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The Past, Present, and Future of Healthcare-Associated Infection Prevention in Pediatrics: Catheter-Associated Bloodstream Infections

Published online by Cambridge University Press:  02 January 2015

Kristina A. Bryant ,
Danielle M. Zerr ,
W. Charles Huskins  and
Aaron M. Milstone
Kristina A. Bryant*
Affiliation:
Department of Pediatrics, University of Louisville, Louisville, Kentucky
Danielle M. Zerr
Affiliation:
Department of Pediatrics, University of Washington, Seattle
W. Charles Huskins
Affiliation:
College of Medicine, Mayo Clinic, Rochester, Minnesota
Aaron M. Milstone
Affiliation:
Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, Maryland
*
Pediatric Infectious Diseases, 571 South Floyd Street, Suite 321, Louisville, KY 40202 ([email protected])
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Abstract

Central line–associated bloodstream infections cause morbidity and mortality in children. We explore the evidence for prevention of central line–associated bloodstream infections in children, assess current practices, and propose research topics to improve prevention strategies.

Type
Supplement Article
Information
Infection Control & Hospital Epidemiology , Volume 31 , Issue S1: Papers from the Fifth Decennial International Conference on Healthcare-Associated Infections , November 2010 , pp. S27 - S31
Copyright
Copyright © The Society for Healthcare Epidemiology of America 2010

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References

1.Shulman, ST, Bratcher, DF, Brady, MT, Levine, GL, Jarvis, WR. Nosocomial infection rates in US childrens' hospitals' neonatal and pediatric intensive care units. Am J Infect Control 2001;29(3):152–157.Google Scholar
2.Marschall, J, Mermel, LA, Classen, D, et al.Strategies to prevent central line–associated bloodstream infection in acute care hospitals. Infect Control Hosp Epidemiol 2008;29(10 Suppl 1):S22–S30.CrossRefGoogle ScholarPubMed
3.O'Grady, NP, Alexander, M, Dellinger, EP, et al.Guidelines for the prevention of intravascular catheter-related infections. Am J Infect Control 2002;30(8):476–489.CrossRefGoogle ScholarPubMed
4.Milstone, AM, Bryant, KA, Huskins, WC, Zerr, DM. The past, present, and future of healthcare-associated infection prevention in pediatrics: multidrug-resistant organisms. Infect Control Hosp Epidemiol 2010;31(11 Suppl 1):S18–S21 (in this supplement).Google Scholar
5.Chaiyakunapruk, N, Veenstra, DL, Lipsky, BA, Saint, S. Chlorhexidine compared with povidone-iodine solution for vascular catheter-site care: a meta-analysis. Ann Intern Med 2002;136(11):792–801.CrossRefGoogle ScholarPubMed
6.Lund, CW, Kuller, J, Raines, DA, Ecklund, S, Achambault, ME, O'Flaherty, P. Neonatal Skin Care. 2nd ed. Washington, DC: Association of Women's Health, Obstetric and Neonatal Nurses; 2007.Google Scholar
7.Garland, JS, Alex, CP, Uhing, MR, Peterside, IE, Rentz, A, Harris, MC. Pilot trial to compare tolerance of chlorhexidine gluconate to povidone-iodine antisepsis for central venous catheter placement in neonates. J Perinatol 2009;29(12):808–813.Google Scholar
8.Andersen, C, Hart, J, Vemgal, P, Harrison, C. Prospective evaluation of a multifactorial prevention strategy on the impact of nosocomial infection in very low birth weight infants. J Hosp Infect 2005;61(2):162–167.CrossRefGoogle Scholar
9.Tamma, PD, Aucott, SW, Milstone, AM. Chlorhexidine use in the neonatal intensive care unit: results from a national survey. Infect Control Hosp Epidemiol 2010;31(8):846–849.CrossRefGoogle ScholarPubMed
10.Bleasdale, SC, Trick, WE, Gonzales, IM, Lyles, RD, Hayden, MK, Weinstein, RA. Effectiveness of chlorhexidine bathing to reduce catheter-associated bloodsteam infections in medical intensive care unit patients. Arch Intern Med 2007;167:2073–2079.CrossRefGoogle Scholar
11.Casey, AL, Worthington, T, Lambert, PA, Quinn, D, Faroqui, MH, Elliott, TS. A randomized, prospective clinical trial to assess the potential infection risk associated with the PosiFlow needleless connector. J Hosp Infect 2003;54(4):288–293.CrossRefGoogle ScholarPubMed
12.Soothill, JS, Bravery, K, Ho, A, Macqueen, S, Collins, J, Lock, P. A fall in bloodstream infections followed a change to 2% chlorhexidine in 70% isopropanol for catheter connection antisepsis: a pediatric single center before/after study on a hemopoietic stem cell transplant ward. Am J Infect Control 2009;37(8):626–630.Google Scholar
13.Menyhay, SZ, Maki, DG. Disinfection of needleless catheter connectors and access ports with alcohol may not prevent microbial entry: the promise of a novel antiseptic barrier cap. Infect Control Hosp Epidemiol 2006;27(1):23–27.CrossRefGoogle Scholar
14.Kaler, W, Chinn, R. Successful disinfection of needleless access ports: a matter of time and friction. J Assoc Vase Access 2007;12(3):140–142.Google Scholar
15.Chatzinikolaou, I, Zipf, TF, Hanna, H, et al.Minocycline-ethylenediami-netetraacetate lock solution for the prevention of implantable port infections in children with cancer. Clin Infect Dis 2003;36:116–119.CrossRefGoogle ScholarPubMed
16.Garland, JS, Alex, CP, Henrickson, KJ, McAuliffe, TL, Maki, DG. A vancomycin-heparin lock solution for prevention of nosocomial bloodstream infection in critically ill neonates with peripherally inserted central venous catheters: a prospective randomized trial. Pediatrics 2005;116(2):e198–e205.CrossRefGoogle ScholarPubMed
17.Fillipi, L, Pezzati, M, Amario, S, Poggi, P, Pecile, P. Fusidic acid and heparin lock solution for the prevention of catheter-related bloodstream infections in critically ill neonates: a retrospective study and a prospective randomized trial. Pediatr Crit Care Med 2007;8(6):556–562.CrossRefGoogle Scholar
18.Miller, MR, Griswold, M, Harris, JM, et al.Decreasing PICU catheter-associated bloodstream infections: NACHRI's quality transformation efforts. Pediatrics 2010;125(2):206–213.CrossRefGoogle ScholarPubMed
19.Jeffries, HE, Mason, W, Brewer, M, et al.Prevention of central venous catheter-associated bloodstream infections in pediatric intensive care units: a performance improvement collaborative. Infect Control Hosp Epidemiol 2009;30(7):645–651.CrossRefGoogle ScholarPubMed