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Outcomes of extended-spectrum beta-lactamases producing Enterobacteriaceae colonization among patients abdominal surgery patients

Published online by Cambridge University Press:  04 September 2019

Anucha Apisarnthanarak*
Affiliation:
Division of Infectious Diseases, Faculty of Medicine, Thammasat University, Prathum Thani, Thailand
Sumalee Kondo
Affiliation:
Division of Molecular Genetics and Molecular Biology, Faculty of Medicine, Thammasat University, Prathum Thani, Thailand
Chatchai Mingmalairak
Affiliation:
Department of Surgery, Faculty of Medicine, Thammasat University, Prathum Thani, Thailand
Prasit Mahawongkajit
Affiliation:
Department of Surgery, Faculty of Medicine, Thammasat University, Prathum Thani, Thailand
Jatupong Juntong
Affiliation:
Department of Surgery, Faculty of Medicine, Thammasat University, Prathum Thani, Thailand
Palin Limpavitayaporn
Affiliation:
Department of Surgery, Faculty of Medicine, Thammasat University, Prathum Thani, Thailand
Ekkapak Sriussadaporn
Affiliation:
Department of Surgery, Faculty of Medicine, Thammasat University, Prathum Thani, Thailand
Assanee Tongyoo
Affiliation:
Department of Surgery, Faculty of Medicine, Thammasat University, Prathum Thani, Thailand
Linda M. Mundy
Affiliation:
American Regent, Norristown, Pennsylvania
*
Author for correspondence: Anucha Apisarnthanarak, Email: [email protected]

Abstract

Preoperative enteric screening for extended-spectrum β-lactamase (ESBL)–producing Enterobacteriaceae was conducted in 360 patients prospectively observed for surgical site infection (SSI). ESBL colonization (adjusted odds ratio [aOR], 2.4) and dirty wound classification (aOR, 3.6) were associated with SSI; no association between carbapenem prophylaxis and reduction in SSI was detected.

Type
Concise Communication
Copyright
© 2019 by The Society for Healthcare Epidemiology of America. All rights reserved. 

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References

Kiratisin, P, Apisarnthanarak, A, Laesripa, C, Saifon, P. Molecular characterization and epidemiology of extended-spectrum-beta-lactamase-producing Escherichia coli and Klebsiella pneumoniae isolates causing health care-associated infection in Thailand, where the CTX-M family is endemic. Antimicrob Agents Chemother 2008;52:28182824.CrossRefGoogle ScholarPubMed
Apisarnthanarak, A, Kiratisin, P, Saifon, P, Kitphati, R, Dejsirilert, S, Mundy, LM. Clinical and molecular epidemiology of community-onset, extended-spectrum beta-lactamase-producing Escherichia coli infections in Thailand: a case-case-control study. Am J Infect Control 2007;35:606612.CrossRefGoogle ScholarPubMed
Teerawattanapong, N, Panich, P, Kulpokin, D, et al. A systematic review of the burden of multidrug-resistant healthcare-associated infections among intensive care unit patients in Southeast Asia: The rise of multidrug-resistant Acinetobacter baumannii . Infect Control Hosp Epidemiol 2018;39:525533.CrossRefGoogle ScholarPubMed
Turner, P, Pol, S, Soeng, S, et al. High prevalence of antimicrobial-resistant gram-negative colonization in hospitalized Cambodian infants. Pediatr Infect Dis J 2016;35:856861.CrossRefGoogle ScholarPubMed
Boo, NY, Ng, SF, Lim, VK. A case-control study of risk factors associated with rectal colonization of extended-spectrum beta-lactamase producing Klebsiella spp. in newborn infants. J Hosp Infect 2005;61:6874.CrossRefGoogle Scholar
Global guideline on preventions of surgical site infection. World Health Organization website. https://www.who.int/gpsc/ssi-prevention-guidelines/en/. Accessed May 26, 2016.Google Scholar
Anderson, DJ, Podgorny, K, Berrios-Torres, SI, et al. Strategies to prevent surgical site infections in acute care hospitals: 2014 update. Infect Control Hosp Epidemiol 2014;35:605627.CrossRefGoogle ScholarPubMed
Surgical site infection (SSI) event. Centers for Disease Control and Prevention website. https://www.cdc.gov/hai/pdfs/nhsn/9pscssi-sample.pdf. Published 2012. Accessed May 26, 2016.Google Scholar
Clinical and Laboratory Standards Institute. Performance Standards for Antimicrobial Susceptibility Testing: 26th Informational Supplement CLSI M100-S26. Wayne, PA: CLSI; 2016.Google Scholar
Pfeffer, I, Zemel, M, Kariv, Y, et al. Prevalence and risk factors for carriage of extended-spectrum β-lactamase-producing Enterobacteriaceae among patients prior to bowel surgery. Diagn Microbiol Infect Dis 2016; 85:377380.CrossRefGoogle ScholarPubMed
Dubinsky-Pertzov, B, Temkin, E, Harbarth, S, et al. Carriage of extended-spectrum beta-lactamase–producing Enterobacteriaceae and the risk of surgical site infection after colorectal surgery: a prospective cohort study. Clin Infect Dis 2019;68:16991704.CrossRefGoogle ScholarPubMed
Nutman, A, Temkin, E, Harbarth, S, et al. Personalized ertapenem prophylaxis for carrier of Extended-spectrum beta-lactamases producing Enterobacteriaceae undergoing colorectal surgery. Clin Infect Dis 2019. doi: 10.1093/cid/ciz524.CrossRefGoogle Scholar
Jazmati, N, Jazmati, T, Hamprecht, A. Importance of pre-enrichment for detection of third-generation cephalosporin-resistant Enterobacteriaceae (3GCREB) from rectal swabs. Eur J Clin Microbiol Infect Dis 2017;36:18471851.CrossRefGoogle ScholarPubMed