Hostname: page-component-586b7cd67f-rdxmf Total loading time: 0 Render date: 2024-11-30T21:34:45.397Z Has data issue: false hasContentIssue false
  • English
  • Français

Lyme Borreliosis

Published online by Cambridge University Press:  21 March 2023

Douglas A. Holt ,
Namrata J. Pattani ,
John T. Sinnott  and
Elizabeth Bradley
Douglas A. Holt
Affiliation:
Division of Infectious and Tropical Diseases, Department of Internal Medicine, The University of South Florida College of Medicine, Tampa, Florida
Namrata J. Pattani
Affiliation:
Division of Infectious and Tropical Diseases, Department of Internal Medicine, The University of South Florida College of Medicine, Tampa, Florida
John T. Sinnott*
Affiliation:
Division of Infectious and Tropical Diseases, Department of Internal Medicine, The University of South Florida College of Medicine, Tampa, Florida
Elizabeth Bradley
Affiliation:
Division of Infectious and Tropical Diseases, Department of Internal Medicine, The University of South Florida College of Medicine, Tampa, Florida
*
The Tampa General Hospital, P.O. Box 1289, Tampa, FL 33601
Get access Rights & Permissions [Opens in a new window]

Extract

Lyme borreliosis (also known as Lyme disease) has become the most commonly reported tick-transmitted disease in the United States.’ The diverse clinical manifestations of the disease make diagnosis difficult, but Lyme borreliosis is quite responsive to treatment if recognized in the early stages.

In the early part of the century, Afzelius in Sweden and Lipschutz in Austria described a distinctive skin lesion, erythema chronicum migrans (ECM), which developed at the site of a previous tick bite. Later, Garin and Bujadoux in France, Hellerström in Sweden, and Bannwarth in Germany described the association of ECM with neurological diseases, including neuropathies, radiculopathies, and cranial nerve palsies. Lyme disease was first recognized as a separate syndrome in the United States by Dr. Allen Steere and his colleagues in 1976, after a homemaker, MS Polly Murray, brought an outbreak of arthritis to their attention. Epidemiological studies of this unusual geographical clustering of children in Lyme, Connecticut, who were thought to have juvenile rheumatoid arthritis, suggested another process. The illness was eventually found to be caused by a vectorborne spirochete, Borrelia burgdorferi, which is capable of infecting the cardiovascular, dermatologic, neurologic, and musculoskeletal systems.

Type
Topics in Clinical Microbiology
Information
Infection Control & Hospital Epidemiology , Volume 12 , Issue 8 , August 1991 , pp. 493 - 496
Copyright
Copyright © The Society for Healthcare Epidemiology of America 1991

