sciences (AIBS), 9 Neapoleos Street, Marousi 151 23, Greece, ([email protected])
Rights & Permissions [Opens in a new window]

Abstract

Image of the first page of this content. For PDF version, please use the ‘Save PDF’ preceeding this image.'
Type
Letters to the Editor
Copyright
Copyright © The Society for Healthcare Epidemiology of America 2006

References

1.Koch-Weser, J, Sidel, VW, Federman, EB, Kanarek, P, Finer, DC, Eaton, AE. Adverse effects of sodium colistimethate: manifestations and specific reaction rates during 317 courses of therapy. Ann Intern Med 1970; 72:857868.Google Scholar
2.Falagas, ME, Kasiakou, SK. Colistin: the revival of polymyxins for the management of multidrug-resistant gram-negative bacterial infections. Clin Infect Dis 2005; 40:13331341.Google Scholar
3.Michalopoulos, AS, Tsiodras, S, Rellos, K, Mentzelopoulos, S, Falagas, ME. Colistin treatment in patients with ICU-acquired infections caused by multiresistant gram-negative bacteria: the renaissance of an old antibiotic. Clin Microbiol Infect 2005; 11:115121.Google Scholar
4.Smith, CR, Lipsky, JJ, Laskin, OL, et al. Double-blind comparison of the nephrotoxicity and auditory toxicity of gentamicin and tobramycin. N Engl J Med 1980; 302:11061109.Google Scholar
5.Falagas, ME, Bliziotis, IA, Kasiakou, SK, Samonis, G, Athanassopoulou, P, Michalopoulos, A. Outcome of infections due to pandrug-resistant (PDR) gram-negative bacteria. BMC Infect Dis 2005; 5:24.Google Scholar