Hostname: page-component-586b7cd67f-gb8f7 Total loading time: 0 Render date: 2024-11-28T08:43:43.919Z Has data issue: false hasContentIssue false

Outbreak of Burkholderia cepacia Bloodstream Infection at an Outpatient Hematology and Oncology Practice

Published online by Cambridge University Press:  02 January 2015

Karon Abe*
Affiliation:
Division of Public Health, Georgia Department of Human Resources, Centers for Disease Control and Prevention, Atlanta, Georgia Epidemic Intelligence Service, Office of Workforce and Career Development, Centers for Disease Control and Prevention, Atlanta, Georgia
Melissa Tobin D'Angelo
Affiliation:
Division of Public Health, Georgia Department of Human Resources, Centers for Disease Control and Prevention, Atlanta, Georgia
Rebecca Sunenshine
Affiliation:
Division of Healthcare Quality Promotion, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia
Judith Noble-Wang
Affiliation:
Division of Healthcare Quality Promotion, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia
James Cope
Affiliation:
Division of Public Health, Georgia Department of Human Resources, Centers for Disease Control and Prevention, Atlanta, Georgia
Bette Jensen
Affiliation:
Division of Healthcare Quality Promotion, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia
Arjun Srinivasan
Affiliation:
Division of Healthcare Quality Promotion, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia
*
CDC/DRH/MIHB, 4770 Buford Hwy., MS K-23, Atlanta, GA30341 ([email protected])

Abstract

We investigated an outbreak of infection in 10 patients with blood cultures positive for B. cepacia. All patients had indwelling intravenous catheters. Though we did not identify the source of the organism, our findings support the hypothesis that cross-contamination of multidose medications through the use of the same needle and syringe was a contributing factor.

Type
Concise Communications
Copyright
Copyright © The Society for Healthcare Epidemiology of America 2007

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

1.Mangram, A, Jarvis, WR. Nosocomial Burkholderia cepacia outbreaks and pseudo-outbreaks. Infect Control Hosp Epidemiol 1996;17:718720.Google Scholar
2.Martone, WJ, Tablan, OC, Jarvis, WR. The epidemiology of nosocomial epidemic Pseudomonas cepacia infections. Eur J Epidemiol 1987;3:222232.CrossRefGoogle ScholarPubMed
3.Woods, CW, Bressler, AM, LiPuma, JJ, et al. Virulence associated with outbreak-related strains of Burkholderia cepacia complex among a cohort of patients with bacteremia. Clin Infect Dis 2004;38:12431250.Google Scholar
4.Maslow, J, Slutsky, A, Arbeit, R. Application of pulsed-field gel electrophoresis to molecular epidemiology. In: Persing, D, Smith, T, Tenover, F, White, T, eds. Diagnostic Molecular Microbiology: Principles and Applications. Washington DC: ASM Press, 1993:563572.Google Scholar
5.Martino, R, Gomez, L, Pericas, R, et al. Bacteraemia caused by non-glucose-fermenting gram-negative bacilli and Aeromonas species in patients with haematological malignancies and solid tumours. Eur J Clin Microbiol Infect Dis 2000;19:320323.CrossRefGoogle ScholarPubMed
6.Zinner, SH. Changing epidemiology of infections in patients with neutropenia and cancer: emphasis on gram-positive and resistant bacteria. Clin Infect Dis 1999;29:490494.CrossRefGoogle ScholarPubMed
7.Donlan, RM. Biofilms: microbial life on surfaces. Emerg Infect Dis 2002;8:881890.Google Scholar
8.Tanaka, T, Takahashi, H, Kobayashi, JM, Ohyama, T, Okabe, N. A nosocomial outbreak of febrile bloodstream infection caused by heparinized-saline contaminated with Serratia marcescens, Tokyo, 2002. Jpn J Infect Dis 2004;57:189192.Google ScholarPubMed
9.Transmission of hepatitis B and C viruses in outpatient settings—New York, Oklahoma, and Nebraska, 2000-2002.MMWK Morb Mortal Wkly Rep 2003;52:901906.Google Scholar