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

1. Steere, A, Malawista, SE, Hardin, JA, Ruddy, S, Askenase, PW, Andiman, WA. Erythema chronicum migrans and Lyme arthritis. Ann Intern Med. 1977;86:685–697.CrossRefGoogle ScholarPubMed
2. Centers for Disease Control. Lyme disease-Connecticut. MMWR. 1988;37:1–3.Google Scholar
3. Afzelius, A. Erythema chronicum migrans. Acta Derm Venereol (Stockh). 1921;2:120–125.Google Scholar
4. Lipschutz, B. Wsiterer Beitrag zur kenntnis des erythema chronicum migrans. Archives of Dermatology and Syphilology. 1923;143:365–374.CrossRefGoogle Scholar
5. Garin, CH, Bujadoux, C. Paralysie par les tiques. Journal de Medicine de Lyon. 1922;77:765–767.Google Scholar
6. Hellerström, S. Erythema chronicum migrans Afzelii. Acta Derm Venereol. 1930;11:315–321.Google Scholar
7. Bannwarth, A. Chronische lymphocytare meningitis, entzundlithe poyneuritis und rheumatismus. Archiv fur Psychiatrie und Nervenkrankheiten. 1941;113:284–376.CrossRefGoogle Scholar
8. Centers for Disease Control. Lyme Disease-United States, 1987 and 1988. MMWR. 1989;38:668–672.Google Scholar
9. Ciesielski, CA, Markowitz, LE, Horsley, R, et al. Lyme Disease surveillance in the United States, 1983-1986. Rev Infect Dis. 1989;2:S1435–S1441.CrossRefGoogle Scholar
10. Ciesielski, CA, Markowitz, LE, Horsley, R, et al. The geographic distribution of Lyme disease in the United States. Ann NY Acad Sci. 1988;539:283–288.CrossRefGoogle ScholarPubMed
11. Schmid, GE The global distribution of Lyme disease. Rev Infect Dis. 1985;7:41–50.CrossRefGoogle ScholarPubMed
12. McKenna, DE Lyme disease: a review for the primary health care providers. Nurse Practitioner. 1989;14:18–29.CrossRefGoogle ScholarPubMed
13. Steere, AC, Bartenhagen, NH, Craft, JE, et al. The early clinical manifestations of Lvme disease. Ann Intern Med. 1983;99:76.CrossRefGoogle Scholar
14. Goldstein, J. Lyme disease. Internal Medicine. 1987;8:82–90.Google Scholar
15. Sorensen, IR. Lyme disease: neurological manifestations. Comprehensive Therapy. 1989;15:16–22.Google Scholar
16. Johnson, RC, Schmid, GP, Hyde, FW, et al. Borrelia burgdorferi sp. Nov. etiologic agent of Lyme disease. Int J Sys Bacteriol. 1984;34:496–497.CrossRefGoogle Scholar
17. Barbour, AG, Burgdorfer, W, Hayes, SF, et al. Isolation of cultivable spirochete from Ixodes ricinus of Switzerland. Curr Microbiol. 1983;8:123–126.CrossRefGoogle Scholar
18. Barbour, AG, Burgdorfer, W, Grunwaldt, E, et al. Antibodies of patients with Lyme disease to components of Zxodes dammini spirochete. J Clin Invest. 1983;72:504–515.CrossRefGoogle ScholarPubMed
19. Coleman, JL, Benach, JL. Isolation of antigenic components from the Lyme disease spirochete: their role in early diagnosis. J Infect Dis. 1987;155:756–765.CrossRefGoogle ScholarPubMed
20. Kelly, R. Cultivation of Borrelia hermsii . Science. 1971;173:443.CrossRefGoogle Scholar
21. Benach, JL, Szczepanski, A, Monco, JCG. Biological features of Borrelia burgdorferi . Laboratory Medicine. 1990;21:293–298.CrossRefGoogle Scholar
22. Steere, AC, Grodzicki, RL, Kornblatt, AN, et al. The spirochetal etiology of Lyme disease. N Engl J Med. 1983;308:733–740.CrossRefGoogle ScholarPubMed
23. Benach, JL, Bosler, EM, Hanrahan, JP, et al. Spirochetes isolated from the blood of two patients with Lyme disease. N Engl J Med. 1983;308:740–742.CrossRefGoogle ScholarPubMed
24. Kornblatt, AN, Urband, PH, Steere, AC. Arthritis caused by Borrelia burgdorferi in dogs. J Am Vet Med Assoc. 1985;186:960–964.Google ScholarPubMed
25. Marcus, LC, Patterson, MM, Gilfillain, RE, Urband, PH. Antibodies to Borrelia burgdorferi in New England horses: serologic survey. Am J Vet Res. 1985:46:2570–2571.Google ScholarPubMed
26. Burgess, EC. Borrelia burgdorferi infection in Wisconsin horses and cows . Ann NY Acad Sci. 1988;539:235–243.CrossRefGoogle ScholarPubMed
27. Steere, AC, Broderick, TF, Malawista, SE. Erythema chronicum migrans and Lyme arthritis: epidemiological evidence for a tick vector. Am J Epidemiol. 1978;108:312–321.CrossRefGoogle ScholarPubMed
28. Reik, L Jr, Burgdorfer, W, Donaldson, JO. Neurologic abnormalities in Lyme disease without erythema chronicum migrans. Am J Med. 1986;81:73–78.CrossRefGoogle ScholarPubMed
29. Asbrink, E, Hovmark, A. Early and late cutaneous manifestations of Ixodes-borne borreliosis (erythema migrans borreliosis, Lyme borreliosis). Ann NY Acad Sci. 1988:539:4–15.CrossRefGoogle Scholar
30. Dattwyler, RJ. Lyme borreliosis: an overview of the clinical manifestations. Laboratory Medicine. 1990;21:290–292.CrossRefGoogle Scholar
31. Watch out for the tick attack. Publications of Consumers Union. 1988:382–385.Google Scholar
32. Steere, A, Green, J, Schoen, RT, et al. Successful parenteral penicillin therapy of established Lyme arthritis. N Engl J Med. 1985;312:869-73–39.CrossRefGoogle ScholarPubMed
33. Golighty, M, Thomas, JA, Viciana, A. The laboratory diagnosis of Lyme borreliosis. Laboratory Medicine. 1990;21:299–304.CrossRefGoogle Scholar
34. Craft, JE, Grodzicki, RL, Steere, AC. The antibody response in Lyme disease: evaluation of diagnostic tests. J Infect Dis. 1984;149:789–795.CrossRefGoogle ScholarPubMed
35. Russell, H, Sampson, JS, Scmid, GP, Wilkinson, HW, Plikaytis, B. Enzyme linked immunosorbent assay and indirect immunofluorescence assay for Lyme disease. J Infect Dis. 1984;149:465–470.CrossRefGoogle ScholarPubMed
36. Magnarelli, LA, Meegan, JM, Anderson, JF, Chappell, WA. Comparison of an indirect fluorescent-antibody test with an enzyme linked immunosorbent assay for serological studies of Lyme disease. J Clin Microbial. 1984:20:181–184.CrossRefGoogle ScholarPubMed
37. Shrestha, A, Grodzick, RL, Steere, AC. Diagnosing early Lyme disease. Am J Med. 1985;78:235–239.CrossRefGoogle ScholarPubMed
38. Relman, D, Swartz, MN. Leptospirosis, relapsing fever, rat-bite fever, and Lyme disease. Scientific American Medicine. 1988;2:4–10.Google Scholar
39. Borenstein, D. Lyme disease. Drug Therapy. 1990;20:86–90.Google Scholar
40. Wormser, GE Treatment of Borrelia burgdorferi infection. Laboratory Medicine. 1990;21:316–321.CrossRefGoogle Scholar
41. Markowitz, L, Steere, AC, Benach, JL, et al. Lyme disease during pregnancy. JAMA. 1986;255:3394–3396.CrossRefGoogle ScholarPubMed
42. Schlesinger, PA, Duray, PH, Burke, BA, et al. Maternal-fetal transmission of the Lyme disease spirochete, Borrelia burgdorferi . Ann Intern Med. 1985;103:67–68.CrossRefGoogle ScholarPubMed
43. Steere, AC. Lyme disease. N Engl J Med. 1989;321:586–596.CrossRefGoogle ScholarPubMed