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Nosocomial Penicillin-Resistant Pneumococcal Infections at a Midwestern University Hospital

Published online by Cambridge University Press:  02 January 2015

J. Russell Little ,
James Miller  and
Michael G. Kahn
J. Russell Little*
Affiliation:
Washington University School of Medicine, St Louis, Missouri
James Miller
Affiliation:
Washington University School of Medicine, St Louis, Missouri
Michael G. Kahn
Affiliation:
Barnes-Jewish Hospital, St Louis, Missouri
*
Washington University School of Medicine, Box 8051, 660 S Euclid Ave, St Louis, MO 63110-1093
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Abstract

We analyzed 333 isolates of Streptococcus pneumoniae from adult inpatients over a continuous 30-month period. Twenty-five percent of isolates were resistant to penicillin, and 18% of tested strains were not susceptible to ceftriaxone. For 29 (15%) of 199 evaluable patients, S pneumoniae was isolated from a culture first obtained >48 hours after admission, and chart review satisfied our case definition for nosocomial infection. S pneumoniae isolates were penicillin-resistant in 14 of 29 nosocomial and 34 of 170 community-acquired cases (odds ratio, 3.73; 95% confidence interval, 1.53-9.15; P =.01)

Type
Concise Communications
Information
Infection Control & Hospital Epidemiology , Volume 19 , Issue 10 , October 1998 , pp. 782 - 784
Copyright
Copyright © The Society for Healthcare Epidemiology of America 1998

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