Hostname: page-component-669899f699-cf6xr Total loading time: 0 Render date: 2025-05-07T01:58:17.168Z Has data issue: false hasContentIssue false
  • English
  • Français

Outbreak of severe acute respiratory coronavirus virus 2 (SARS-CoV-2) in hospitalized hemodialysis patients: An epidemiologic and genomic investigation

Part of: SARS-CoV-2/COVID-19

Published online by Cambridge University Press:  06 December 2021

Charles E. Marvil ,
Ahmed Babiker Open the ORCID record for Ahmed Babiker [Opens in a new window] ,
Aaron Preston ,
Andrew S. Webster ,
Jeannette Guarner ,
Kari Love ,
Elham Ghonim ,
Paulina A. Rebolledo ,
Yun F. Wang  and
Robert A. Arthur
...Show all authors
Charles E. Marvil
Affiliation:
Emory University School of Medicine, Atlanta, Georgia Emory University, Atlanta, Georgia
Ahmed Babiker*
Affiliation:
Division of Infectious Diseases, Department of Medicine, Emory University School of Medicine, Atlanta, Georgia Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, Georgia
Aaron Preston
Affiliation:
Emory Health System, Atlanta, Georgia
Andrew S. Webster
Affiliation:
Division of Infectious Diseases, Department of Medicine, Emory University School of Medicine, Atlanta, Georgia Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, Georgia
Jeannette Guarner
Affiliation:
Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, Georgia
Kari Love
Affiliation:
Emory Health System, Atlanta, Georgia
Elham Ghonim
Affiliation:
Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, Georgia Grady Health System, Atlanta, Georgia
Paulina A. Rebolledo
Affiliation:
Division of Infectious Diseases, Department of Medicine, Emory University School of Medicine, Atlanta, Georgia Hubert Department of Global Health, Rollins School of Public Health, Atlanta, Georgia
Yun F. Wang
Affiliation:
Emory University School of Medicine, Atlanta, Georgia Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, Georgia
Robert A. Arthur
Affiliation:
Emory Integrated Computational Core, Emory Integrated Core Facilities, Emory University, Atlanta, Georgia
H. Richard Johnston
Affiliation:
Department of Human Genetics, Emory University, Atlanta, Georgia
Jesse J. Waggoner
Affiliation:
Division of Infectious Diseases, Department of Medicine, Emory University School of Medicine, Atlanta, Georgia
Anne Piantadosi
Affiliation:
Division of Infectious Diseases, Department of Medicine, Emory University School of Medicine, Atlanta, Georgia Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, Georgia
Jesse T. Jacob
Affiliation:
Division of Infectious Diseases, Department of Medicine, Emory University School of Medicine, Atlanta, Georgia
*
Author for correspondence: Ahmed Babiker, E-mail: [email protected]
Get access Rights & Permissions [Opens in a new window]

Abstract

We performed an epidemiological investigation and genome sequencing of severe acute respiratory coronavirus virus 2 (SARS-CoV-2) to define the source and scope of an outbreak in a cluster of hospitalized patients. Lack of appropriate respiratory hygiene led to SARS-CoV-2 transmission to patients and healthcare workers during a single hemodialysis session, highlighting the importance of infection prevention precautions.

Type
Concise Communication
Information
Infection Control & Hospital Epidemiology , Volume 44 , Issue 2 , February 2023 , pp. 332 - 334
Check for updates
Copyright
© The Author(s), 2021. Published by Cambridge University Press on behalf of The Society for Healthcare Epidemiology of America

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

Article purchase

Temporarily unavailable

Footnotes

a

Authors of equal contribution.

b

Authors of equal contribution.

References

Bigelow, BF, Tang, O, Toci, GR, et al. Transmission of SARS-CoV-2 involving residents receiving dialysis in a nursing home—Maryland, April 2020. Morb Mortal Wkly Rep 2020; 69: 1089–1094.CrossRefGoogle Scholar
Gupta, S, Hayek, SS, Wang, W, et al. Factors associated with death in critically ill patients with coronavirus disease 2019 in the US. JAMA Intern Med 2020; 180: 1436–1447.CrossRefGoogle ScholarPubMed
Waggoner, JJ, Stittleburg, V, Pond, R, et al. Triplex real-time RT-PCR for severe acute respiratory syndrome coronavirus 2. Emerg Infect Dis 2020; 26: 1633–1635.CrossRefGoogle ScholarPubMed
Babiker, A, Bradley, HL, Stittleburg, VD, et al. Metagenomic sequencing to detect respiratory viruses in persons under investigation for COVID-19. J Clin Microbiol 2020;59:e02142–20.CrossRefGoogle ScholarPubMed
Jacob, JT, Baker, JM, Fridkin, SK, et al. Risk factors associated with SARS-CoV-2 seropositivity among US healthcare personnel. JAMA Netw Open 2021;4:e211283.CrossRefGoogle Scholar
Schwierzeck, V, König, JC, Kühn, J, et al. First reported nosocomial outbreak of severe acute respiratory syndrome coronavirus 2 in a pediatric dialysis unit. Clin Infect Dis 2021; 72: 265–270.CrossRefGoogle Scholar
Yau, K, Muller, MP, Lin, M, et al. COVID-19 outbreak in an urban hemodialysis unit. Am J Kidney Dis 2020;76:690–5.e1.CrossRefGoogle Scholar
Iio, R, Kaneko, T, Mizuno, H, Isaka, Y. Clinical characteristics of COVID-19 infection in a dialysis center during a nosocomial outbreak. Clin Exp Nephrol 2021; 25: 652–659.CrossRefGoogle Scholar
Babiker, A. mSphere of influence: whole-genome sequencing, a vital tool for the interruption of nosocomial transmission. mSphere 2021;6:e00230–21.CrossRefGoogle ScholarPubMed
Supplementary material: File

Marvil et al. supplementary material

Marvil et al. supplementary material

Download Marvil et al. supplementary material(File)
File 1.3 MB