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Nosocomial Group B Streptococcal Infections

Published online by Cambridge University Press:  21 June 2016

Natalie C. Klein
Affiliation:
Infectious Disease Division and the Department of Pathology, Winthrop-University Hospital, Mineola, New York
Paul E. Schoch
Affiliation:
Infectious Disease Division and the Department of Pathology, Winthrop-University Hospital, Mineola, New York
Burke A. Cunha*
Affiliation:
Infectious Disease Division and the Department of Pathology, Winthrop-University Hospital, Mineola, New York
*
Chief, Infectious Disease Division, Winthrop-University Hospital, Mineola, NY 11501

Extract

Group B streptococci are the most frequent cause of life-threatening infections in newborn infants in the United States. The reservoir of this organism is thought to be the mother's vaginal or rectal microflora or both. Prevalence surveys have documented arriage rates ranging from 8% to 31%. Increased rates of vertical transmission are seen in infants born to women with dense vaginal colonization at delivery. In most cases, early onset group B streptococcal disease in neonates is diagnosed during the first day of life.' While the carrier rate may approach 30% in pregnant women, the incidence of serious disease in neonates is 0.2% to 0.4% with a mortality rate approaching 50% in some studies. Risk factors prominently associated with early onset group B streptococcal disease have been identified as premature labor, prolonged rupture of amniotic membranes and intrapartum fever.

Type
Special Sections
Copyright
Copyright © The Society for Healthcare Epidemiology of America 1989

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