Hostname: page-component-78c5997874-ndw9j Total loading time: 0 Render date: 2024-11-03T02:41:05.272Z Has data issue: false hasContentIssue false

Number of Comorbidities as a Predictor of Nosocomial Infection Acquisition

Published online by Cambridge University Press:  21 June 2016

Peter A. Gross*
Affiliation:
Department of Internal Medicine, Hackensack Medical Center, Hackensack, New Jersey and New Jersey Medical School, Newark, New Jersey and School of Public Health (Biostatistics), College of Physicians and Surgeons, Columbia University, New York, New York
Peter J. DeMauro
Affiliation:
Department of Internal Medicine, Hackensack Medical Center, Hackensack, New Jersey and New Jersey Medical School, Newark, New Jersey and School of Public Health (Biostatistics), College of Physicians and Surgeons, Columbia University, New York, New York
Carole Van Antwerpen
Affiliation:
Department of Internal Medicine, Hackensack Medical Center, Hackensack, New Jersey and New Jersey Medical School, Newark, New Jersey and School of Public Health (Biostatistics), College of Physicians and Surgeons, Columbia University, New York, New York
Sylvan Wallenstein
Affiliation:
Department of Internal Medicine, Hackensack Medical Center, Hackensack, New Jersey and New Jersey Medical School, Newark, New Jersey and School of Public Health (Biostatistics), College of Physicians and Surgeons, Columbia University, New York, New York
Stanley Chiang
Affiliation:
Department of Internal Medicine, Hackensack Medical Center, Hackensack, New Jersey and New Jersey Medical School, Newark, New Jersey and School of Public Health (Biostatistics), College of Physicians and Surgeons, Columbia University, New York, New York
*
Department of Internal Medicine, Hackensack Medical Center, 30 Prospect Avenue, Hackensack, NJ 07601

Abstract

Infection control programs are primarily oriented toward chronicling the incidence of nosocomial infections (NI). Intervention programs oriented toward preventing infection would be facilitated by identifying patients at greatest risk of NI acquisition. We studied the number of comorbidities as a risk predictor for NIs in patients admitted to the medical intensive care unit (ICU) for three or more days. In 148 patients, we found by regression analysis that the number of comorbidities varied directly with the development of nosocomial infections, as well as with the appearance of new complications and length of ICU stay. Diagnosis-related groups did not adequately account for the variance in comorbidities observed.

Type
Original Articles
Copyright
Copyright © The Society for Healthcare Epidemiology of America 1988

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

1. Thompson, RL: Surveillance and reporting of nosocomial infections, in Wenzel, RP (ed): Prevention and Control of Nosocomial Infections. Baltimore, Williams & Wilkins, 1987, pp 7082.Google Scholar
2. Wong, ES. Hooten, IM: Guidelines for prevention of catheter-associated urinary tract infections. Infect Control 1981: 2:120130.CrossRefGoogle Scholar
3. Krebs, M, Halvorsen, PB. Fishman, IJ. et al: Prevention of urinary tract infection during intermittent catheterization. J Urol 1984: 131:8285.CrossRefGoogle ScholarPubMed
4. Garibaldi, RA, Burke, JE, Dickman, ML,, et al: Factors predisposing to bacteriuria during indwelling urethral catheterization. N Engl J Med 1974; 291:215219.CrossRefGoogle ScholarPubMed
5. Simmons, BP: CDC guidelines for the prevention and control of nosocomial infections: Guideline for prevention of intravascular infections. Am J Infect Control 1983; 11:183199.CrossRefGoogle ScholarPubMed
6. Krieger, JM, Kaiser, DF, Wenzel, RP: Urinary tract etiology of bloodstream infections in hospitalized patients. J Infect Dis 1983; 148:5762.CrossRefGoogle ScholarPubMed
7. Maki, DG: Nosocomial bacteremia: An epidemiologic overview. Am J Med 1981; 70:719732.CrossRefGoogle Scholar
8. Wenzel, RP. Thompson, RL, Landry, SM, et al: Hospital-acquired infections in intensive care unit patients: An overview with emphasis on epidemics. Infect Control 1983; 4:371375.CrossRefGoogle ScholarPubMed
9. Britt, MR. Schleupner, CJ, Matsumiva, S: Severity of underlying disease as a predictor of nosocomial infections: Utility in the control of nosocomial infection. JAMA 1978; 2398:10471051.CrossRefGoogle Scholar
10. Shakno, RJ (ed): Physicians Guide to DRGs. Chicago, Pluribus Press. Inc. 1984. p 232.Google Scholar
11. US Department of Health and Human Services. Centers for Disease Control: NNIS Manual. National Nosocomial Infections Surveillance Systems, 1980.Google Scholar
12. Fetter, RB, Shin, Y. Freeman, JL, et al: Case mix definition bv diagnosis-related groups. Med Care 1980; 18(suppl):153.Google Scholar
13. Health Systems Management Group, Yale School of Organization and Management. The new ICD-9-CM diagnosis-related group classification scheme, Final Report. May 1982.Google Scholar
14. McCullagh, P. Neider, JA: Generalized Linear Models. Landau. Chapman and Hall, 1983, p 300.CrossRefGoogle Scholar
15. National Academy of Sciences—National Research Council: Postoperative wound infections: The influence of ultraviolet irradiation of the operating room and of the various other factors. Ann Surg 1904: 160(suppl 2): 132.Google Scholar
16. Altemeier, WA, Burke, JF, Pruitt, BA. et al (eds): Manual on Control of Infection in Surgical Patients, ed 2. Philadelphia, JB Lippincott. 1984. p 389.Google Scholar
17. Cruse, P: Surgical infectious: Incisional wounds, in Bennett, JV, Brachman, PS (eds): Hospital Infections, ed 2. Boston, Little, Brown and Co, 1985, pp 423430.Google Scholar
18. Hooton, TM, Haley, RW. Culver, DH, et al: The joint association of multiple risk factors with the occurrence of nosocomial infection. Am J Med 1981; 70:960970.CrossRefGoogle Scholar
19. McCabe, WR, Jackson, GG: Gram-negative bacteremia: I. Etiology and ecology. Arch Intern Med 1962; 110:847855.CrossRefGoogle Scholar